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BRD-K84673253-001-01-0 (CID 60188775) - Compound BioActivity Data
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BioActivity Outcomes:
Active(14)
 
 
Inactive(29)
 
 
Inconclusive(3)
 
 
Top Targets:
PAX(4)
 
 
 
 
rad52(1)
 
 
M1 APN 2(1)
 
 
S-100(1)
 
 
CLECT selecti..(1)
 
 
BioAssay Types:
Screening(23)
 
 
 
 
Confirmatory(23)
 
 
 
 
BioActivity Types:
AC50(19)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 46    Data Row: 46   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144194774]
AC50_uM 3.59LGR2:Counterscreen with MC4R Measured in Cell-Based System Using Plate Reader - 7011-02_Antagonist_Dose_CherryPick_Activity [AID743444, Type: confirmatory]MSH [Drosophila melanogaster] [gi:1098680]
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2
[SID144194774]
AC50_uM 4.17MLPCN PGC1a Modulators Measured in Cell-Based System Using Plate Reader - 2139-01_Inhibitor_Dose_CherryPick_Activity [AID720514, Type: confirmatory]
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3
[SID144194774]
AC50_uM 4.38HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_Dose_CherryPick_Activity [AID687027, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
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4
[SID144194774]
AC50_uM 8.21SA9-PAX8: cytotoxicity NIHOVCAR3 Measured in Cell-Based System Using Plate Reader - 7054-11_Inhibitor_Dose_DryPowder_Activity [AID743044, Type: confirmatory]
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5
[SID144194774]
AC50_uM 9.13Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition Measured in Cell-Based System Using Plate Reader - 7011-01_Antagonist_Dose_CherryPick_Activity_Set2 [AID743343, Type: confirmatory]
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6
[SID144194774]
AC50_uM 9.51HIV-1 Cell Fusion assay for clade B Env AD8 Measured in Cell-Based System Using Plate Reader - 7013-04_Inhibitor_Dose_CherryPick_Activity [AID652062, Type: confirmatory]
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7
[SID144194774]
AC50_uM 10.55SA13 PAX8: cytotoxicity OVCAR8 Measured in Cell-Based System Using Plate Reader - 7054-15_Inhibitor_Dose_DryPowder_Activity [AID743197, Type: confirmatory]
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8
[SID144194774]
AC50_uM 19.76PAX8: non-specific cytotoxicity Measured in Cell-Based System Using Plate Reader - 7054-05_Inhibitor_Dose_DryPowder_Activity [AID743021, Type: confirmatory]
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9
[SID144194774]
AC50_uM 21.83SA5-Pax8: Cytotoxicity IOSE-T80 Measured in Cell-Based System Using Plate Reader - 7054-07_Inhibitor_Dose_DryPowder_Activity [AID743045, Type: confirmatory]
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10
[SID144194774]
AC50_uM 32.21SA10 PAX8: cytotoxicity IGROV1 Measured in Cell-Based System Using Plate Reader - 7054-12_Inhibitor_Dose_DryPowder_Activity [AID743043, Type: confirmatory]
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11
[SID144194774]
HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
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12
[SID144194774]
7011-01_Antagonist_SinglePoint_HTS_Activity [AID720647, Type: screening]
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13
[SID144194774]
MLPCN PGC1a Modulators Measured in Cell-Based System Using Plate Reader - 2139-01_Inhibitor_SinglePoint_HTS_Activity [AID651687, Type: screening]
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14
[SID144194774]
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity [AID652154, Type: screening]PAX8 [Homo sapiens] [gi:998701]
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15
[SID144194774]
AC50_uM 52A549 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-06_Antagonist_Dose_CherryPick_Activity [AID743412, Type: confirmatory]
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16
[SID144194774]
AC50_uM 52HEK293 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-01_Antagonist_Dose_CherryPick_Activity [AID743446, Type: confirmatory]
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17
[SID144194774]
AbsAC35_uM PGC-1a: Gene expression assay to measure PGC-1a target levels in C2C12 myotubes using qPCR, COX5a Measured in Cell-Based System Using RT-PCR - 2139-07_Inhibitor_Dose_CherryPick_Activity [AID743461, Type: confirmatory]
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18
[SID144194774]
AbsAC40_uM PGC-1a; Gene expression assay to measure PGC-1a target levels in C2C12 myotubes using qPCR, COX8b Measured in Cell-Based System Using RT-PCR - 2139-08_Inhibitor_Dose_CherryPick_Activity [AID743464, Type: confirmatory]
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19
[SID144194774]
AbsAC35_uM PGC-1a: Gene expression assay to measure PGC-1a target levels in C2C12 myotubes, using qPCR, PDK4 Measured in Cell-Based System Using RT-PCR - 2139-06_Inhibitor_Dose_CherryPick_Activity [AID743468, Type: confirmatory]
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20
[SID144194774]
AC50_uM HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Antagonist_Dose_CherryPick_Activity [AID743416, Type: confirmatory]
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