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AGN-PC-0DB7S3 (CID 60196397) - Compound BioActivity Data
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BioActivity Outcomes:
Active(25)
 
 
Inactive(24)
 
 
Inconclusive(37)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD GR(4)
 
 
BioAssay Types:
Confirmatory(62)
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(80)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 86    Data Row: 86   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209910]
Potency-Replicate_1 0.2182qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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2
[SID144209910]
Potency-Replicate_1 0.2182qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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3
[SID144209910]
Potency-Replicate_1 0.2771qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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4
[SID144209910]
Potency-Replicate_1 0.3881qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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5
[SID144209910]
Potency-Replicate_1 0.6901qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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6
[SID144209910]
Potency-Replicate_1 0.9833qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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7
[SID144209910]
Ratio Potency (uM) 1.0129qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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8
[SID144209910]
Potency-Replicate_1 2.7473qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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9
[SID144209910]
Potency-Replicate_1 3.4586qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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10
[SID144209910]
Potency-Replicate_1 4.3541qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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11
[SID144209910]
Potency-Replicate_1 4.3541qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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12
[SID144209910]
Potency-Replicate_1 4.3541qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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13
[SID144209910]
Potency-Replicate_1 5.4815qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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14
[SID144209910]
Potency-Replicate_1 8.7641qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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15
[SID144209910]
Potency-Replicate_1 11.0333qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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16
[SID144209910]
Potency-Replicate_1 15.449qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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17
[SID144209910]
Potency-Replicate_1 17.4866qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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18
[SID144209910]
Potency-Replicate_1 19.4492qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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19
[SID144209910]
Potency-Replicate_1 22.0143qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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20
[SID144209910]
Ratio Potency (uM) 22.8756qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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