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8-Hydroxyquinoline citrate (CID 61080) - Compound BioActivity Data
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BioActivity Outcomes:
Active(23)
 
 
Inactive(37)
 
 
Inconclusive(26)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
NR LBD Fxr(4)
 
 
NR LBD VDR(4)
 
 
 
 
BioAssay Types:
Confirmatory(62)
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(80)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 86    Data Row: 86   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144212693]
Ratio Potency (uM) 0.0698069qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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2
[SID144212693]
Potency-Replicate_1 0.2477qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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3
[SID144212693]
Potency-Replicate_1 0.3118qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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4
[SID144212693]
Potency-Replicate_1 0.347qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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5
[SID144212693]
Potency-Replicate_1 0.3894qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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6
[SID144212693]
Potency-Replicate_1 0.4405qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743215, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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7
[SID144212693]
Potency-Replicate_1 0.55qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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8
[SID144212693]
Potency-Replicate_1 0.5545qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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9
[SID144212693]
Potency-Replicate_1 0.6981qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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10
[SID144212693]
Potency-Replicate_1 0.986qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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11
[SID144212693]
Potency-Replicate_1 1.3928qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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12
[SID144212693]
Potency-Replicate_1 2.7565qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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13
[SID144212693]
Potency-Replicate_1 3.4703qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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14
[SID144212693]
Potency-Replicate_1 4.3688qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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15
[SID144212693]
Potency-Replicate_1 4.9019qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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16
[SID144212693]
Potency-Replicate_1 8.7169qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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17
[SID144212693]
Potency-Replicate_1 8.7169qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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18
[SID144212693]
Potency-Replicate_1 8.7882qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway [AID743223, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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19
[SID144212693]
Potency-Replicate_1 9.7806qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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20
[SID144212693]
Potency-Replicate_1 15.5011qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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