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Uridine Monophosphate (CID 6030) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(31)
 
 
Inconclusive(2)
 
 
Unspecified(8)
 
 
Top Targets:
ADK(4)
 
 
OMP decarboxy..(4)
 
 
 
PRTases typeI(3)
 
 
PLDc mTdp1 2(3)
 
 
 
Tubulin-bindi..(2)
 
 
BioAssay Types:
Confirmatory(33)
 
 
 
 
Literature(15)
 
 
 
 
BioActivity Types:
Potency(30)
 
 
 
 
Ki(6)
 
 
 
Kd(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 44    Data Row: 48   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46393604]
Kd 30Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Pyrr, The Regulator Of The Pyrimidine Biosynthetic Operon In Bacillus Caldolyticus, Nucleotide-Bound Form [gi:61680477]
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2
[SID46393604]
Kd 30Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Pyrr, The Regulator Of The Pyrimidine Biosynthetic Operon In Bacillus Caldolyticus, Nucleotide-Bound Form [gi:61680477]
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3
[SID26756680]
Potency 37.6858Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS [AID504845, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301163]
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4
[SID46392447]
Ki 200Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Orotidine Monophosphate Decarboxylase Complexed With Product Ump [gi:22219261]
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5
[SID46392447]
Ki 200Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Orotidine Monophosphate Decarboxylase Complexed With Product Ump [gi:22219261]
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6
[SID46392447]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Crystal Structure Of Orotidine Monophosphate Decarboxylase Complexed With Product Ump [gi:22219261]
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7
[SID46393604]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain B, Pyrr, The Regulator Of The Pyrimidine Biosynthetic Operon In Bacillus Caldolyticus, Nucleotide-Bound Form [gi:61680477]
View
8
[SID103497422]
Km 151Activity of cloned UMP-CMP kinase in human HuH7 cells assessed as formation of uridine diphosphate by spectrophotometry [AID431259, Type: Literature]UMP-CMP kinase [gi:12644008]
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9
[SID103497422]
Km 151Activity of human YMPK expressed in Huh7 cells assessed as phosphorylation by coupled enzyme assay [AID278934, Type: Literature]UMP-CMP kinase [gi:12644008]
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10
[SID103497422]
Ki 210Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetry [AID707245, Type: Literature]Orotidine 5' monophosphate decarboxylase [gi:74819331]
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11
[SID103497422]
Ki 220Inhibition of human ODCase by isothermal titration calorimetry [AID707246, Type: Literature]Uridine 5'-monophosphate synthase [gi:131708]
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12
[SID103497422]
Ki 330Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetry [AID707247, Type: Literature]
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13
[SID103497422]
Ki 4000Competitive inhibition of bovine pancreatic RNase A type 12-A by Dixon plot analysis [AID718079, Type: Literature]
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14
[SID103497422]
Ratio of Kcat to Km for YMPK activity expressed in Huh7 cells [AID278935, Type: Literature]UMP-CMP kinase [gi:12644008]
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15
[SID103497422]
Ratio of Kcat to Km for cloned UMP-CMP kinase in human HuH7 cells assessed as formation of uridine diphosphate by spectrophotometry [AID431261, Type: Literature]UMP-CMP kinase [gi:12644008]
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16
[SID26756680]
Potency qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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17
[SID26756680]
Potency qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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18
[SID26756680]
qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore) [AID880, Type: confirmatory]guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 [Homo sapiens] [gi:33946324]
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19
[SID26756680]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase 1 [gi:44888968]
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20
[SID26756680]
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP) [AID1471, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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