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BioActivity Data for Compound Tyrosine (CID 6057)

BioActivity Outcomes:
Active(55)
 
 
Inactive(244)
 
 
Inconclusive(5)
 
 
Unspecified(23)
 
 
Top Targets:
alpha CA I II..(14)
 
 
 
alpha CA(11)
 
 
 
NR LBD PPAR(8)
 
 
 
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
BioAssay Types:
Literature(145)
 
 
 
 
 
Confirmatory(138)
 
 
 
Summary(27)
 
 
Screening(15)
 
 
BioAssay Categories:
In vitro(8)
 
 
Biochemical(59)
 
 
 
 
Toxicity(6)
 
 
ADME(3)
 
 
Cell-based(14)
 
 
 
BioActivity Types:
Potency(150)
 
 
 
AC50(6)
 
 
Ki(3)
 
 
 
Kd(2)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 258    Data Row: 327   Total Pages: 17   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46394400]
Kd 11.6Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of A Deletion Mutant Of A Tyrosyl-TRNA Synthetase Complexed With Tyrosine [gi:231099]
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2
[SID46394400]
Kd 11.6Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of A Deletion Mutant Of A Tyrosyl-TRNA Synthetase Complexed With Tyrosine [gi:231099]
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3
[SID46394031]
Ki 50Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Tyr-Bound T-State Of Yeast Chorismate Mutase [gi:313507253]
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4
[SID46394031]
Ki 50Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Tyr-Bound T-State Of Yeast Chorismate Mutase [gi:313507253]
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5
[SID46394031]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Tyr-Bound T-State Of Yeast Chorismate Mutase [gi:157881611]
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6
[SID103241488]
Activation of human recombinant CA3 at 10 uM by stopped-flow CO2 hydration method [AID365829, Type: Literature]Carbonic anhydrase 3 [gi:134047703]
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7
[SID103241488]
Activation of human recombinant CA3 by stopped-flow CO2 hydrase assay [AID409993, Type: Literature]Carbonic anhydrase 3 [gi:134047703]
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8
[SID103241488]
Activation of human recombinant CA7 by CO2 hydrase assay [AID291065, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
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9
[SID103241488]
Activation of human recombinant CA6 by stopped flow CO2 hydrase method [AID307898, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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10
[SID103241488]
Activation of human full length CA6 by stopped flow CO2 hydration assay [AID462831, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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11
[SID46394400]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Crystal Structure Of A Deletion Mutant Of A Tyrosyl-TRNA Synthetase Complexed With Tyrosine [gi:231099]
View
12
[SID103241488]
Activation of human recombinant carbonic anhydrase 5A by stopped-flow CO2 hydrase method [AID305776, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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13
[SID103241488]
Activation of human recombinant CA2 by stopped-flow CO2 hydrase assay [AID409986, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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14
[SID103241488]
Activation of human recombinant CA2by stopped flow CO2 hydration assay [AID462830, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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15
[SID103241488]
Activation of human recombinant carbonic anhydrase isoenzyme 2 by stopped flow CO2 hydration method [AID464319, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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16
[SID103241488]
Activation of human recombinant CA2 by stopped-flow CO2 hydrase method [AID414329, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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17
[SID103241488]
Activity of human recombinant CA2 cytosolic isoform after 15 mins by phenol red staining based stopped flow CO2 hydration assay [AID691714, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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18
[SID103241488]
Activation of human recombinant CA2 by stopped flow CO2 hydrase method [AID725229, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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19
[SID103241488]
Activation of human recombinant truncated CA4 at 10 uM by stopped-flow CO2 hydration method [AID365830, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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20
[SID103241488]
Activation of human recombinant carbonic anhydrase 4 lacking 20 amino terminal residues by stopped-flow CO2 hydrase method [AID375786, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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