Vedaclidine (CID 60868) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(3)
 
 
Unspecified(5)
 
 
BioAssay Types:
Literature(7)
 
 
 
BioActivity Types:
IC50(1)
 
 
Ki(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 8   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103375475]
Ki 0.0004Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortex [AID142221, Type: Literature]
View
2
[SID103375475]
IC50 0.0022In vitro inhibition of [3H]Oxo-Mas binding to M1 and M4 receptors in rat brain homogenate. [AID142501, Type: Literature]
View
3
[SID85214108]
 Ligands of bioamine (Class A) GPCRs [AID2062, Type: other]
View
4
[SID103375475]
 Analgesic activity measured using mouse writhing antinociceptive assay after subcutaneous administration [AID128478, Type: Literature]
View
5
[SID103375475]
 Conditioned avoidance responding in rat after subcutaneous administration (3 mg/kg); expressed as avoidance response/response failure [AID169193, Type: Literature]
View
6
[SID103375475]
 Inhibition of conditioned avoidance response in rat following s.c. administration. [AID178179, Type: Literature]
View
7
[SID103375475]
 Intravenous effective dose required to produce a 1 mV increase in transmural potential difference in ferrets (GI side effect) [AID71930, Type: Literature]
View
8
[SID103375475]
 Minimum intravenous effective dose required to inhibit jejunal motility in ferrets [AID71922, Type: Literature]
View