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Methicillin (CID 6087) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(10)
 
 
Inconclusive(2)
 
 
Unspecified(123)
 
 
Top Targets:
NAD binding 8(1)
 
 
Bcl-2 like(1)
 
 
STKc AGC(1)
 
 
COG2602(1)
 
 
DUF3371(1)
 
 
BioAssay Types:
Literature(104)
 
 
 
 
 
Screening(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 139    Data Row: 139   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179197]
MIC 1Antibacterial activity against Staphylococcus aureus ATCC 29213 [AID288606, Type: Literature]
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2
[SID103179197]
MIC 3.13Antibacterial activity against Staphylococcus aureus ATCC 29213 after 16 to 20 hrs by microdilution susceptibility test [AID460794, Type: Literature]
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3
[SID103179197]
MIC 32Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 [AID288607, Type: Literature]
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4
[SID48416243]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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5
[SID103179197]
MIC 400Antibacterial activity against methicillin-resistant Staphylococcus aureus BAA-44 after 16 to 20 hrs by microdilution susceptibility test [AID460793, Type: Literature]
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6
[SID103179197]
Inhibition of beta-lactamase of Enterobacter aerogenes relative to oxacillin sulfoxide(=1) [AID43270, Type: Literature]Beta-lactamase OXA-9 [gi:166214909]
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7
[SID103179197]
Antibacterial activity against Staphylococcus aureus by NCCLS method [AID467876, Type: Literature]
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8
[SID103179197]
Volume of distribution at steady state in human after iv administration [AID540209, Type: Literature]
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9
[SID103179197]
Clearance in human after iv administration [AID540210, Type: Literature]
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10
[SID103179197]
Fraction unbound in human after iv administration [AID540211, Type: Literature]
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11
[SID103179197]
Mean residence time in human after iv administration [AID540212, Type: Literature]
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12
[SID103179197]
Half life in human after iv administration [AID540213, Type: Literature]
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13
[SID103179197]
Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 24 hrs by Etest [AID548253, Type: Literature]
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14
[SID103179197]
Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 24 hrs by Etest [AID548254, Type: Literature]
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15
[SID103179197]
Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 24 hrs by Etest [AID548255, Type: Literature]
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16
[SID103179197]
Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 24 hrs by Etest [AID548256, Type: Literature]
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17
[SID103179197]
Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 24 hrs by Etest [AID548257, Type: Literature]
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18
[SID103179197]
Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 48 hrs by Etest [AID548471, Type: Literature]
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19
[SID103179197]
Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 48 hrs by Etest [AID548472, Type: Literature]
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20
[SID103179197]
Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 48 hrs by Etest [AID548473, Type: Literature]
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21
[SID103179197]
Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 48 hrs by Etest [AID548474, Type: Literature]
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22
[SID103179197]
Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 48 hrs by Etest [AID548475, Type: Literature]
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23
[SID103179197]
Antibacterial activity against 10'7 CFU/ml wild-type Listeria monocytogenes EGD-e Serovar 1/2a at 5 ug after 16 hrs by disk diffusion assay [AID577512, Type: Literature]
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24
[SID103179197]
Antibacterial activity against 10'7 CFU/ml telA-deficient Listeria monocytogenes EGD-e Serovar 1/2a at 5 ug after 16 hrs by disk diffusion assay [AID577709, Type: Literature]
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25
[SID103179197]
Antimicrobial activity against multidrug-resistant Staphylococcus aureus after 18 hrs by agar dilution method [AID591660, Type: Literature]
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26
[SID103179197]
Antibacterial activity against Staphylococcus aureus ATCC 25923 by microdilution method [AID324017, Type: Literature]
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27
[SID103179197]
Antibacterial activity against Staphylococcus aureus 33591 by microdilution method [AID324018, Type: Literature]
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28
[SID103179197]
Antibacterial activity against Staphylococcus aureus 31005 by microdilution method [AID324019, Type: Literature]
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29
[SID103179197]
Antibacterial activity against methicillin-resistant Staphylococcus aureus by microdilution method [AID324020, Type: Literature]
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30
[SID103179197]
Antibacterial activity against Staphylococcus aureus Smith by microdilution method [AID324021, Type: Literature]
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31
[SID103179197]
Antibacterial activity against Staphylococcus aureus 307109 by microdilution method [AID324022, Type: Literature]
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32
[SID103179197]
Antimicrobial activity against Escherichia coli DC2 by twofold serial microbroth dilution method [AID355387, Type: Literature]
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33
[SID103179197]
Antimicrobial activity against Escherichia coli UB1005 by twofold serial microbroth dilution method [AID355388, Type: Literature]
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34
[SID103179197]
Antimicrobial activity against Pseudomonas aeruginosa K799 by twofold serial microbroth dilution method [AID355389, Type: Literature]
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35
[SID103179197]
Antimicrobial activity against Pseudomonas aeruginosa Z61 by twofold serial microbroth dilution method [AID355390, Type: Literature]
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36
[SID103179197]
Antimicrobial activity against methicillin-resistant Staphylococcus aureus SAP00017 by twofold serial microbroth dilution method [AID355391, Type: Literature]
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37
[SID103179197]
Antimicrobial activity against methicillin-susceptible Staphylococcus aureus RN4220 by twofold serial microbroth dilution method [AID355392, Type: Literature]
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38
[SID103179197]
Antimicrobial activity against Bacillus subtilis UBC221 by twofold serial microbroth dilution method [AID355393, Type: Literature]
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39
[SID103179197]
Antimicrobial activity against Candida albicans UBC54 by twofold serial microbroth dilution method [AID355394, Type: Literature]
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40
[SID103179197]
Bactericidal activity against methicillin-resistant Staphylococcus aureus SA2 by microdilution technique [AID368276, Type: Literature]
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41
[SID103179197]
Bactericidal activity against vancomycin-intermediate Staphylococcus aureus by microdilution technique [AID368277, Type: Literature]
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42
[SID103179197]
Antimicrobial activity against Staphylococcus aureus SAP00017 after 24 hrs by twofold serial microbroth dilution assay [AID400279, Type: Literature]
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43
[SID103179197]
Antimicrobial activity against Staphylococcus aureus RN4220 after 24 hrs by twofold serial microbroth dilution assay [AID400280, Type: Literature]
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44
[SID103179197]
Antimicrobial activity against Bacillus subtilis Vernon after 24 hrs by twofold serial microbroth dilution assay [AID400281, Type: Literature]
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45
[SID103179197]
Antimicrobial activity against Candida albicans CAND105 after 48 hrs by twofold serial microbroth dilution assay [AID400282, Type: Literature]
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46
[SID103179197]
Antimicrobial activity against Escherichia coli UB1005 after 24 hrs by twofold serial microbroth dilution assay [AID401031, Type: Literature]
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47
[SID103179197]
Antimicrobial activity against Escherichia coli DC2 after 24 hrs by twofold serial microbroth dilution assay [AID401032, Type: Literature]
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48
[SID103179197]
Antimicrobial activity against Pseudomonas aeruginosa K799 after 24 hrs by twofold serial microbroth dilution assay [AID401033, Type: Literature]
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49
[SID103179197]
Antimicrobial activity against Pseudomonas aeruginosa Z61 after 24 hrs by twofold serial microbroth dilution assay [AID401034, Type: Literature]
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50
[SID103179197]
Total body clearance in human [AID425652, Type: Literature]
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