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BioActivity Data for Compound CHEMBL2356728 (CID 60190920)

BioActivity Outcomes:
Active(11)
 
 
Inactive(28)
 
 
Inconclusive(4)
 
 
Top Targets:
PAX(8)
 
 
 
 
ABCC CFTR1(1)
 
 
CASc(1)
 
 
CLECT selecti..(1)
 
 
M1 APN 2(1)
 
 
BioAssay Types:
Screening(23)
 
 
 
Confirmatory(20)
 
 
 
 
BioAssay Categories:
Organism-base..(3)
 
 
Biochemical(9)
 
 
Toxicity(13)
 
 
 
 
Cell-based(32)
 
 
 
 
BioActivity Types:
AC50(20)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 43    Data Row: 43   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144196939]
AC50_uM 0.00447SA7-Pax8: cytotoxicity COV434 Measured in Cell-Based System Using Plate Reader - 7054-09_Inhibitor_Dose_DryPowder_Activity [AID743145, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
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2
[SID144196939]
AC50_uM 3.15HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_Dose_CherryPick_Activity [AID687027, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
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3
[SID144196939]
AC50_uM 5.77PAX8: PAX8-dependent cytoxicity Measured in Cell-Based System Using Plate Reader - 7054-06_Inhibitor_Dose_DryPowder_Activity [AID743049, Type: confirmatory]
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4
[SID144196939]
AC50_uM 17.03Cell fusion assay for clade C HIV-1ZM109 Env Measured in Cell-Based System Using Plate Reader - 7013-05_Inhibitor_Dose_CherryPick_Activity [AID652058, Type: confirmatory]
View
5
[SID144196939]
AC50_uM 17.78HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_Dose_CherryPick_Activity [AID652057, Type: confirmatory]
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6
[SID144196939]
AC50_uM 20.02HIV-1 Cell Fusion assay for clade B Env AD8 Measured in Cell-Based System Using Plate Reader - 7013-04_Inhibitor_Dose_CherryPick_Activity [AID652062, Type: confirmatory]
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7
[SID144196939]
AC50_uM 30.11SA2 PAX8:selectivity PAX5 Measured in Cell-Based System Using Plate Reader - 7054-03_Inhibitor_Dose_DryPowder_Activity [AID743047, Type: confirmatory]
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8
[SID144196939]
AC50_uM 30.84Pax8 Selectivity: PAx2 Measured in Cell-Based System Using Plate Reader - 7054-02_Inhibitor_Dose_DryPowder_Activity [AID743048, Type: confirmatory]
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9
[SID144196939]
AC50_uM 37.88SA11 PAX8: cytotoxicity OVCAR4 Measured in Cell-Based System Using Plate Reader - 7054-13_Inhibitor_Dose_DryPowder_Activity [AID743150, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
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10
[SID144196939]
HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
View
11
[SID144196939]
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity [AID652154, Type: screening]PAX8 [Homo sapiens] [gi:998701]
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12
[SID144196939]
AC50_uM SA5-Pax8: Cytotoxicity IOSE-T80 Measured in Cell-Based System Using Plate Reader - 7054-07_Inhibitor_Dose_CherryPick_Activity [AID687032, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
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13
[SID144196939]
AC50_uM PAX8: PAX8-dependent cytoxicity Measured in Cell-Based System Using Plate Reader - 7054-06_Inhibitor_Dose_CherryPick_Activity [AID687029, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
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14
[SID144196939]
Assay for stage-specific inhibitors of Vaccinia orthopox Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2142-01_Inhibitor_SinglePoint_HTS_Activity [AID1053133, Type: screening]
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15
[SID144196939]
AC50_uM SA8-Pax8: cytotoxicity OV-90 Measured in Cell-Based System Using Plate Reader - 7054-10_Inhibitor_Dose_DryPowder_Activity [AID743149, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
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16
[SID144196939]
Turbidometric Biochemical Primary HTS to identify inhibitors of ERp5 Measured in Biochemical System Using Plate Reader - 7002-01_Inhibitor_SinglePoint_HTS_Activity [AID651711, Type: screening]Protein disulfide-isomerase A6 [gi:2501205]
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17
[SID144196939]
VEID(2) R110 Enzymatic Primary HTS to identify Inhibitors of Caspase 6 Measured in Biochemical System Using Plate Reader - 7052-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID686996, Type: screening]Caspase 6, apoptosis-related cysteine peptidase [Homo sapiens] [gi:13325293]
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18
[SID144196939]
MLPCN ERAP1 Measured in Biochemical System Using Plate Reader - 7016-01_Inhibitor_SinglePoint_HTS_Activity [AID652197, Type: screening]ERAP1 protein [Homo sapiens] [gi:21315078]
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19
[SID144196939]
MLPCN SirT-5 Measured in Biochemical System Using Imaging - 7044-01_Inhibitor_SinglePoint_HTS_Activity_Set5 [AID652115, Type: screening]NAD-dependent protein deacylase sirtuin-5, mitochondrial [gi:38258652]
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20
[SID144196939]
S100A4: HTS Measured in Biochemical System Using Plate Reader - 7045-01_Inhibitor_SinglePoint_HTS_Activity [AID652163, Type: screening]S100A4, partial [Homo sapiens] [gi:47496637]
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