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Vedaclidine (CID 60868) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(3)
 
 
Unspecified(5)
 
 
BioAssay Types:
Literature(7)
 
 
 
BioActivity Types:
Ki(1)
 
 
IC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103375475]
Ki 0.0004Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortex [AID142221, Type: Literature]
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2
[SID103375475]
IC50 0.0022In vitro inhibition of [3H]Oxo-Mas binding to M1 and M4 receptors in rat brain homogenate. [AID142501, Type: Literature]
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3
[SID85214108]
Ligands of bioamine (Class A) GPCRs [AID2062, Type: other]
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4
[SID103375475]
Minimum intravenous effective dose required to inhibit jejunal motility in ferrets [AID71922, Type: Literature]
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5
[SID103375475]
Intravenous effective dose required to produce a 1 mV increase in transmural potential difference in ferrets (GI side effect) [AID71930, Type: Literature]
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6
[SID103375475]
Analgesic activity measured using mouse writhing antinociceptive assay after subcutaneous administration [AID128478, Type: Literature]
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7
[SID103375475]
Conditioned avoidance responding in rat after subcutaneous administration (3 mg/kg); expressed as avoidance response/response failure [AID169193, Type: Literature]
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8
[SID103375475]
Inhibition of conditioned avoidance response in rat following s.c. administration. [AID178179, Type: Literature]
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