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DSSTox_CID_267 (CID 60196414) - Compound BioActivity Data
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BioActivity Outcomes:
Active(23)
 
 
Inactive(19)
 
 
Inconclusive(44)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD GR(4)
 
 
BioAssay Types:
Confirmatory(62)
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(80)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 86    Data Row: 86   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210903]
Ratio Potency (uM) 9.32377qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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2
[SID144210903]
Potency-Replicate_1 13.6854qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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3
[SID144210903]
Potency-Replicate_1 17.3739qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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4
[SID144210903]
Ratio Potency (uM) 21.6899qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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5
[SID144210903]
Potency-Replicate_1 21.6899qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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6
[SID144210903]
Potency-Replicate_1 24.3365qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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7
[SID144210903]
Potency-Replicate_1 24.3365qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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8
[SID144210903]
Potency-Replicate_1 24.3365qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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9
[SID144210903]
Potency-Replicate_1 24.5412qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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10
[SID144210903]
Potency-Replicate_1 24.5412qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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11
[SID144210903]
Potency-Replicate_1 30.6379qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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12
[SID144210903]
Potency-Replicate_1 38.8952qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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13
[SID144210903]
Potency-Replicate_1 43.6412qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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14
[SID144210903]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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15
[SID144210903]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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16
[SID144210903]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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17
[SID144210903]
Ratio Potency (uM) 54.941qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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18
[SID144210903]
Potency-Replicate_1 54.941qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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19
[SID144210903]
Potency-Replicate_1 61.1306qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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20
[SID144210903]
Potency-Replicate_1 61.1306qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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