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Progesterone (CID 5994) - Compound BioActivity Data
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BioActivity Outcomes:
Active(283)
 
 
Inactive(2212)
 
 
Inconclusive(539)
 
 
Unspecified(680)
 
 
Top Targets:
7tm 4(139)
 
 
 
 
NR LBD ER(55)
 
 
 
 
 
NR LBD PPAR(48)
 
 
 
NR LBD AR(45)
 
 
 
 
 
NR LBD PR(42)
 
 
 
 
BioAssay Types:
Confirmatory(1379)
 
 
 
 
 
Screening(1099)
 
 
 
 
Literature(466)
 
 
 
 
 
Summary(64)
 
 
 
 
BioActivity Types:
Potency(1045)
 
 
 
 
 
IC50(269)
 
 
 
 
EC50(45)
 
 
 
 
Ki(39)
 
 
 
 
Kd(14)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2039    Data Row: 3714   Total Pages: 186   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103175608]
EC50 0.0001Activation of progesterone receptor in human T47D cells after 20 hrs by PRE-tagged luciferase reporter gene assay [AID469431, Type: Literature]Progesterone receptor [gi:90110048]
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2
[SID103175608]
IC50 0.0002Binding affinity to progesterone receptor [AID569787, Type: Literature]
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3
[SID103175608]
Kd 0.00039Affinity for recombinant Mineralocorticoid receptor [AID126283, Type: Literature]Mineralocorticoid receptor [gi:126885]
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4
[SID103175608]
EC50 0.0005Agonist activity at human progesterone receptor [AID339656, Type: Literature]Progesterone receptor [gi:90110048]
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5
[SID103175608]
EC50 0.0009Effective concentration on alkaline phosphatase activity in human T47D breast carcinoma cell line. [AID208678, Type: Literature]Progesterone receptor [gi:90110048]
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6
[SID103175608]
EC50 0.0009Activity at progesterone receptor assessed as alkaline phosphatase activity in human T47D cells [AID387085, Type: Literature]Progesterone receptor [gi:90110048]
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7
[SID103175608]
EC50 0.00092Effective concentration against PR (progesterone receptor) [AID161810, Type: Literature]Progesterone receptor [gi:90110048]
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8
[SID103175608]
EC50 0.00092Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell line [AID161815, Type: Literature]
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9
[SID46391718]
Kd 0.001Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain L, Three-Dimensional Structure Of An Anti-Steroid Fab' And Progesterone-Fab' Complex [gi:442824]
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10
[SID46391718]
Kd 0.001Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain L, Three-Dimensional Structure Of An Anti-Steroid Fab' And Progesterone-Fab' Complex [gi:442824]
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11
[SID46391718]
Kd 0.001Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain H, Three-Dimensional Structure Of An Anti-Steroid Fab' And Progesterone-Fab' Complex [gi:442825]
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12
[SID46391718]
Kd 0.001Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain H, Three-Dimensional Structure Of An Anti-Steroid Fab' And Progesterone-Fab' Complex [gi:442825]
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13
[SID103175608]
EC50 0.0015Effective concentration for half-maximal activation of human progesterone receptor expressed in CV-1 cells [AID162605, Type: Literature]Progesterone receptor [gi:90110048]
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14
[SID103175608]
EC50 0.0018Human progesterone receptor (hPR) agonist activity in T47D human breast cancer cell line [AID161816, Type: Literature]
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15
[SID103175608]
EC50 0.0018Agonistic activity against human progesterone receptor in T47D breast cancer cells [AID161789, Type: confirmatory]
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16
[SID103175608]
EC50 0.0018Agonistic activity by cotransfection assay against human Progesterone receptor in T47D cells [AID161796, Type: Literature]
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17
[SID103175608]
EC50 0.0022Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activity [AID343211, Type: Literature]Progesterone receptor [gi:90110048]
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18
[SID103175608]
EC50 0.00289Agonistic activity was measured for modulation of hPR-B (human progesterone receptor) in co-transfected CV-1 cells. [AID161792, Type: Literature]Progesterone receptor [gi:90110048]
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19
[SID103175608]
EC50 0.0029Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell [AID47046, Type: Literature]Progesterone receptor [gi:90110048]
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20
[SID103175608]
EC50 0.0029Human progesterone receptor (hPR) agonist activity expressed in CV-1 cells [AID161819, Type: Literature]Progesterone receptor [gi:90110048]
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