Bookmark and Share
BRD-K65854902-001-01-4 (CID 60188423) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(5)
 
 
Inactive(27)
 
 
Inconclusive(1)
 
 
Top Targets:
PAX(4)
 
 
 
rad52(1)
 
 
M1 APN 2(1)
 
 
S-100(1)
 
 
CLECT selecti..(1)
 
 
BioAssay Types:
Screening(23)
 
 
 
 
Confirmatory(10)
 
 
 
BioActivity Types:
AC50(10)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 33    Data Row: 33   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144194411]
AC50_uM 9.89HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_Dose_CherryPick_Activity [AID687027, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
View
2
[SID144194411]
AC50_uM 43.72SA13 PAX8: cytotoxicity OVCAR8 Measured in Cell-Based System Using Plate Reader - 7054-15_Inhibitor_Dose_DryPowder_Activity [AID743197, Type: confirmatory]
View
3
[SID144194411]
AC50_uM 53.01SA10 PAX8: cytotoxicity IGROV1 Measured in Cell-Based System Using Plate Reader - 7054-12_Inhibitor_Dose_DryPowder_Activity [AID743043, Type: confirmatory]
View
4
[SID144194411]
Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based System Using Plate Reader - 7124-01_Inhibitor_SinglePoint_HTS_Activity [AID1053188, Type: screening]
View
5
[SID144194411]
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity [AID652154, Type: screening]PAX8 [Homo sapiens] [gi:998701]
View
6
[SID144194411]
HTS to identify Pax4 expression activator Measured in Cell-Based System Using RT-PCR - 7144-01_Activator_SinglePoint_HTS_Activity [AID1053180, Type: screening]
View
7
[SID144194411]
High Content Cell-Based Imaging Primary HTS to Identify Small Molecules Involved in X-Chromosome Reactivation and Reprogramming Measured in Cell-Based System Using Imaging - 7015-01_Activator_SinglePoint_HTS_Activity_Set2 [AID743238, Type: screening]
View
8
[SID144194411]
Inhibition of Alexa 488-Fibronectin deposition #on AH1F cell monolayers Measured in Cell-Based System Using Plate Reader - 7059-01_Inhibitor_SinglePoint_HTS_Activity [AID743247, Type: screening]
View
9
[SID144194411]
Luminescent GLuc Reporter Gene Assay Primary HTS to Identify Small Molecule Activator of Glucose Dependent Insulin Secretion Measured in Cell-Based System Using Plate Reader - 7055-01_Activator_SinglePoint_HTS_Activity [AID743287, Type: screening]
View
10
[SID144194411]
HTS for YAP1 pathway inhibitors in DLD1 colon cancer cell line measuring mRNA levels of CTGF Measured in Cell-Based System Using RT-PCR - 7098-01_Inhibitor_SinglePoint_HTS_Activity [AID743449, Type: screening]
View
11
[SID144194411]
AC50_uM SA9-PAX8: cytotoxicity NIHOVCAR3 Measured in Cell-Based System Using Plate Reader - 7054-11_Inhibitor_Dose_DryPowder_Activity [AID743044, Type: confirmatory]
View
12
[SID144194411]
AC50_uM SA5-Pax8: Cytotoxicity IOSE-T80 Measured in Cell-Based System Using Plate Reader - 7054-07_Inhibitor_Dose_DryPowder_Activity [AID743045, Type: confirmatory]
View
13
[SID144194411]
AC50_uM SA6-Pax8: cytotoxicity A2780 Measured in Cell-Based System Using Plate Reader - 7054-08_Inhibitor_Dose_DryPowder_Activity [AID743046, Type: confirmatory]
View
14
[SID144194411]
DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
View
15
[SID144194411]
Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_SinglePoint_HTS_Activity [AID651661, Type: screening]
View
16
[SID144194411]
7011-01_Antagonist_SinglePoint_HTS_Activity [AID720647, Type: screening]
View
17
[SID144194411]
HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate Reader - 7056-01_Inhibitor_SinglePoint_HTS_Activity [AID720706, Type: screening]
View
18
[SID144194411]
AC50_uM Counterscreen:CMV reporter Measured in Cell-Based System Using Plate Reader - 7054-04_Inhibitor_Dose_DryPowder_Activity [AID743020, Type: confirmatory]
View
19
[SID144194411]
AC50_uM PAX8: non-specific cytotoxicity Measured in Cell-Based System Using Plate Reader - 7054-05_Inhibitor_Dose_DryPowder_Activity [AID743021, Type: confirmatory]
View
20
[SID144194411]
AC50_uM PAX8: PAX8-dependent cytoxicity Measured in Cell-Based System Using Plate Reader - 7054-06_Inhibitor_Dose_CherryPick_Activity [AID687029, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
View