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BioActivity Data for Compound Tyrosine (CID 6057)

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BioActivity Outcomes:
Active(55)
 
 
Inactive(222)
 
 
Inconclusive(5)
 
 
Unspecified(23)
 
 
Top Targets:
alpha CA I II..(14)
 
 
 
alpha CA(11)
 
 
 
NR LBD PPAR(8)
 
 
 
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
BioAssay Types:
Literature(145)
 
 
 
 
 
Confirmatory(127)
 
 
 
Summary(24)
 
 
Screening(7)
 
 
BioActivity Types:
Potency(139)
 
 
 
AC50(3)
 
 
Ki(3)
 
 
 
Kd(2)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 236    Data Row: 305   Total Pages: 16   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46394400]
Kd 11.6Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of A Deletion Mutant Of A Tyrosyl-TRNA Synthetase Complexed With Tyrosine [gi:231099]
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2
[SID46394400]
Kd 11.6Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of A Deletion Mutant Of A Tyrosyl-TRNA Synthetase Complexed With Tyrosine [gi:231099]
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3
[SID46394031]
Ki 50Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Tyr-Bound T-State Of Yeast Chorismate Mutase [gi:313507253]
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4
[SID46394031]
Ki 50Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Tyr-Bound T-State Of Yeast Chorismate Mutase [gi:313507253]
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5
[SID103241488]
Activation of Candida glabrata recombinant carbonic anhydrase by stopped flow CO2 hydration method [AID464322, Type: Literature]Similar to sp|P53615 Saccharomyces cerevisiae YNL036w NCE3 [gi:74610182]
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6
[SID103241488]
Activation of Candida albicans beta-carbonic anhydrase Nce103 by stopped flow CO2 hydration assay [AID458784, Type: Literature]Carbonic anhydrase [gi:74656605]
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7
[SID103241488]
Activation of human recombinant CA9 catalytic domain by stopped-flow CO2 hydration method [AID318345, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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8
[SID103241488]
Activation of human recombinant CA6 by stopped flow CO2 hydrase method [AID307898, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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9
[SID103241488]
Activation of human full length CA6 by stopped flow CO2 hydration assay [AID462831, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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10
[SID46394031]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Tyr-Bound T-State Of Yeast Chorismate Mutase [gi:157881611]
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11
[SID103241488]
Activation of human recombinant CA7 by CO2 hydrase assay [AID291065, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
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12
[SID103241488]
Activation of human recombinant CA1 by CO2 hydrase assay [AID291061, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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13
[SID103241488]
Activation of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydrase method [AID305774, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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14
[SID103241488]
Activation of human recombinant CA1 by stopped flow CO2 hydrase method [AID307896, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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15
[SID103241488]
Activation of human recombinant CA1 by stopped-flow CO2 hydration method [AID318343, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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16
[SID103241488]
Activation of human recombinant CA1 at 10 uM by stopped-flow CO2 hydration method [AID365827, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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17
[SID103241488]
Activation of human recombinant carbonic anhydrase 5A by stopped-flow CO2 hydrase method [AID305776, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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18
[SID103241488]
Activation of human recombinant CA1 by stopped-flow CO2 hydrase assay [AID409984, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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19
[SID103241488]
Activation of human recombinant CA1 by stopped flow CO2 hydration assay [AID462829, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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20
[SID103241488]
Activity of human recombinant CA1 cytosolic isoform after 15 mins by phenol red staining based stopped flow CO2 hydration assay [AID691713, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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