aripiprazole (CID 60795) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(86)
 
 
Inactive(609)
 
 
Inconclusive(57)
 
 
Unspecified(85)
 
 
Top Targets:
7TM GPCR Srx(52)
 
 
 
 
7TM GPCR Srsx(15)
 
 
 
 
alkPPc(10)
 
 
Bcl-2 like(10)
 
 
G-alpha(7)
 
 
 
 
BioAssay Types:
Screening(398)
 
 
 
 
Confirmatory(218)
 
 
 
 
 
Literature(200)
 
 
 
 
 
BioActivity Types:
Potency(162)
 
 
 
 
 
IC50(43)
 
 
 
 
 
Ki(37)
 
 
 
 
EC50(10)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 726    Data Row: 837   Total Pages: 17   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103307946]
Ki 0.0004Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in Wistar rat hippocampus homogenate [AID457688, Type: Literature]5-hydroxytryptamine receptor 1A [gi:112812]
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2
[SID103307946]
Ki 0.0004Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in Wistar rat hippocampus homogenate [AID457688, Type: Literature]5-hydroxytryptamine receptor 1A [gi:112812]
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3
[SID103307946]
Ki 0.0008Displacement of [3H]SCH23390 from dopamine D1 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometry [AID492643, Type: Literature]D(1A) dopamine receptor [gi:118229]
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4
[SID103307946]
Ki 0.0008Displacement of [3H]spiperone from dopamine D2 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometry [AID410332, Type: Literature]D(2) dopamine receptor [gi:47117674]
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5
[SID103307946]
Ki 0.0008Binding affinity to 5-HT2A [AID616781, Type: Literature]
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6
[SID103307946]
Ki 0.001Displacement of [3H]nemonapride from D2-like receptor in Wistar rat striatum homogenate [AID457687, Type: Literature]
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7
[SID103307946]
Ki 0.0018Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cells [AID595495, Type: Literature]D(2) dopamine receptor [gi:118206]
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8
[SID103307946]
Ki 0.0018Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cells [AID595495, Type: Literature]D(2) dopamine receptor [gi:118206]
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9
[SID103307946]
Ki 0.0018Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cells [AID595495, Type: Literature]D(2) dopamine receptor [gi:118206]
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10
[SID103307946]
Ki 0.0018Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cells [AID595495, Type: Literature]D(2) dopamine receptor [gi:118206]
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11
[SID103307946]
Ki 0.0018Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cells [AID595495, Type: Literature]D(2) dopamine receptor [gi:118206]
View
12
[SID103307946]
Ki 0.0026Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cells [AID458632, Type: Literature]D(2) dopamine receptor [gi:118206]
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13
[SID103307946]
Ki 0.0026Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cells [AID458632, Type: Literature]D(2) dopamine receptor [gi:118206]
View
14
[SID103307946]
Ki 0.0026Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cells [AID458632, Type: Literature]D(2) dopamine receptor [gi:118206]
View
15
[SID103307946]
Ki 0.0026Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cells [AID458632, Type: Literature]D(2) dopamine receptor [gi:118206]
View
16
[SID103307946]
Ki 0.0026Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cells [AID458632, Type: Literature]D(2) dopamine receptor [gi:118206]
View
17
[SID103307946]
Ki 0.0028Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cells [AID458633, Type: Literature]D(2) dopamine receptor [gi:118206]
View
18
[SID103307946]
Ki 0.0028Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cells [AID458633, Type: Literature]D(2) dopamine receptor [gi:118206]
View
19
[SID103307946]
Ki 0.0028Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cells [AID458633, Type: Literature]D(2) dopamine receptor [gi:118206]
View
20
[SID103307946]
Ki 0.0028Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cells [AID458633, Type: Literature]D(2) dopamine receptor [gi:118206]
View
21
[SID103307946]
Ki 0.0028Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cells [AID458633, Type: Literature]D(2) dopamine receptor [gi:118206]
View
22
[SID103307946]
Ki 0.0031Displacement of [125I]ABN from human recombinant D2L receptor expressed in HEK cells after 60 mins by gamma counter [AID610678, Type: Literature]D(2) dopamine receptor [gi:118206]
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23
[SID103307946]
Ki 0.0031Displacement of [125I]ABN from human recombinant D2L receptor expressed in HEK cells after 60 mins by gamma counter [AID610678, Type: Literature]D(2) dopamine receptor [gi:118206]
View
24
[SID103307946]
Ki 0.0031Displacement of [125I]ABN from human recombinant D2L receptor expressed in HEK cells after 60 mins by gamma counter [AID610678, Type: Literature]D(2) dopamine receptor [gi:118206]
View
25
[SID103307946]
Ki 0.0031Displacement of [125I]ABN from human recombinant D2L receptor expressed in HEK cells after 60 mins by gamma counter [AID610678, Type: Literature]D(2) dopamine receptor [gi:118206]
View
26
[SID103307946]
Ki 0.0031Displacement of [125I]ABN from human recombinant D2L receptor expressed in HEK cells after 60 mins by gamma counter [AID610678, Type: Literature]D(2) dopamine receptor [gi:118206]
View
27
[SID103307946]
Ki 0.0033Displacement of [3H]7OH-DPAT from dopamine D3 receptor expressed in Sf9 cells by scintillation spectrometry [AID410333, Type: Literature]
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28
[SID103307946]
Ki 0.0033Displacement of [3H]spiperone from dopamine D2 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometry [AID492642, Type: Literature]D(2) dopamine receptor [gi:47117674]
View
29
[SID103307946]
Ki 0.004Binding affinity to human 5HT2A receptor [AID516805, Type: Literature]5-hydroxytryptamine receptor 2A [gi:543727]
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30
[SID103307946]
Ki 0.004Binding affinity to human 5HT2A receptor [AID516805, Type: Literature]5-hydroxytryptamine receptor 2A [gi:543727]
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31
[SID103307946]
Ki 0.004Binding affinity to human 5HT2A receptor [AID516805, Type: Literature]5-hydroxytryptamine receptor 2A [gi:543727]
View
32
[SID103307946]
Ki 0.004Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cells [AID516804, Type: Literature]D(2) dopamine receptor [gi:118206]
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33
[SID103307946]
Ki 0.004Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cells [AID516804, Type: Literature]D(2) dopamine receptor [gi:118206]
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34
[SID103307946]
Ki 0.004Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cells [AID516804, Type: Literature]D(2) dopamine receptor [gi:118206]
View
35
[SID103307946]
Ki 0.004Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cells [AID516804, Type: Literature]D(2) dopamine receptor [gi:118206]
View
36
[SID103307946]
Ki 0.004Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cells [AID516804, Type: Literature]D(2) dopamine receptor [gi:118206]
View
37
[SID103307946]
Ki 0.0056Displacement of [3H]8OH-DPAT from 5HT1A receptor in rat CRL:CD(SD)BR-COBS hippocampus by scintillation spectrometry [AID492641, Type: Literature]5-hydroxytryptamine receptor 1A [gi:112812]
View
38
[SID103307946]
Ki 0.0056Displacement of [3H]8OH-DPAT from 5HT1A receptor in rat CRL:CD(SD)BR-COBS hippocampus by scintillation spectrometry [AID492641, Type: Literature]5-hydroxytryptamine receptor 1A [gi:112812]
View
39
[SID103307946]
Ki 0.0056Displacement of [3H]8OH-DPAT from 5HT1A receptor in CRL:CD(SD)BR-COBS rat hippocampus by scintillation spectrometry [AID410334, Type: Literature]5-hydroxytryptamine receptor 1A [gi:112812]
View
40
[SID103307946]
Ki 0.0056Displacement of [3H]8OH-DPAT from 5HT1A receptor in CRL:CD(SD)BR-COBS rat hippocampus by scintillation spectrometry [AID410334, Type: Literature]5-hydroxytryptamine receptor 1A [gi:112812]
View
41
[SID103307946]
Ki 0.0068Displacement of [125I]ABN from human recombinant D3 receptor expressed in HEK cells after 60 mins by gamma counter [AID610679, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
42
[SID103307946]
Ki 0.0068Displacement of [125I]ABN from human recombinant D3 receptor expressed in HEK cells after 60 mins by gamma counter [AID610679, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
43
[SID103307946]
Ki 0.0068Displacement of [125I]ABN from human recombinant D3 receptor expressed in HEK cells after 60 mins by gamma counter [AID610679, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
44
[SID103307946]
Ki 0.0068Displacement of [125I]ABN from human recombinant D3 receptor expressed in HEK cells after 60 mins by gamma counter [AID610679, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
45
[SID103307946]
Ki 0.007Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cells [AID516806, Type: Literature]5-hydroxytryptamine receptor 1A [gi:231454]
View
46
[SID103307946]
Ki 0.007Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cells [AID516806, Type: Literature]5-hydroxytryptamine receptor 1A [gi:231454]
View
47
[SID103307946]
Ki 0.007Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cells [AID516806, Type: Literature]5-hydroxytryptamine receptor 1A [gi:231454]
View
48
[SID103307946]
Ki 0.007Displacement of [3H]ketanserin from 5HT2A receptor in Wistar rat cortex homogenate [AID457689, Type: Literature]5-hydroxytryptamine receptor 2A [gi:112808]
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49
[SID103307946]
Ki 0.007Displacement of [3H]ketanserin from 5HT2A receptor in Wistar rat cortex homogenate [AID457689, Type: Literature]5-hydroxytryptamine receptor 2A [gi:112808]
View
50
[SID103307946]
Ki 0.0087Displacement of [3H]ketanserin from 5HT2A receptor in CRL:CD(SD)BR-COBS rat cortex by scintillation spectrometry [AID492640, Type: Literature]5-hydroxytryptamine receptor 2A [gi:112808]
View