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Sucrose (CID 5988) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(354)
 
 
Inconclusive(18)
 
 
Unspecified(45)
 
 
Top Targets:
NR LBD ER(23)
 
 
 
NR LBD PPAR(23)
 
 
 
NR LBD AR(23)
 
 
 
NR LBD GR(14)
 
 
NR LBD TR(13)
 
 
 
BioAssay Types:
Confirmatory(233)
 
 
 
Literature(108)
 
 
 
 
Summary(63)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(281)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 203    Data Row: 419   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103557064]
Antihemolytic activity against hypotonic hemolysis in Wistar rat erythrocytes at 0.1 to 100 uM after 10 mins [AID698549, Type: Literature]
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2
[SID46391420]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Maltoporin Sucrose Complex [gi:3114531]
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3
[SID103557064]
Permeability across human Caco-2 cells [AID455986, Type: Literature]
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4
[SID103557064]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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5
[SID103557064]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature]
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6
[SID103557064]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature]
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7
[SID103557064]
Antimicrobial activity against Staphylococcus aureus ATCC 9144 after 24 hrs using thiazoyl blue by agar overlay bioautography method [AID614100, Type: Literature]
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8
[SID103557064]
Antimicrobial activity against Bacillus subtilis ATCC 6633 after 24 hrs using thiazoyl blue by agar overlay bioautography method [AID614101, Type: Literature]
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9
[SID103557064]
Antimicrobial activity against Pseudomonas aeruginosa NCTC 10332 after 24 hrs using thiazoyl blue by agar overlay bioautography method [AID614102, Type: Literature]
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10
[SID103557064]
Antimicrobial activity against Candida albicans ATCC 10231 after 24 hrs using thiazoyl blue by agar overlay bioautography method [AID614103, Type: Literature]
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11
[SID103557064]
Antimicrobial activity against Escherichia coli ATCC 11229 after 24 hrs using thiazoyl blue by agar overlay bioautography method [AID614104, Type: Literature]
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12
[SID144205646]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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13
[SID26757665]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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14
[SID103557064]
Partition coefficient (logP) [AID23672, Type: Literature]
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15
[SID103557064]
Time for the sweetness intensity to decline to half maximal [AID24032, Type: Literature]
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16
[SID103557064]
Partition coefficient (logP) [AID26811, Type: Literature]
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17
[SID103557064]
Ability to bind to guinea pig atrial homogenate [AID78477, Type: Literature]
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18
[SID103557064]
Sensory evaluation was done for sweetness at a concentration of 100000 p.p.m. against sample intensity relative to 10% sucrose. [AID89762, Type: Literature]
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19
[SID103557064]
Sensory evaluation was done for sweetness at a concentration of 100000 p.p.m. against compound potency calculated on a molar basis . [AID90086, Type: Literature]
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20
[SID103557064]
Sensory evaluation was done for sweetness at a concentration of 100000 p.p.m. against compound potency calculated on weight basis. [AID90224, Type: Literature]
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21
[SID103557064]
Sensory evaluation was done at a concentration of 100000 p.p.m. against other properties. [AID90258, Type: Literature]
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22
[SID103557064]
Sensory evaluation was done at a concentration of 100000 p.p.m. against property of bitterness. [AID90259, Type: Literature]
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23
[SID103557064]
Sensory evaluation was done at a concentration of 100000 p.p.m. against property of sweetness. [AID90260, Type: Literature]
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24
[SID103557064]
Ability to bind to human serum albumin (HSA) [AID91480, Type: Literature]
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25
[SID103557064]
The capillary permeability of radioligand was measured in Rat brain [AID189629, Type: Literature]
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26
[SID103557064]
Permeability coefficient in human skin [AID311367, Type: Literature]
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27
[SID103557064]
Antibacterial activity against Bacillus subtilis ATCC 6633 after 48 hrs by silica gel plate-based INT-formazan method [AID337692, Type: Literature]
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28
[SID103557064]
Antibacterial activity against Escherichia coli ATCC 25922 after 48 hrs by silica gel plate-based INT-formazan method [AID337693, Type: Literature]
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29
[SID103557064]
Biodistribution in perfused wild type FVB Mdr1a/Mdr1b positive mouse choroid plexus assessed as tritiated drug level after 2.5 mins relative to control [AID369769, Type: Literature]
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30
[SID103557064]
Biodistribution in BALB/c mouse thalamus assessed as tritiated drug level at 150 uM perfusion after 10 mins by capillary depletion assay in presence of phenylarsine ocide [AID369774, Type: Literature]
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31
[SID103557064]
Drug uptake in BALB/c mouse assessed as tritiated drug level at 5 ml/min perfusion after 10 min relative to [14C]sucrose [AID369781, Type: Literature]
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32
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse caudate putamen assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369782, Type: Literature]
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33
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse hypothalamus assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369783, Type: Literature]
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34
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse brain 4th ventricle choroid plexus assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369784, Type: Literature]
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35
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse pineal gland assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369785, Type: Literature]
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36
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse pituitary gland assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369786, Type: Literature]
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37
[SID103557064]
Biodistribution in FVB Mdr1a/Mdr1b deficient mouse frontal cortex assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369787, Type: Literature]
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38
[SID103557064]
Biodistribution in FVB Mdr1a/Mdr1b deficient mouse caudate putamen assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369788, Type: Literature]
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39
[SID103557064]
Biodistribution in FVB Mdr1a/Mdr1b deficient mouse hypothalamus assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369789, Type: Literature]
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40
[SID103557064]
Biodistribution in FVB Mdr1a/Mdr1b deficient mouse thalamus assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369790, Type: Literature]
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41
[SID103557064]
Biodistribution in FVB Mdr1a/Mdr1b deficient mouse cerebellum assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369791, Type: Literature]
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42
[SID103557064]
Biodistribution in perfused FVB Mdr1a/Mdr1b deficient mouse choroid plexus assessed as tritiated drug level after 2.5 mins relative to control [AID369793, Type: Literature]
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43
[SID103557064]
Biodistribution in perfused wild type FVB Mdr1a/Mdr1b positive mouse choroid plexus assessed as tritiated drug level after 30 mins relative to control [AID369795, Type: Literature]
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44
[SID103557064]
Biodistribution in perfused FVB Mdr1a/Mdr1b deficient mouse choroid plexus assessed as tritiated drug level after 30 mins relative to control [AID369797, Type: Literature]
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45
[SID103557064]
Biodistribution in perfused BALB/c mouse choroid plexus assessed as tritiated drug level after 2.5 mins in presence of DMSO relative to control [AID369799, Type: Literature]
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46
[SID103557064]
Biodistribution in perfused BALB/c mouse choroid plexus assessed as tritiated drug level after 2.5 mins in presence of phenylarsine oxide relative to control [AID369800, Type: Literature]
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47
[SID103557064]
Partition coefficient, log D of the compound [AID369805, Type: Literature]
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48
[SID26757665]
Potency 0.0405S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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49
[SID26757665]
Potency S16 Schwann cell PMP22 intronic element beta-lactamase assay [AID624044, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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50
[SID26757665]
Potency qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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