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BRD-K43067295-001-01-5 (CID 60192602) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(24)
 
 
Inconclusive(1)
 
 
Top Targets:
ABCC CFTR1(1)
 
 
CASc(1)
 
 
CLECT selecti..(1)
 
 
M1 APN 2(1)
 
 
P5 C(1)
 
 
BioAssay Types:
Screening(22)
 
 
 
 
Confirmatory(5)
 
 
 
BioActivity Types:
AC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 27    Data Row: 27   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144198641]
AbsAC40_uM 6.06MLPCN PGC1a Modulators Measured in Cell-Based System Using Plate Reader - 2139-01_Activator_Dose_CherryPick_Activity_Set6 [AID720513, Type: confirmatory]
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2
[SID144198641]
MLPCN PGC1a Modulators Measured in Cell-Based System Using Plate Reader - 2139-01_Activator_SinglePoint_HTS_Activity [AID651723, Type: screening]
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3
[SID144198641]
MLPCN SirT-5 Measured in Biochemical System Using Imaging - 7044-01_Inhibitor_SinglePoint_HTS_Activity_Set5 [AID652115, Type: screening]NAD-dependent protein deacylase sirtuin-5, mitochondrial [gi:38258652]
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4
[SID144198641]
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity [AID652154, Type: screening]PAX8 [Homo sapiens] [gi:998701]
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5
[SID144198641]
C. difficile toxins: HTS for inhibitors of TcdB glycohydrolase activity Measured in Biochemical System Using Plate Reader - 7074-01_Inhibitor_SinglePoint_HTS_Activity [AID652162, Type: screening]toxin B [Clostridium difficile 630] [gi:126698238]
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6
[SID144198641]
S100A4: HTS Measured in Biochemical System Using Plate Reader - 7045-01_Inhibitor_SinglePoint_HTS_Activity [AID652163, Type: screening]S100A4 [Homo sapiens] [gi:47496637]
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7
[SID144198641]
MLPCN ERAP1 Measured in Biochemical System Using Plate Reader - 7016-01_Inhibitor_SinglePoint_HTS_Activity [AID652197, Type: screening]ERAP1 protein [Homo sapiens] [gi:21315078]
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8
[SID144198641]
Identification of agents that induce E-selectin on human endothelial cells Measured in Cell-Based System Using Imaging - 2152-01_Activator_SinglePoint_HTS_Activity [AID686992, Type: screening]E-selectin precursor [Homo sapiens] [gi:187960042]
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9
[SID144198641]
VEID(2) R110 Enzymatic Primary HTS to identify Inhibitors of Caspase 6 Measured in Biochemical System Using Plate Reader - 7052-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID686996, Type: screening]Caspase 6, apoptosis-related cysteine peptidase [Homo sapiens] [gi:13325293]
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10
[SID144198641]
Identification of Small Molecule Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Delta508 Mutation Function in Human Bronchial Epithelial Cells. Measured in Cell-Based System Using Plate Reader - 7017-01_Other_SinglePoint_HTS_Activity [AID720511, Type: screening]cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7 [Homo sapiens] [gi:89348172]
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11
[SID144198641]
AC50_uM MLPCN PGC1a Modulators Measured in Cell-Based System Using Plate Reader - 2139-01_Inhibitor_Dose_CherryPick_Activity [AID720514, Type: confirmatory]
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12
[SID144198641]
HTS to Identify Inhibitors of Demethylase GASC-1 Measured in Biochemical System Using Plate Reader - 2043-05_Inhibitor_SinglePoint_HTS_Activity [AID720574, Type: screening]Jumonji domain containing 2C [Homo sapiens] [gi:219520678]
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13
[SID144198641]
7011-01_Antagonist_SinglePoint_HTS_Activity [AID720647, Type: screening]
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14
[SID144198641]
HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate Reader - 7056-01_Inhibitor_SinglePoint_HTS_Activity [AID720706, Type: screening]
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15
[SID144198641]
High Content Cell-Based Imaging Primary HTS to Identify Small Molecules Involved in X-Chromosome Reactivation and Reprogramming Measured in Cell-Based System Using Imaging - 7015-01_Activator_SinglePoint_HTS_Activity_Set2 [AID743238, Type: screening]
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16
[SID144198641]
Inhibition of Alexa 488-Fibronectin deposition #on AH1F cell monolayers Measured in Cell-Based System Using Plate Reader - 7059-01_Inhibitor_SinglePoint_HTS_Activity [AID743247, Type: screening]
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17
[SID144198641]
Luminescent GLuc Reporter Gene Assay Primary HTS to Identify Small Molecule Activator of Glucose Dependent Insulin Secretion Measured in Cell-Based System Using Plate Reader - 7055-01_Activator_SinglePoint_HTS_Activity [AID743287, Type: screening]
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18
[SID144198641]
AC50_uM PGC-1a: Effect of activators of PGC-1a acetylation on target gene expression G6PC in hepatocyte, using qPCR Measured in Cell-Based System Using RT-PCR - 2139-05_Activator_Dose_CherryPick_Activity [AID743463, Type: confirmatory]
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19
[SID144198641]
AC50_uM PGC-1a: Effect of activators of PGC-1a acetylation of target gene expression PCK1 in hepatocytes, using qPCR Measured in Cell-Based System Using RT-PCR - 2139-04_Activator_Dose_CherryPick_Activity [AID743465, Type: confirmatory]
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20
[SID144198641]
AC50_uM PGC-1a: Effect of activators of PGC-1a acetylation on target gene expression PGC-1a in hepatocyte, using qPCR Measured in Cell-Based System Using RT-PCR - 2139-03_Activator_Dose_CherryPick_Activity [AID743467, Type: confirmatory]
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