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BioActivity Data for Compound Methicillin (CID 6087)

BioActivity Outcomes:
Active(5)
 
 
Inactive(10)
 
 
Inconclusive(2)
 
 
Unspecified(158)
 
 
Top Targets:
Bcl-2 like(1)
 
 
DUF3371(1)
 
 
NAD binding 8(1)
 
 
STKc STK33(1)
 
 
YbxI(1)
 
 
BioAssay Types:
Literature(133)
 
 
 
 
 
Screening(8)
 
 
BioAssay Categories:
In vitro(17)
 
 
In vivo(6)
 
 
Biochemical(3)
 
 
 
Toxicity(19)
 
 
ADME(7)
 
 
Cell-based(7)
 
 
Organism-base..(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 175    Data Row: 175   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179197]
Antibacterial activity against Staphylococcus aureus ATCC 29213 after 16 to 20 hrs by microdilution susceptibility test [AID460794, Type: Literature]
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2
[SID103179197]
Antibacterial activity against Staphylococcus epidermidis RP62A assessed as growth inhibition after 12 hr by CLSI broth microdilution method [AID1115438, Type: other]
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3
[SID103179197]
Antibacterial activity against Staphylococcus aureus ATCC 29213 [AID288606, Type: Literature]
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4
[SID103179197]
Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 [AID288607, Type: Literature]
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5
[SID48416243]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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6
[SID103179197]
Inhibition of beta-lactamase of Enterobacter aerogenes relative to oxacillin sulfoxide(=1) [AID43270, Type: Literature]Beta-lactamase OXA-9 [gi:166214909]
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7
[SID103179197]
Antimicrobial activity against multidrug-resistant Staphylococcus aureus after 18 hrs by agar dilution method [AID591660, Type: Literature]
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8
[SID103179197]
Antibacterial activity against 10'7 CFU/ml telA-deficient Listeria monocytogenes EGD-e Serovar 1/2a at 5 ug after 16 hrs by disk diffusion assay [AID577709, Type: Literature]
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9
[SID103179197]
Antibacterial activity against 10'7 CFU/ml wild-type Listeria monocytogenes EGD-e Serovar 1/2a at 5 ug after 16 hrs by disk diffusion assay [AID577512, Type: Literature]
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10
[SID103179197]
Half life in human after iv administration [AID540213, Type: Literature]
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11
[SID103179197]
Mean residence time in human after iv administration [AID540212, Type: Literature]
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12
[SID103179197]
Fraction unbound in human after iv administration [AID540211, Type: Literature]
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13
[SID103179197]
Clearance in human after iv administration [AID540210, Type: Literature]
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14
[SID103179197]
Antibacterial activity against Staphylococcus aureus assessed as growth inhibition at 5 ug/mL after 24 hrs [AID1060486, Type: Literature]
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15
[SID103179197]
Antibacterial activity against methicillin-resistant Staphylococcus aureus 8282 clinical isolate assessed as growth inhibition after 12 hr by CLSI broth microdilution method [AID1115435, Type: other]
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16
[SID103179197]
Antibacterial activity against Salmonella assessed as growth inhibition after 12 hr by CLSI broth microdilution method [AID1115436, Type: other]
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17
[SID103179197]
Antibacterial activity against Escherichia coli ATCC 25922 assessed as growth inhibition after 12 hr by CLSI broth microdilution method [AID1115437, Type: other]
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18
[SID103179197]
In vitro antimicrobial activity against Staphylococcus aureus X1.1 strain [AID201411, Type: Literature]
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19
[SID103179197]
Minimum inhibitory concentration against homoresistant strain of Staphylococcus aureus 447 in the absence of NaCl [AID201186, Type: Literature]
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20
[SID103179197]
Minimum inhibitory concentration against homoresistant strain of Staphylococcus aureus 447 in 4% of NaCl [AID201185, Type: Literature]
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