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Methionine (CID 6137) - Compound BioActivity Data
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BioActivity Outcomes:
Active(15)
 
 
Inactive(7)
 
 
Inconclusive(4)
 
 
Unspecified(48)
 
 
Top Targets:
MetRS core(3)
 
 
MetAP2(3)
 
 
M28 SGAP like(3)
 
 
LuxS(3)
 
 
 
MFS(1)
 
 
BioAssay Types:
Literature(73)
 
 
 
 
 
BioActivity Types:
Ki(12)
 
 
 
 
Kd(2)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 68    Data Row: 74   Total Pages: 4   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103222496]
Km 5Michaelis constant (KM) was evaluated [AID17451, Type: Literature]
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2
[SID103222496]
Km 5Substrate activity with rat Methionine adenosyltransferase II [AID107897, Type: Literature]
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3
[SID46392872]
Kd 11Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Methionyl-Trna Synthetase From Escherichia Coli Complexed With Methionine And Adenosine [gi:46015206]
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4
[SID46392872]
Kd 11Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Methionyl-Trna Synthetase From Escherichia Coli Complexed With Methionine And Adenosine [gi:46015206]
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5
[SID103222496]
Km 15.6Substrate activity with normal tissue (M-T) form of rat methionine Adenosyltransferase [AID34131, Type: Literature]
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6
[SID46393022]
Ki 8700Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Streptomyces Griseus Aminopeptidase Complexed With Methionine [gi:7766866]
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7
[SID46393022]
Ki 8700Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Streptomyces Griseus Aminopeptidase Complexed With Methionine [gi:7766866]
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8
[SID46393499]
Ki 150000Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, The Product Bound Form Of The Mn(Ii)loaded Methionine Aminopeptidase From Hyperthermophile Pyrococcus Furiosus [gi:61680215]
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9
[SID46393499]
Ki 150000Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, The Product Bound Form Of The Mn(Ii)loaded Methionine Aminopeptidase From Hyperthermophile Pyrococcus Furiosus [gi:61680215]
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10
[SID46393499]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, The Product Bound Form Of The Mn(Ii)loaded Methionine Aminopeptidase From Hyperthermophile Pyrococcus Furiosus [gi:61680215]
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11
[SID46392872]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Methionyl-Trna Synthetase From Escherichia Coli Complexed With Methionine And Adenosine [gi:46015206]
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12
[SID103222496]
Induction of disease resistance in Oryza sativa Nipponbare (rice) assessed as increase in momilactone level in press-injured leaves at 7 mM pretreated with water 24 hr prior to compound treatment measured after 8 to 10 hr by HPLC-MS-MS analysis relative to control [AID1100831, Type: Literature]
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13
[SID103222496]
Induction of disease resistance in Oryza sativa Nipponbare (rice) assessed as increase in sakuranetin level in press-injured leaves at 7 mM pretreated with water 24 hr prior to compound treatment measured after 8 to 10 hr by HPLC-MS-MS analysis relative to control [AID1100833, Type: Literature]
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14
[SID103222496]
Induction of disease resistance in Oryza sativa Nipponbare (rice) assessed as increase in naringenin 7-O-methyltransferase activity in press-injured leaves at 7 mM by spectrophotometric analysis relative to control [AID1100840, Type: Literature]
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15
[SID46393022]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Streptomyces Griseus Aminopeptidase Complexed With Methionine [gi:7766866]
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16
[SID103222496]
Ki 61Inhibition of cobalt substituted Bacillus subtilis LuxS [AID264583, Type: Literature]S-ribosylhomocysteine lyase [gi:7387851]
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17
[SID103222496]
Km 70Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liver [AID200229, Type: Literature]
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18
[SID103222496]
EC50 800Concentration required for obtaining 50% of the fluorescence intensity of copper-free calcein 1, in bovine serum albumin [AID51033, Type: Literature]
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19
[SID103222496]
Km 2600Effect on Salinispora tropica CNB-440 wild type recombinant SalL expressed in Escherichia coli BL21(DE3)-mediated S-Adenosyl methionine formation after 30 mins by HPLC analysis [AID498933, Type: Literature]
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20
[SID103222496]
Ki 26900Compound tested for the inhibition of Gamma-glutamyltranspeptidase in rat kidney at pH 8.0 at 37 degree C (Competitive inhibition) [AID71712, Type: Literature]
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