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Lactose (CID 6134) - Compound BioActivity Data
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BioActivity Outcomes:
Active(24)
 
 
Inactive(84)
 
 
Inconclusive(3)
 
 
Unspecified(44)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
GLECT(6)
 
 
lectin legume..(6)
 
 
BioAssay Types:
Literature(65)
 
 
 
 
Confirmatory(62)
 
 
 
Summary(24)
 
 
 
BioActivity Types:
Potency(80)
 
 
 
Kd(17)
 
 
 
IC50(13)
 
 
 
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 143    Data Row: 155   Total Pages: 8   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104234182]
Kd 23Binding affinity to galectin 9N terminal domain at 0 degC by fluorescence polarization assay [AID412879, Type: Literature]
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2
[SID104234182]
IC50 45Inhibitory concentration against Escherichia coli heat-labile enterotoxin (LT) binding to ganglioside GD1b was determined by ELISA assay [AID71736, Type: Literature]
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3
[SID46393700]
Kd 77Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Structure Of Phanerochaete Chrysosporium Cellobiohydrolase Cel7d (Cbh58) In Complex With Lactose [gi:66361309]
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4
[SID46393700]
Kd 77Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Structure Of Phanerochaete Chrysosporium Cellobiohydrolase Cel7d (Cbh58) In Complex With Lactose [gi:66361309]
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5
[SID170481250]
Kd 260Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Human Galectin-3 Carbohydrate-Recognition Domain With Lactose Bound, At 1.35 Angstrom Resolution [gi:134104938]
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6
[SID170481250]
Kd 260Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Human Galectin-3 Carbohydrate-Recognition Domain With Lactose Bound, At 1.35 Angstrom Resolution [gi:134104938]
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7
[SID46392060]
Kd 320Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, High-Resolution Crystal Structure Of Erythrina Cristagalli Lectin In Complex With Lactose [gi:21730304]
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8
[SID46392060]
Kd 320Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, High-Resolution Crystal Structure Of Erythrina Cristagalli Lectin In Complex With Lactose [gi:21730304]
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9
[SID46391476]
Kd 515Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Erythrina Corallodendron Lectin In Complex With Lactose [gi:157830124]
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10
[SID46391476]
Kd 515Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Erythrina Corallodendron Lectin In Complex With Lactose [gi:157830124]
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11
[SID46392050]
Kd 2680Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Alpha-,1,3 Galactosyltransferase - Lactose Complex [gi:29726233]
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12
[SID170481920]
Ki 16400Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Recombinant Agrocybe Aegerita Lectin,Raal, Complex With Lactose [gi:221046521]
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13
[SID170481920]
Ki 16400Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Recombinant Agrocybe Aegerita Lectin,Raal, Complex With Lactose [gi:221046521]
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14
[SID46391476]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Erythrina Corallodendron Lectin In Complex With Lactose [gi:157830124]
View
15
[SID46392060]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, High-Resolution Crystal Structure Of Erythrina Cristagalli Lectin In Complex With Lactose [gi:21730304]
View
16
[SID46393700]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Structure Of Phanerochaete Chrysosporium Cellobiohydrolase Cel7d (Cbh58) In Complex With Lactose [gi:66361309]
View
17
[SID46392050]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: other]Chain A, Alpha-,1,3 Galactosyltransferase - Lactose Complex [gi:29726233]
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18
[SID48416152]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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19
[SID104234182]
Reduction of CD45 co-localization with GM1-enriched microdomain in human Jurkat T cells after 3 days [AID381563, Type: Literature]
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20
[SID104234182]
Induction of Nck protein binding to TCR complex in human Jurkat T cells by immunoprecipitation [AID381590, Type: Literature]
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