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Proline (CID 614) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(160)
 
 
Inconclusive(5)
 
 
Unspecified(7)
 
 
Top Targets:
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
NR LBD TR(5)
 
 
NR LBD GR(4)
 
 
 
PLDc mTdp1 2(3)
 
 
BioAssay Types:
Confirmatory(132)
 
 
 
Summary(15)
 
 
Literature(11)
 
 
 
 
Screening(7)
 
 
BioActivity Types:
Potency(87)
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 169    Data Row: 175   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103271944]
IC50 17.2Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 [AID143614, Type: Literature]
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2
[SID103271944]
Induction of systemic acquired resistance in Brassica oleracea (white cabbage) plants assessed as increase in glucanase activity at 100 mM sprayed on leaves of 3 weeks old seedlings by colorimetric assay [AID1089396, Type: Literature]
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3
[SID103271944]
Induction of systemic acquired resistance in Brassica oleracea (white cabbage) plants assessed as increase in chitinase activity at 100 mM sprayed on leaves of 3 weeks old seedlings by colorimetric assay [AID1089397, Type: Literature]
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4
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 25 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089402, Type: Literature]
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5
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 50 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089403, Type: Literature]
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6
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 100 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089404, Type: Literature]
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7
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 2.5 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089407, Type: Literature]
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8
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 10 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089408, Type: Literature]
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9
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 5 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089409, Type: Literature]
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10
[SID103271944]
Percent inhibition against dihydrodipicolinic acid synthase at 5 mM [AID56934, Type: other]
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11
[SID29217981]
Potency 42.2841qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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12
[SID144203593]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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13
[SID144203593]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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14
[SID144203593]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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15
[SID144203593]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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16
[SID144203593]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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17
[SID144203593]
Ratio Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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18
[SID144203593]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
19
[SID144203593]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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20
[SID144203593]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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