| 1 | [SID103222496] | Active | Km | 5 | Substrate activity with rat Methionine adenosyltransferase II [AID107897, Type: Literature] | |   View X | Row No. | 1 | | Structure | 
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Active | | Km | 5 [uM] | | BioAssay | Substrate activity with rat Methionine adenosyltransferase II | | AID | 107897 | | BioAssay type | Literature | | Target | | | PubMed | 3755757 | | Data Table | |
|
| 2 | [SID103222496] | Active | Km | 5 | Michaelis constant (KM) was evaluated [AID17451, Type: Literature] | | View X | Row No. | 2 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Active | | Km | 5 [uM] | | BioAssay | Michaelis constant (KM) was evaluated | | AID | 17451 | | BioAssay type | Literature | | Target | | | PubMed | 3486976 | | Data Table | |
|
| 3 | [SID103222496] | Active | Km | 15.6 | Substrate activity with normal tissue (M-T) form of rat methionine Adenosyltransferase [AID34131, Type: Literature] | | View X | Row No. | 3 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Active | | Km | 15.6 [uM] | | BioAssay | Substrate activity with normal tissue (M-T) form of rat methionine Adenosyltransferase | | AID | 34131 | | BioAssay type | Literature | | Target | | | PubMed | 3755757 | | Data Table | |
|
| 4 | [SID46393022] | Active | | | Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature] | Chain A, Streptomyces Griseus Aminopeptidase Complexed With Methionine [gi:7766866] | View X | Row No. | 4 | | Structure |
| | Substance | | | SID | 46393022 | | CID | 6137 | | Outcome | Active | | BioAssay | Experimentally measured binding affinity data derived from PDB | | AID | 1811 | | BioAssay type | Literature | | Target | Chain A, Streptomyces Griseus Aminopeptidase Complexed With Methionine [gi:7766866] | | PubMed | 10771423 | | Data Table | |
|
| 5 | [SID46392872] | Active | | | Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature] | Chain A, Methionyl-Trna Synthetase From Escherichia Coli Complexed With Methionine And Adenosine [gi:46015206] | View X | Row No. | 5 | | Structure |
| | Substance | | | SID | 46392872 | | CID | 6137 | | Outcome | Active | | BioAssay | Experimentally measured binding affinity data derived from PDB | | AID | 1811 | | BioAssay type | Literature | | Target | Chain A, Methionyl-Trna Synthetase From Escherichia Coli Complexed With Methionine And Adenosine [gi:46015206] | | PubMed | 12946347 | | Data Table | |
|
| 6 | [SID46393499] | Active | | | Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature] | Chain A, The Product Bound Form Of The Mn(Ii)loaded Methionine Aminopeptidase From Hyperthermophile [gi:61680215] | View X | Row No. | 6 | | Structure |
| | Substance | | | SID | 46393499 | | CID | 6137 | | Outcome | Active | | BioAssay | Experimentally measured binding affinity data derived from PDB | | AID | 1811 | | BioAssay type | Literature | | Target | Chain A, The Product Bound Form Of The Mn(Ii)loaded Methionine Aminopeptidase From Hyperthermophile [gi:61680215] | | PubMed | 15628852 | | Data Table | |
|
| 7 | [SID103222496] | Unspecified | Ki | 61 | Inhibition of cobalt substituted Bacillus subtilis LuxS [AID264583, Type: Literature] | S-ribosylhomocysteine lyase [gi:7387851] | View X | Row No. | 7 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | Ki | 61 [uM] | | BioAssay | Inhibition of cobalt substituted Bacillus subtilis LuxS | | AID | 264583 | | BioAssay type | Literature | | Target | S-ribosylhomocysteine lyase [gi:7387851] | | PubMed | 16686542 | | Data Table | |
|
| 8 | [SID103222496] | Unspecified | Km | 70 | Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liver [AID200229, Type: Literature] | | View X | Row No. | 8 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | Km | 70 [uM] | | BioAssay | Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liver | | AID | 200229 | | BioAssay type | Literature | | Target | | | PubMed | 9873403 | | Data Table | |
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| 9 | [SID103222496] | Unspecified | EC50 | 800 | Concentration required for obtaining 50% of the fluorescence intensity of copper-free calcein 1, in bovine serum albumin [AID51033, Type: Literature] | | View X | Row No. | 9 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | EC50 | 800 [uM] | | BioAssay | Concentration required for obtaining 50% of the fluorescence intensity of copper-free calcein 1, in bovine serum albumin | | AID | 51033 | | BioAssay type | Literature | | Target | | | PubMed | 12729634 | | Data Table | |
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| 10 | [SID103222496] | Unspecified | Km | 2600 | Effect on Salinispora tropica CNB-440 wild type recombinant SalL expressed in Escherichia coli BL21(DE3)-mediated S-Adenosyl methionine formation after 30 mins by HPLC analysis [AID498933, Type: Literature] | | View X | Row No. | 10 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | Km | 2600 [uM] | | BioAssay | Effect on Salinispora tropica CNB-440 wild type recombinant SalL expressed in Escherichia coli BL21(DE3)-mediated S-Adenosyl methionine formation after 30 mins by HPLC analysis | | AID | 498933 | | BioAssay type | Literature | | Target | | | PubMed | 18059261 | | Data Table | |
|
| 11 | [SID103222496] | Unspecified | Ki | 26900 | Compound tested for the inhibition of Gamma-glutamyltranspeptidase in rat kidney at pH 8.0 at 37 degree C (Competitive inhibition) [AID71712, Type: Literature] | | View X | Row No. | 11 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | Ki | 26900 [uM] | | BioAssay | Compound tested for the inhibition of Gamma-glutamyltranspeptidase in rat kidney at pH 8.0 at 37 degree C (Competitive inhibition) | | AID | 71712 | | BioAssay type | Literature | | Target | | | PubMed | 15177451 | | Data Table | |
|
| 12 | [SID103222496] | Unspecified | Ki | 150000 | Inhibition constant against Escherichia coli cyclopropane fatty acid synthase [AID71601, Type: Literature] | | View X | Row No. | 12 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | Ki | 150000 [uM] | | BioAssay | Inhibition constant against Escherichia coli cyclopropane fatty acid synthase | | AID | 71601 | | BioAssay type | Literature | | Target | | | PubMed | 15026045 | | Data Table | |
|
| 13 | [SID103222496] | Unspecified | | | Substrate level that produces half the maximal velocity(M-T) of rat methionine adenosyl transferase [AID34138, Type: Literature] | | View X | Row No. | 13 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Substrate level that produces half the maximal velocity(M-T) of rat methionine adenosyl transferase | | AID | 34138 | | BioAssay type | Literature | | Target | | | PubMed | 3755757 | | Data Table | |
|
| 14 | [SID103222496] | Unspecified | | | Calculated partition coefficient (clogP) [AID16315, Type: other] | | View X | Row No. | 14 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Calculated partition coefficient (clogP) | | AID | 16315 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 15 | [SID103222496] | Unspecified | | | Cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 1 mg/ml after 30 hrs [AID401476, Type: other] | | View X | Row No. | 15 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 1 mg/ml after 30 hrs | | AID | 401476 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 16 | [SID103222496] | Unspecified | | | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature] | | View X | Row No. | 16 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans | | AID | 588211 | | BioAssay type | Literature | | Target | | | PubMed | 20014752 | | Data Table | |
|
| 17 | [SID103222496] | Unspecified | | | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature] | | View X | Row No. | 17 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents | | AID | 588212 | | BioAssay type | Literature | | Target | | | PubMed | 20014752 | | Data Table | |
|
| 18 | [SID103222496] | Unspecified | | | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature] | | View X | Row No. | 18 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents | | AID | 588213 | | BioAssay type | Literature | | Target | | | PubMed | 20014752 | | Data Table | |
|
| 19 | [SID103222496] | Unspecified | | | Ratio of Kcat to Km for Salinispora tropica CNB-440 wild type recombinant SalL expressed in Escherichia coli BL21(DE3) for formation of S-Adenosyl methionine [AID498934, Type: Literature] | | View X | Row No. | 19 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Ratio of Kcat to Km for Salinispora tropica CNB-440 wild type recombinant SalL expressed in Escherichia coli BL21(DE3) for formation of S-Adenosyl methionine | | AID | 498934 | | BioAssay type | Literature | | Target | | | PubMed | 18059261 | | Data Table | |
|
| 20 | [SID103222496] | Unspecified | | | Ratio of relative Vmax of normal tissue (M-2) form of rat methionine Adenosyltransferase to that of KM of normal tissue(M-2)form of rat methionine Adenosyltransferase [AID230503, Type: Literature] | | View X | Row No. | 20 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Ratio of relative Vmax of normal tissue (M-2) form of rat methionine Adenosyltransferase to that of KM of normal tissue(M-2)form of rat methionine Adenosyltransferase | | AID | 230503 | | BioAssay type | Literature | | Target | | | PubMed | 3755757 | | Data Table | |
|
| 21 | [SID103222496] | Unspecified | | | Ratio of Vmax of normal tissue (M-T) form of rat methionine Adenosyltransferase to that of KM of normal tissue(M-T)form of rat methionine Adenosyltransferase [AID230665, Type: Literature] | | View X | Row No. | 21 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Ratio of Vmax of normal tissue (M-T) form of rat methionine Adenosyltransferase to that of KM of normal tissue(M-T)form of rat methionine Adenosyltransferase | | AID | 230665 | | BioAssay type | Literature | | Target | | | PubMed | 3755757 | | Data Table | |
|
| 22 | [SID103222496] | Unspecified | | | Bitter threshold value of the compound; S denotes 'Sulfurous' [AID233322, Type: Literature] | | View X | Row No. | 22 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Bitter threshold value of the compound; S denotes 'Sulfurous' | | AID | 233322 | | BioAssay type | Literature | | Target | | | PubMed | 3656360 | | Data Table | |
|
| 23 | [SID103222496] | Unspecified | | | Antihepatotoxic activity against 1.5 hrs galactosamine pretreatment-induced cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 0.01 mg/ml after 30 hrs relative to control [AID401471, Type: other] | | View X | Row No. | 23 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Antihepatotoxic activity against 1.5 hrs galactosamine pretreatment-induced cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 0.01 mg/ml after 30 hrs relative to control | | AID | 401471 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 24 | [SID103222496] | Unspecified | | | Antihepatotoxic activity against 1.5 hrs galactosamine pretreatment-induced cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 0.1 mg/ml after 30 hrs relative to control [AID401472, Type: other] | | View X | Row No. | 24 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Antihepatotoxic activity against 1.5 hrs galactosamine pretreatment-induced cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 0.1 mg/ml after 30 hrs relative to control | | AID | 401472 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 25 | [SID103222496] | Unspecified | | | Antihepatotoxic activity against 1.5 hrs galactosamine pretreatment-induced cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 1 mg/ml after 30 hrs relative to control [AID401473, Type: other] | | View X | Row No. | 25 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Antihepatotoxic activity against 1.5 hrs galactosamine pretreatment-induced cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 1 mg/ml after 30 hrs relative to control | | AID | 401473 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 26 | [SID103222496] | Unspecified | | | Cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 0.01 mg/ml after 30 hrs [AID401474, Type: other] | | View X | Row No. | 26 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 0.01 mg/ml after 30 hrs | | AID | 401474 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 27 | [SID103222496] | Unspecified | | | Cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 0.1 mg/ml after 30 hrs [AID401475, Type: other] | | View X | Row No. | 27 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Cytotoxicity in Wistar rat hepatocytes assessed as glutamic-pyruvic transaminase activity at 0.1 mg/ml after 30 hrs | | AID | 401475 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 28 | [SID103222496] | Unspecified | | | Partition coefficient (logP) [AID26797, Type: Literature] | | View X | Row No. | 28 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Partition coefficient (logP) | | AID | 26797 | | BioAssay type | Literature | | Target | | | PubMed | 3656360 | | Data Table | |
|
| 29 | [SID103222496] | Unspecified | | | Activity at Salinispora tropica CNB-440 wild type recombinant SalL expressed in Escherichia coli BL21(DE3) assessed as formation of S-Adenosyl methionine after 30 mins by HPLC analysis [AID498932, Type: Literature] | | View X | Row No. | 29 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | BioAssay | Activity at Salinispora tropica CNB-440 wild type recombinant SalL expressed in Escherichia coli BL21(DE3) assessed as formation of S-Adenosyl methionine after 30 mins by HPLC analysis | | AID | 498932 | | BioAssay type | Literature | | Target | | | PubMed | 18059261 | | Data Table | |
|
| 30 | [SID103222496] | Unspecified | Ki | | TP_TRANSPORTER: inhibition of L-tryptophan uptake in Xenopus laevis oocytes [AID681113, Type: other] | Monocarboxylate transporter 10 [gi:81871541] | View X | Row No. | 30 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Unspecified | | Ki | [uM] | | BioAssay | TP_TRANSPORTER: inhibition of L-tryptophan uptake in Xenopus laevis oocytes | | AID | 681113 | | BioAssay type | other | | Target | Monocarboxylate transporter 10 [gi:81871541] | | PubMed | | | Data Table | |
|
| 31 | [SID103222496] | Inconclusive | Ki | | Inhibition of ferrous substituted Bacillus subtilis LuxS [AID264586, Type: Literature] | S-ribosylhomocysteine lyase [gi:7387851] | View X | Row No. | 31 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Inconclusive | | Ki | [uM] | | BioAssay | Inhibition of ferrous substituted Bacillus subtilis LuxS | | AID | 264586 | | BioAssay type | Literature | | Target | S-ribosylhomocysteine lyase [gi:7387851] | | PubMed | 16686542 | | Data Table | |
|
| 32 | [SID103222496] | Inconclusive | Ki | | Inhibition of zinc substituted Bacillus subtilis LuxS [AID264587, Type: Literature] | S-ribosylhomocysteine lyase [gi:7387851] | View X | Row No. | 32 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Inconclusive | | Ki | [uM] | | BioAssay | Inhibition of zinc substituted Bacillus subtilis LuxS | | AID | 264587 | | BioAssay type | Literature | | Target | S-ribosylhomocysteine lyase [gi:7387851] | | PubMed | 16686542 | | Data Table | |
|
| 33 | [SID103222496] | Inconclusive | Ki | | Inhibition of cobalt substituted Escherichia coli LuxS [AID264584, Type: Literature] | | View X | Row No. | 33 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Inconclusive | | Ki | [uM] | | BioAssay | Inhibition of cobalt substituted Escherichia coli LuxS | | AID | 264584 | | BioAssay type | Literature | | Target | | | PubMed | 16686542 | | Data Table | |
|
| 34 | [SID103222496] | Inconclusive | Ki | | Inhibition of cobalt substituted Vibrio harveyi LuxS [AID264585, Type: Literature] | | View X | Row No. | 34 | | Structure |
| | Substance | | | SID | 103222496 | | CID | 6137 | | Outcome | Inconclusive | | Ki | [uM] | | BioAssay | Inhibition of cobalt substituted Vibrio harveyi LuxS | | AID | 264585 | | BioAssay type | Literature | | Target | | | PubMed | 16686542 | | Data Table | |
|
Chemical Probe 
Active 
Inactive 
Inconclusive 
Unspecified 
