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octyl gallate (CID 61253) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(52)
 
 
Inactive(41)
 
 
Inconclusive(44)
 
 
Unspecified(57)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD ER(9)
 
 
 
 
GT1 Gtf like(7)
 
 
NR LBD TR(7)
 
 
 
 
BioAssay Types:
Confirmatory(93)
 
 
 
 
Literature(61)
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(111)
 
 
 
 
IC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 186    Data Row: 194   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210592]
Potency-Replicate_1 0.5448qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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2
[SID144210592]
Potency-Replicate_1 0.6113qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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3
[SID103179230]
IC50 0.83Inhibition of C-terminal hexahistidine-tagged rat recombinant squalene epoxidase without N-terminal putative membrane domain expressed in Escherichia coli [AID357307, Type: Literature]Squalene monooxygenase [gi:1706689]
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4
[SID103179230]
IC50 1Cytotoxicity against mouse L929 cells [AID732052, Type: Literature]
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5
[SID144210592]
Potency-Replicate_1 1.3685qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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6
[SID103179230]
IC50 1.5Cytotoxicity against mouse WEHI231 cells [AID732053, Type: Literature]
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7
[SID144210592]
Potency-Replicate_1 1.9331qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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8
[SID144210592]
Potency-Replicate_1 2.169qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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9
[SID144210592]
Ratio Potency (uM) 3.21043qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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10
[SID144210592]
Potency-Replicate_1 3.8895qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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11
[SID144210592]
Potency-Replicate_1 6.1131qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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12
[SID144210592]
AR Potency (uM) 7.40614qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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13
[SID144210592]
Potency-Replicate_1 7.6959qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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14
[SID144210592]
Potency-Replicate_1 13.6854qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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15
[SID26757543]
Potency 14.1254qHTS assay for small molecule antagonists of androgen receptor signaling [AID588516, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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16
[SID103179230]
IC50 18.6Inhibitory activity against lipid peroxidation of egg-phosphatidylcholine (PC) liposome caused by water-soluble radical initiator [2,2'-azobis(2-amidinopropane) dihydrochloride] (AAPH) [AID68587, Type: Literature]
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17
[SID103179230]
IC50 22Cytotoxicity against mouse L1210 cells [AID732048, Type: Literature]
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18
[SID144210592]
Potency-Replicate_1 24.5412qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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19
[SID144210592]
Potency-Replicate_1 24.5412qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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20
[SID144210592]
Potency-Replicate_1 27.5357qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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21
[SID144210592]
Potency-Replicate_1 27.5357qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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22
[SID144210592]
Potency-Replicate_1 27.5357qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743217, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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23
[SID144210592]
Potency-Replicate_1 34.3762qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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24
[SID144210592]
Potency-Replicate_1 43.6412qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743215, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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25
[SID144210592]
Potency-Replicate_1 43.6412qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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26
[SID144210592]
Potency-Replicate_1 43.6412qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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27
[SID103179230]
IC50 45Cytotoxicity against mouse B16F10 cells [AID732050, Type: Literature]
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28
[SID144210592]
Potency-Replicate_1 48.5577qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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29
[SID144210592]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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30
[SID144210592]
Potency-Replicate_1 54.4827qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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31
[SID144210592]
Potency-Replicate_1 54.4827qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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32
[SID144210592]
Potency-Replicate_1 54.4827qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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33
[SID144210592]
Potency-Replicate_1 54.941qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway [AID743223, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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34
[SID144210592]
Ratio Potency (uM) 59.3239qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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35
[SID144210592]
Ratio Potency (uM) 61.1306qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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36
[SID144210592]
Potency-Replicate_1 61.1306qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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37
[SID144210592]
Potency-Replicate_1 61.6448qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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38
[SID401614]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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39
[SID401614]
NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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40
[SID401614]
NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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41
[SID401614]
NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
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42
[SID401614]
NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
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43
[SID401614]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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44
[SID26757543]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_5, Type: other]
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45
[SID26757543]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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46
[SID26757543]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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47
[SID26757543]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_8, Type: other]
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48
[SID144210592]
AhR Potency (uM) qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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49
[SID26757543]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
View
50
[SID26757543]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
View