Bookmark and Share
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole (CID 6095481) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(58)
 
 
Inactive(776)
 
 
Inconclusive(105)
 
 
Unspecified(34)
 
 
Top Targets:
7tm 4(45)
 
 
 
NR LBD ER(24)
 
 
 
 
 
TRP 2(20)
 
 
 
p450(12)
 
 
 
G-alpha(10)
 
 
 
BioAssay Types:
Confirmatory(500)
 
 
 
 
 
Screening(381)
 
 
 
 
Literature(54)
 
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(399)
 
 
 
 
 
IC50(38)
 
 
 
 
EC50(13)
 
 
 
AC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 763    Data Row: 973   Total Pages: 49   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103357561]
EC50 0.0001Activation of human ERalpha expressed in human U2-OS cells by luciferase reporter gene assay relative to untreated control [AID707063, Type: Literature]Estrogen receptor [gi:544257]
View
2
[SID103357561]
EC50 0.003Activation of ERalpha in human MCF7/2a cells by luciferase reporter gene assay relative to untreated control [AID707065, Type: Literature]Estrogen receptor [gi:544257]
View
3
[SID26752190]
Potency 0.0112qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
4
[SID90341714]
Potency 0.2908qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
5
[SID50104850]
Potency 1.9953Validation screen for inhibitors of Lassa infection [AID463096, Type: confirmatory]
View
6
[SID50104850]
Potency 1.9953qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
7
[SID90341714]
Potency 2.0596qHTS for Activators of Parkin Expression: LOPAC Validation Assay (NLuc Reporter) [AID720572, Type: confirmatory]Parkin [Homo sapiens] [gi:3063388]
View
8
[SID11114080]
Potency 2.5119qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
9
[SID26732630]
AC50_uM 2.916Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Inhibitors of DnaB-Intein Splicing Activity [AID449749, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
View
10
[SID11111273]
Potency 3.1623qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9 [AID883, Type: confirmatory]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
View
11
[SID11111273]
Potency 3.1623qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [Homo sapiens] [gi:32879895]
View
12
[SID11114080]
Potency 3.1623qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View
13
[SID11114080]
Potency 3.1623qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
View
14
[SID26732630]
AC50_uM 3.781Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Cancer Stem Cells [AID449748, Type: confirmatory]
View
15
[SID26732630]
AC50_uM 4.366Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Non-Covalent Inhibitors of RecA-Intein Splicing Activity [AID449750, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
View
16
[SID26732630]
EC50_uM 4.88Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity [AID435010, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
View
17
[SID26732630]
AC50_uM 6.097Dose Response HTS Screen to Identify Cytotoxic Compounds of HMLE_sh_eGFP [AID463074, Type: confirmatory]
View
18
[SID103357561]
IC50 6.30957Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
View
19
[SID11111273]
Potency 10qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
View
20
[SID11111273]
Potency 10qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View