Bookmark and Share
Papaverine (CID 6084) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(64)
 
 
Inactive(1125)
 
 
Inconclusive(108)
 
 
Unspecified(18)
 
 
Top Targets:
7TM GPCR Srx(27)
 
 
 
7TM GPCR Srsx(25)
 
 
 
alkPPc(14)
 
 
NR LBD PPAR(14)
 
 
 
Tryp SPc(13)
 
 
BioAssay Types:
Screening(644)
 
 
 
 
Confirmatory(536)
 
 
 
 
 
Literature(25)
 
 
 
 
Summary(25)
 
 
 
 
BioActivity Types:
Potency(402)
 
 
 
 
 
IC50(57)
 
 
 
 
EC50(15)
 
 
 
AC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1102    Data Row: 1315   Total Pages: 27   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103307406]
ID50 0.019Inhibitory effect on the response of isolated ileum to transmural electrical stimulation in guinea pig (anti-TMS activity) was determined [AID79532, Type: Literature]
View
2
[SID26747626]
Potency 1.2589qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
3
[SID56422444]
AC50_uM 2.48Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Based System Using Plate Reader - 2134-01_Inhibitor_Dose_CherryPick_Activity [AID624132, Type: confirmatory]
View
4
[SID855961]
Potency 2.5119qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
5
[SID855961]
EC50_uM 3.01Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity [AID435010, Type: confirmatory]RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)] [Mycobacterium tuberculosis H37Rv] [gi:15609874]
View
6
[SID56422444]
Potency 3.1623qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
View
7
[SID170465687]
Ratio Potency (uM) 3.75751qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
View
8
[SID144203777]
Potency-Replicate_1 4.0303qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
9
[SID144203777]
ER Potency (uM) 4.18792qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
10
[SID144203777]
Potency-Replicate_1 4.522qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
11
[SID144203777]
Potency-Replicate_1 5.0738qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
12
[SID144203777]
Potency-Replicate_1 5.0738qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
13
[SID144203777]
Potency 5.0807qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
14
[SID855961]
AC50_uM 5.657Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Inhibitors of DnaB-Intein Splicing Activity [AID449749, Type: confirmatory]Probable replicative DNA helicase DnaB [Mycobacterium tuberculosis H37Rv] [gi:15607200]
View
15
[SID56422444]
Potency 5.8048qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
16
[SID855961]
EC50_uM 7.303Fluorescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of GFP Chromophore Formation [AID434968, Type: confirmatory]RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)] [Mycobacterium tuberculosis H37Rv] [gi:15609874]
View
17
[SID103307406]
IC50 7.94328Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
View
18
[SID56422444]
AC50_uM 8.06Shn3: Cytotox assay Measured in Cell-Based System Using Plate Reader - 2134-03_Inhibitor_Dose_CherryPick_Activity [AID624134, Type: confirmatory]
View
19
[SID26747626]
Potency 8.1995qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
20
[SID26747626]
Potency 8.1995qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
21
[SID855961]
EC50 8.857Luminescence Cell-Based Dose Confirmation HTS to Identify Inhibitors of Platelet Dense Granule Release [AID1889, Type: confirmatory]
View
22
[SID144203777]
Potency-Replicate_1 9.0226qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
23
[SID26747626]
Potency 10VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
View
24
[SID50106832]
Potency 14.1254qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
View
25
[SID56422444]
Potency 14.581Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
26
[SID56422444]
AC50_uM 20.83Shn3: Dual-Go Shn3RL cells Measured in Cell-Based System Using Plate Reader - 2134-02_Inhibitor_Dose_CherryPick_Activity [AID624133, Type: confirmatory]
View
27
[SID103307406]
IC50 21Antiviral activity against HCMV in MRC5 cells by plaque reduction assay [AID293734, Type: Literature]
View
28
[SID855961]
AC50_uM 22.03VEID(2) R110 Enzymatic Primary HTS to identify Inhibitors of Caspase 6 Measured in Biochemical System Using Plate Reader - 7052-01_Inhibitor_Dose_CherryPick_Activity [AID720632, Type: confirmatory]Caspase 6, apoptosis-related cysteine peptidase [Homo sapiens] [gi:13325293]
View
29
[SID26747626]
Potency 50.1187Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein [Homo sapiens] [gi:118600387]
View
30
[SID855961]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) [AID463073, Type: screening]protein-arginine deiminase type-4 [Homo sapiens] [gi:216548487]
View
31
[SID855961]
VEID(2) R110 Enzymatic Primary HTS to identify Inhibitors of Caspase 6 Measured in Biochemical System Using Plate Reader - 7052-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID686996, Type: screening]Caspase 6, apoptosis-related cysteine peptidase [Homo sapiens] [gi:13325293]
View
32
[SID855961]
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2) [AID686940, Type: screening]COUP transcription factor 2 isoform a [Homo sapiens] [gi:14149746]
View
33
[SID855961]
Fluorescence Cell-Free Homogenous Primary HTS to Identify Inhibitors of RecA Intein Splicing Activity [AID2221, Type: screening]RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)] [Mycobacterium tuberculosis H37Rv] [gi:15609874]
View
34
[SID855961]
YopH HTS [AID898, Type: screening]YopH [Yersinia enterocolitica] [gi:28373018]
View
35
[SID855961]
Fluorescence-based biochemical high throughput screening confirmation assay to identify inhibitors of Crimean-Congo Hemorrhagic Fever (CCHF) viral ovarian tumor domain protease (vOTU): Pep-AMC substrate [AID686976, Type: screening]putative polyprotein [Crimean-Congo hemorrhagic fever virus] [gi:76364066]
View
36
[SID855961]
Fluorescence-based biochemical high throughput screening primary assay to identify inhibitors of Crimean-Congo Hemorrhagic Fever (CCHF) viral ovarian tumor domain protease (vOTU): Pep-AMC substrate [AID651958, Type: screening]putative polyprotein [Crimean-Congo hemorrhagic fever virus] [gi:76364066]
View
37
[SID10321416]
MDR-1 [AID377, Type: other]multidrug resistance protein 1 [Homo sapiens] [gi:42741659]
View
38
[SID855961]
Primary HTS Assay for S1P3 Antagonists [AID485, Type: screening]sphingosine 1-phosphate receptor 3 [Homo sapiens] [gi:38788193]
View
39
[SID103307406]
Compound was tested for its binding affinity against nicotinic acetylcholine receptor by fluorimetry assay [AID145336, Type: other]
View
40
[SID103307406]
Compound was tested for its binding affinity against nicotinic acetylcholine receptor by spectrometry assay [AID145337, Type: other]
View
41
[SID103307406]
Compound was tested for its binding affinity against nicotinic acetylcholine receptor by fluorimetry assay [AID145338, Type: other]
View
42
[SID103307406]
Compound was tested for its binding affinity against nicotinic acetylcholine receptor by spectrometry assay [AID145339, Type: other]
View
43
[SID103307406]
Compound was tested for its binding affinity against nicotinic acetylcholine receptor by spectrometry assay [AID145341, Type: other]
View
44
[SID855961]
MLPCN Platelet Activation -Dense Granule Release [AID1663, Type: screening]
View
45
[SID855961]
Counterscreen for inhibitors of Janus kinase 2 mutant JAK2V617F: Cell-based high throughput assay to identify inhibitors of parental Ba/F3 cell viability. [AID1486, Type: screening]
View
46
[SID855961]
Allosteric Modulators of D1 Receptors: Secondary Assay 2 [AID647, Type: other]
View
47
[SID855961]
HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
View
48
[SID855961]
Allosteric Modulators of D1 Receptors: Primary Screen [AID641, Type: screening]
View
49
[SID855961]
Allosteric Modulators of D1 Receptors: Confirmation Screen [AID642, Type: other]
View
50
[SID855961]
Primary Cell Based High Throughput Screening Assay for Antagonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) [AID571, Type: screening]5-hydroxytryptamine receptor 1E [gi:112822]
View