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octyl gallate (CID 61253) - Compound BioActivity Data
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BioActivity Outcomes:
Active(51)
 
 
Inactive(43)
 
 
Inconclusive(45)
 
 
Unspecified(60)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD ER(9)
 
 
 
 
GT1 Gtf like(7)
 
 
NR LBD TR(7)
 
 
 
 
BioAssay Types:
Confirmatory(93)
 
 
 
 
Literature(66)
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(111)
 
 
 
 
IC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 191    Data Row: 199   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210592]
Potency-Replicate_1 0.5448qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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2
[SID144210592]
Potency-Replicate_1 0.6113qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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3
[SID103179230]
IC50 0.83Inhibition of C-terminal hexahistidine-tagged rat recombinant squalene epoxidase without N-terminal putative membrane domain expressed in Escherichia coli [AID357307, Type: Literature]Squalene monooxygenase [gi:1706689]
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4
[SID103179230]
IC50 1Cytotoxicity against mouse L929 cells [AID732052, Type: Literature]
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5
[SID144210592]
Potency-Replicate_1 1.3685qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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6
[SID103179230]
IC50 1.5Cytotoxicity against mouse WEHI231 cells [AID732053, Type: Literature]
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7
[SID144210592]
Potency-Replicate_1 1.9331qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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8
[SID144210592]
Potency-Replicate_1 2.169qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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9
[SID144210592]
Ratio Potency (uM) 3.21043qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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10
[SID144210592]
Potency-Replicate_1 3.8895qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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11
[SID144210592]
Potency-Replicate_1 6.1131qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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12
[SID144210592]
AR Potency (uM) 7.40614qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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13
[SID144210592]
Potency-Replicate_1 7.6959qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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14
[SID144210592]
Potency-Replicate_1 13.6854qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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15
[SID26757543]
Potency 14.1254qHTS assay for small molecule antagonists of androgen receptor signaling [AID588516, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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16
[SID103179230]
IC50 18.6Inhibitory activity against lipid peroxidation of egg-phosphatidylcholine (PC) liposome caused by water-soluble radical initiator [2,2'-azobis(2-amidinopropane) dihydrochloride] (AAPH) [AID68587, Type: Literature]
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17
[SID103179230]
IC50 22Cytotoxicity against mouse L1210 cells [AID732048, Type: Literature]
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18
[SID144210592]
Potency-Replicate_1 24.5412qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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19
[SID144210592]
Potency-Replicate_1 27.5357qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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20
[SID144210592]
Potency-Replicate_1 34.3762qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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