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BioActivity Data for Compound Sucrose (CID 5988)

BioActivity Outcomes:
Active(6)
 
 
Inactive(388)
 
 
Inconclusive(15)
 
 
Unspecified(45)
 
 
Top Targets:
NR LBD PPAR(23)
 
 
NR LBD ER(23)
 
 
 
NR LBD AR(23)
 
 
 
NR LBD GR(14)
 
 
NR LBD TR(13)
 
 
 
BioAssay Types:
Confirmatory(254)
 
 
 
Literature(112)
 
 
 
 
Summary(73)
 
 
 
Screening(2)
 
 
BioAssay Categories:
In vivo(17)
 
 
Biochemical(2)
 
 
 
Toxicity(27)
 
 
 
 
ADME(26)
 
 
Cell-based(2)
 
 
 
BioActivity Types:
Potency(312)
 
 
 
Kd(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 220    Data Row: 454   Total Pages: 23   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46391420]
Kd 15000Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Maltoporin Sucrose Complex [gi:3114531]
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2
[SID46391420]
Kd 15000Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Maltoporin Sucrose Complex [gi:3114531]
View
3
[SID46391420]
Kd 15000Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Maltoporin Sucrose Complex [gi:3114532]
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4
[SID46391420]
Kd 15000Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Maltoporin Sucrose Complex [gi:3114532]
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5
[SID46391420]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Maltoporin Sucrose Complex [gi:3114531]
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6
[SID103557064]
Antihemolytic activity against hypotonic hemolysis in Wistar rat erythrocytes at 0.1 to 100 uM after 10 mins [AID698549, Type: Literature]
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7
[SID144205646]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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8
[SID103557064]
Sensory evaluation was done for sweetness at a concentration of 100000 p.p.m. against compound potency calculated on weight basis. [AID90224, Type: Literature]
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9
[SID103557064]
Sensory evaluation was done for sweetness at a concentration of 100000 p.p.m. against sample intensity relative to 10% sucrose. [AID89762, Type: Literature]
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10
[SID103557064]
Ability to bind to guinea pig atrial homogenate [AID78477, Type: Literature]
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11
[SID103557064]
Partition coefficient (logP) [AID26811, Type: Literature]
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12
[SID103557064]
Ability to bind to human serum albumin (HSA) [AID91480, Type: Literature]
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13
[SID103557064]
Time for the sweetness intensity to decline to half maximal [AID24032, Type: Literature]
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14
[SID103557064]
Sensory evaluation was done at a concentration of 100000 p.p.m. against other properties. [AID90258, Type: Literature]
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15
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse brain 4th ventricle choroid plexus assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369784, Type: Literature]
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16
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse pineal gland assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369785, Type: Literature]
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17
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse pituitary gland assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369786, Type: Literature]
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18
[SID103557064]
Biodistribution in FVB Mdr1a/Mdr1b deficient mouse frontal cortex assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369787, Type: Literature]
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19
[SID103557064]
Biodistribution in FVB Mdr1a/Mdr1b deficient mouse caudate putamen assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369788, Type: Literature]
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20
[SID103557064]
Biodistribution in FVB Mdr1a/Mdr1b deficient mouse hyphalamus assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369789, Type: Literature]
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