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MLS004342426 (CID 60159039) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(33)
 
 
Top Targets:
ZnMc TACE lik..(6)
 
 
 
PI-PLCc gamma(3)
 
 
 
PI-PLCc beta3(3)
 
 
 
NR DBD CAR(3)
 
 
FReD(2)
 
 
BioAssay Types:
Screening(33)
 
 
 
Confirmatory(4)
 
 
BioActivity Types:
IC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 36    Data Row: 37   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144096940]
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1). [AID720700, Type: screening]Phospholipase C, gamma 1 [Homo sapiens] [gi:223459640]
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2
[SID144096940]
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM10. [AID720582, Type: screening]ADAM10 [Homo sapiens] [gi:2393947]
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3
[SID144096940]
Counterscreen for inhibitors of phospholipase C isozymes (PLC-B3): Fluorescence-based biochemical high throughput assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1) [AID743258, Type: screening]Phospholipase C, gamma 1 [Homo sapiens] [gi:223459640]
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4
[SID144096940]
Fluorescence-based biochemical high throughput confirmation assay to identify inhibitors of phospholipase C isozymes (PLC-B3) [AID743261, Type: screening]Phospholipase C, beta 3 (phosphatidylinositol-specific) [Homo sapiens] [gi:148745659]
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5
[SID144096940]
IC50 45.064Counterscreen for inhibitors of phospholipase C isozymes (PLC-B3): Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1) [AID743329, Type: confirmatory]Phospholipase C, gamma 1 [Homo sapiens] [gi:223459640]
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6
[SID144096940]
IC50 47.216Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of phospholipase C isozymes (PLC-B3) [AID743328, Type: confirmatory]Phospholipase C, beta 3 (phosphatidylinositol-specific) [Homo sapiens] [gi:148745659]
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7
[SID144096940]
IC50 69.562Counterscreen for exosite inhibitors of ADAM10: QFRET-based biochemical high throughput dose response assay to identify inhibitors of ADAM17 [AID743253, Type: confirmatory]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
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8
[SID144096940]
IC50 69.562QFRET-based biochemical high throughput dose response assay to identify exosite inhibitors of ADAM10. [AID743254, Type: confirmatory]ADAM10 [Homo sapiens] [gi:2393947]
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9
[SID144096940]
TRFRET-based cell-based primary high throughput screening assay to identify inhibitors of cell surface Prion Protein (PRPC) [AID720596, Type: screening]major prion protein preproprotein [Homo sapiens] [gi:4506113]
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10
[SID144096940]
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM17. [AID720648, Type: screening]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
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11
[SID144096940]
Epi Absorbance-based biochemical primary high throughput screening assay to identify inhibitors of human tyrosyl-DNA phosphodiesterase 2 (TDP2) [AID720702, Type: screening]tyrosyl-DNA phosphodiesterase 2 [Homo sapiens] [gi:23510348]
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12
[SID144096940]
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3). [AID720704, Type: screening]Phospholipase C, beta 3 (phosphatidylinositol-specific) [Homo sapiens] [gi:148745659]
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13
[SID144096940]
QFRET-based biochemical high throughput primary assay to identify inhibitors of human group III secreted phospholipase A2 enzyme (HGIII-sPLA2) [AID743126, Type: screening]phospholipase A2, group III [Homo sapiens] [gi:119580345]
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14
[SID144096940]
QFRET-based biochemical high throughput confirmation assay to identify exosite inhibitors of ADAM10. [AID743208, Type: screening]ADAM10 [Homo sapiens] [gi:2393947]
View
15
[SID144096940]
Counterscreen for exosite inhibitors of ADAM10: QFRET-based biochemical high throughput screening assay to identify inhibitors of ADAM17 [AID743214, Type: screening]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
View
16
[SID164337837]
HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate Reader - 7056-01_Inhibitor_SinglePoint_HTS_Activity [AID720706, Type: screening]
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17
[SID164337837]
High Content Cell-Based Imaging Primary HTS to Identify Small Molecules Involved in X-Chromosome Reactivation and Reprogramming Measured in Cell-Based System Using Imaging - 7015-01_Activator_SinglePoint_HTS_Activity_Set2 [AID743238, Type: screening]
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18
[SID164337837]
Inhibition of Alexa 488-Fibronectin deposition #on AH1F cell monolayers Measured in Cell-Based System Using Plate Reader - 7059-01_Inhibitor_SinglePoint_HTS_Activity [AID743247, Type: screening]
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19
[SID164337837]
Luminescent GLuc Reporter Gene Assay Primary HTS to Identify Small Molecule Activator of Glucose Dependent Insulin Secretion Measured in Cell-Based System Using Plate Reader - 7055-01_Activator_SinglePoint_HTS_Activity [AID743287, Type: screening]
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20
[SID144096940]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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