mirfentanil (CID 60698) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Inactive(1)
 
 
Unspecified(8)
 
 
BioAssay Types:
Literature(10)
 
 
 
 
BioActivity Types:
Ki(1)
 
 
SAR
Target summary
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 11    Data Row: 11   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103410955]
Ki 0.0075Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane. [AID151900, Type: Literature]
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2
[SID85211959]
 Ligands of peptide (Class A) GPCRs [AID2063, Type: other]
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3
[SID103410955]
 Analgesic activity by mouse hot plate assay at 5.0 [AID133434, Type: Literature]
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4
[SID103410955]
 Ability of compound for reversal of morphine and analgesia was determined. [AID137455, Type: Literature]
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5
[SID103410955]
 Percentage of respirations per minute after treatment with morphine when compared to control in rabbit [AID165439, Type: Literature]
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6
[SID103410955]
 Maximum pharmacological effect of compound at 0.8 cumulative dose was determined by rabbit tooth pulp assay. [AID167147, Type: Literature]
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7
[SID103410955]
 Analgesic activity by rat hot plate assay [AID177773, Type: Literature]
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8
[SID103410955]
 Analgesic activity by rat tail flick assay [AID177775, Type: Literature]
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9
[SID103410955]
 Percentage analgesia of determined by mouse hot plate assay (5 mg/kg) [AID129029, Type: Literature]
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10
[SID103410955]
 Percentage analgesia determined by mouse hot plate assay (1 mg/kg) [AID129027, Type: Literature]
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11
[SID103410955]
 Percentage analgesia after treatment with compound or morphine in rabbit [AID165435, Type: Literature]
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