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BioActivity Data for Compound Proline (CID 614)

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BioActivity Outcomes:
Active(3)
 
 
Inactive(160)
 
 
Inconclusive(5)
 
 
Unspecified(7)
 
 
Top Targets:
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
NR LBD TR(5)
 
 
NR LBD GR(4)
 
 
 
PLDc mTdp1 2(3)
 
 
BioAssay Types:
Confirmatory(132)
 
 
 
Summary(15)
 
 
Literature(11)
 
 
 
 
Screening(7)
 
 
BioActivity Types:
Potency(87)
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 169    Data Row: 175   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103271944]
IC50 17.2Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 [AID143614, Type: Literature]
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2
[SID103271944]
Induction of systemic acquired resistance in Brassica oleracea (white cabbage) plants assessed as increase in glucanase activity at 100 mM sprayed on leaves of 3 weeks old seedlings by colorimetric assay [AID1089396, Type: Literature]
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3
[SID103271944]
Induction of systemic acquired resistance in Brassica oleracea (white cabbage) plants assessed as increase in chitinase activity at 100 mM sprayed on leaves of 3 weeks old seedlings by colorimetric assay [AID1089397, Type: Literature]
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4
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 25 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089402, Type: Literature]
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5
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 50 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089403, Type: Literature]
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6
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 100 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089404, Type: Literature]
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7
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 2.5 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089407, Type: Literature]
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8
[SID103271944]
Percent inhibition against dihydrodipicolinic acid synthase at 5 mM [AID56934, Type: other]
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9
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 10 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089408, Type: Literature]
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10
[SID103271944]
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 5 mM sprayed on leaves of one week old seedlings relative to untreated control [AID1089409, Type: Literature]
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11
[SID29217981]
Potency 42.2841qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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12
[SID144203593]
Potency-Replicate_1 qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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13
[SID144203593]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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14
[SID144203593]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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15
[SID144203593]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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16
[SID144203593]
Ratio Potency (uM) qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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17
[SID29217981]
Potency qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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18
[SID144203593]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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19
[SID144203593]
ATAD5 Potency (uM) qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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20
[SID29217981]
Potency qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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