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BioActivity Data for Compound DSSTox_CID_26448 (CID 60196288)

BioActivity Outcomes:
Active(11)
 
 
Inactive(50)
 
 
Inconclusive(19)
 
 
Top Targets:
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
NR LBD GR(4)
 
 
 
NR LBD TR(3)
 
 
 
 
7tm 4(2)
 
 
BioAssay Types:
Confirmatory(61)
 
 
 
 
Summary(17)
 
 
 
 
Screening(2)
 
 
BioAssay Categories:
Toxicity(6)
 
 
 
BioActivity Types:
Potency(70)
 
 
 
 
AC50(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 80    Data Row: 80   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144205748]
Potency-Replicate_1 0.0944qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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2
[SID251919808]
Potency-Replicate_1 0.3661qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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3
[SID144205748]
Potency-Replicate_1 0.5308qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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4
[SID144205748]
Ratio Potency (uM) 1.15344qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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5
[SID144205748]
Potency-Replicate_1 1.6785qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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6
[SID144205748]
Potency-Replicate_1 1.693qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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7
[SID144205748]
Potency 1.8837qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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8
[SID144205748]
Potency 2.6609qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID144205748]
TR Potency (uM) 26.6032qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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10
[SID144205748]
qHTS assay to identify aromatase inhibitors: Summary [AID743139, Type: summary]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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11
[SID144205748]
qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720725, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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12
[SID144205748]
AC50 (uM) 1qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen1 green channel [AID1117302, Type: confirmatory]
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13
[SID144205748]
Ac50 1qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, green channel [AID1117315, Type: confirmatory]
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14
[SID144205748]
Potency-Replicate_1 3.3491qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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15
[SID144205748]
Ac50 14.1254qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, ratio channel [AID1117318, Type: confirmatory]
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16
[SID144205748]
AC50 (uM) 14.13qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 1 ratio channel [AID1117303, Type: confirmatory]
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17
[SID144205748]
Ac50 17.7828qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, blue channel [AID1117311, Type: confirmatory]
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18
[SID144205748]
AC50 (uM) 17.7828qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 1 blue channel [AID1117301, Type: confirmatory]
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19
[SID144205748]
Potency qHTS Assay for Identifying Gametocytocidal Compounds [AID743244, Type: confirmatory]
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20
[SID144205748]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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