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Tyrosine (CID 6057) - Compound BioActivity Data
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BioActivity Outcomes:
Active(51)
 
 
Inactive(217)
 
 
Inconclusive(6)
 
 
Unspecified(20)
 
 
Top Targets:
alpha CA I II..(24)
 
 
 
NR LBD PPAR(8)
 
 
 
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
NR LBD TR(5)
 
 
BioAssay Types:
Literature(132)
 
 
 
 
 
Confirmatory(123)
 
 
 
Summary(24)
 
 
Screening(7)
 
 
BioActivity Types:
Potency(138)
 
 
 
Ki(1)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 227    Data Row: 294   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID48416689]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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2
[SID103241488]
Activation of Methanobacterium thermoautotrophicum beta-class CA by stopped-flow CO2 hydrase assay [AID409988, Type: Literature]
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3
[SID103241488]
Activation of Methanosarcina thermophila Zinc(2)-derived gamma-class CA by stopped-flow CO2 hydrase assay [AID409990, Type: Literature]
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4
[SID103241488]
Activation of Methanothermobacter thermautotrophicus recombinant Cab by stopped-flow CO2 hydrase method [AID414330, Type: Literature]
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5
[SID103241488]
Antiinflammatory activity against trinitrobenzenesulfonic acid-induced colitis in Wistar rat assessed as decrease in appearance of mucosal abscess at 100 mg/kg administered rectally measured 24 hrs after last dose on day 11 by haematoxylin/eosin staining [AID436243, Type: Literature]
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6
[SID103241488]
Antiinflammatory activity against trinitrobenzenesulfonic acid-induced colitis in Wistar rat assessed as decrease in inflammatory cell infiltration at 100 mg/kg administered rectally measured 24 hrs after last dose on day 11 by haematoxylin/eosin staining in presence of sulfasalazine [AID436244, Type: Literature]
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7
[SID103241488]
Activation of Cryptococcus neoformans beta-carbonic anhydrase Can2 by stopped flow CO2 hydration assay [AID458787, Type: Literature]
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8
[SID103241488]
Activation of Stylophora pistillata carbonic anhydrase STPCA by stopped flow CO2 hydration assay [AID462832, Type: Literature]
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9
[SID103241488]
Induction of nitrogen-starved wild type sigma1278b yeast Gap1-mediated trehalose activation at 10 mM [AID500825, Type: Literature]
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10
[SID103241488]
Activation of archaea Methanobacterium thermoautotrophicum recombinant carbonic anhydrase by stopped flow CO2 hydration method [AID464320, Type: Literature]
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11
[SID103241488]
Activity of Sulfurihydrogenibium yellowstonense YO3AOP1 recombinant CA expressed in Escherichia coli BL21(DE3) after 15 mins by phenol red staining based stopped flow CO2 hydration assay [AID691715, Type: Literature]
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12
[SID103241488]
Activation of Sulfurihydrogenibium azorense recombinant alpha carbonic anhydrase by stopped flow CO2 hydrase method [AID725226, Type: Literature]
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13
[SID103241488]
Activation of Sulfurihydrogenibium yellowstonense recombinant CA by stopped flow CO2 hydrase method [AID725227, Type: Literature]
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14
[SID103241488]
Activity of human recombinant CA1 cytosolic isoform after 15 mins by phenol red staining based stopped flow CO2 hydration assay [AID691713, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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15
[SID103241488]
Activation of human recombinant CA1 by stopped flow CO2 hydrase method [AID725228, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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16
[SID103241488]
Activation of human recombinant CA1 by stopped flow CO2 hydration assay [AID462829, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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17
[SID103241488]
Activation of human recombinant CA1 by CO2 hydrase assay [AID291061, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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18
[SID103241488]
Activation of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydrase method [AID305774, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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19
[SID103241488]
Activation of human recombinant CA1 by stopped flow CO2 hydrase method [AID307896, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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20
[SID103241488]
Activation of human recombinant CA1 by stopped-flow CO2 hydration method [AID318343, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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21
[SID103241488]
Activation of human recombinant CA1 at 10 uM by stopped-flow CO2 hydration method [AID365827, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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22
[SID103241488]
Activation of human recombinant CA2 by stopped-flow CO2 hydrase assay [AID409986, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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23
[SID103241488]
Activation of human recombinant CA2 at 10 uM by stopped-flow CO2 hydration method [AID365828, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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24
[SID103241488]
Activation of human recombinant CA2 by stopped-flow CO2 hydration method [AID318344, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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25
[SID103241488]
Activation of human recombinant CA2 by stopped flow CO2 hydrase method [AID307897, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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26
[SID103241488]
Activation of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydrase method [AID305775, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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27
[SID103241488]
Activation of human recombinant CA2 by CO2 hydrase assay [AID291063, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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28
[SID103241488]
Activation of human recombinant CA2by stopped flow CO2 hydration assay [AID462830, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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29
[SID103241488]
Activation of human recombinant carbonic anhydrase isoenzyme 2 by stopped flow CO2 hydration method [AID464319, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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30
[SID103241488]
Activation of human recombinant CA2 by stopped flow CO2 hydrase method [AID725229, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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31
[SID103241488]
Activity of human recombinant CA2 cytosolic isoform after 15 mins by phenol red staining based stopped flow CO2 hydration assay [AID691714, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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32
[SID103241488]
Activation of human recombinant CA2 by stopped-flow CO2 hydrase method [AID414329, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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33
[SID103241488]
Activation of human recombinant truncated CA4 at 10 uM by stopped-flow CO2 hydration method [AID365830, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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34
[SID103241488]
Activation of human recombinant carbonic anhydrase 4 lacking 20 aminoterminal residues by stopped-flow CO2 hydrase method [AID375786, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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35
[SID103241488]
Antiinflammatory activity against trinitrobenzenesulfonic acid-induced colitis in Wistar rat at 100 mg/kg, administered rectally in presence of 5-aminosalicylic acid [AID436238, Type: Literature]
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36
[SID103241488]
Activation of human recombinant CA1 by stopped-flow CO2 hydrase assay [AID409984, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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37
[SID103241488]
Activation of human recombinant carbonic anhydrase 5A by stopped-flow CO2 hydrase method [AID305776, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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38
[SID46394400]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Crystal Structure Of A Deletion Mutant Of A Tyrosyl-TRNA Synthetase Complexed With Tyrosine [gi:231099]
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39
[SID103241488]
Activation of human recombinant CA7 by CO2 hydrase assay [AID291065, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
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40
[SID103241488]
Activation of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method [AID318346, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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41
[SID103241488]
Activation of of human recombinant CA14 by CO2 hydrase assay [AID291067, Type: Literature]Carbonic anhydrase 14 [gi:8928036]
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42
[SID103241488]
Activation of human recombinant carbonic anhydrase 5B by stopped-flow CO2 hydrase method [AID305777, Type: Literature]Carbonic anhydrase 5B, mitochondrial [gi:8928041]
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43
[SID103241488]
Activation of membrane associated mouse recombinant carbonic anhydrase 15 isoform by stopped-flow CO2 hydrase method [AID375787, Type: Literature]Carbonic anhydrase 15 [gi:30580362]
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44
[SID103241488]
Activation of Candida glabrata recombinant carbonic anhydrase by stopped flow CO2 hydration method [AID464322, Type: Literature]Similar to sp|P53615 Saccharomyces cerevisiae YNL036w NCE3 [gi:74610182]
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45
[SID103241488]
Activation of Candida albicans beta-carbonic anhydrase Nce103 by stopped flow CO2 hydration assay [AID458784, Type: Literature]Carbonic anhydrase [gi:74656605]
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46
[SID103241488]
Activation of human recombinant CA9 catalytic domain by stopped-flow CO2 hydration method [AID318345, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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47
[SID103241488]
Activation of human recombinant CA6 by stopped flow CO2 hydrase method [AID307898, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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48
[SID103241488]
Activation of human full length CA6 by stopped flow CO2 hydration assay [AID462831, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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49
[SID46394031]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Tyr-Bound T-State Of Yeast Chorismate Mutase [gi:157881611]
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50
[SID103241488]
Activation of human recombinant CA3 by stopped-flow CO2 hydrase assay [AID409993, Type: Literature]Carbonic anhydrase 3 [gi:134047703]
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