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BioActivity Data for Compound Sucrose (CID 5988)

BioActivity Outcomes:
Active(6)
 
 
Inactive(382)
 
 
Inconclusive(13)
 
 
Unspecified(45)
 
 
Top Targets:
NR LBD PPAR(23)
 
 
NR LBD ER(23)
 
 
 
NR LBD AR(23)
 
 
 
NR LBD GR(14)
 
 
NR LBD TR(13)
 
 
 
BioAssay Types:
Confirmatory(250)
 
 
 
Literature(112)
 
 
 
 
Summary(69)
 
 
 
Screening(2)
 
 
BioAssay Categories:
In vivo(17)
 
 
Biochemical(2)
 
 
 
Toxicity(27)
 
 
 
 
ADME(26)
 
 
Cell-based(2)
 
 
 
BioActivity Types:
Potency(304)
 
 
 
Kd(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 216    Data Row: 446   Total Pages: 23   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46391420]
Kd 15000Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Maltoporin Sucrose Complex [gi:3114531]
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2
[SID46391420]
Kd 15000Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Maltoporin Sucrose Complex [gi:3114531]
View
3
[SID46391420]
Kd 15000Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Maltoporin Sucrose Complex [gi:3114532]
View
4
[SID46391420]
Kd 15000Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Maltoporin Sucrose Complex [gi:3114532]
View
5
[SID103557064]
Antihemolytic activity against hypotonic hemolysis in Wistar rat erythrocytes at 0.1 to 100 uM after 10 mins [AID698549, Type: Literature]
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6
[SID46391420]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Maltoporin Sucrose Complex [gi:3114531]
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7
[SID103557064]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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8
[SID144205646]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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9
[SID103557064]
Antibacterial activity against Bacillus subtilis ATCC 6633 after 48 hrs by silica gel plate-based INT-formazan method [AID337692, Type: Literature]
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10
[SID103557064]
Biodistribution in perfused wild type FVB Mdr1a/Mdr1b positive mouse choroid plexus assessed as tritiated drug level after 2.5 mins relative to control [AID369769, Type: Literature]
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11
[SID103557064]
Biodistribution in BALB/c mouse thalamus assessed as tritiated drug level at 150 uM perfusion after 10 mins by capillary depletion assay in presence of phenylarsine ocide [AID369774, Type: Literature]
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12
[SID103557064]
Sensory evaluation was done for sweetness at a concentration of 100000 p.p.m. against compound potency calculated on a molar basis. [AID90086, Type: Literature]
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13
[SID103557064]
Drug uptake in BALB/c mouse assessed as tritiated drug level at 5 ml/min perfusion after 10 min relative to [14C]sucrose [AID369781, Type: Literature]
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14
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse caudate putamen assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369782, Type: Literature]
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15
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse hyphalamus assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369783, Type: Literature]
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16
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse brain 4th ventricle choroid plexus assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369784, Type: Literature]
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17
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse pineal gland assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369785, Type: Literature]
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18
[SID103557064]
Biodistribution in wild type FVB Mdr1a/Mdr1b positive mouse pituitary gland assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369786, Type: Literature]
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19
[SID103557064]
Biodistribution in FVB Mdr1a/Mdr1b deficient mouse frontal cortex assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369787, Type: Literature]
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20
[SID103557064]
Biodistribution in FVB Mdr1a/Mdr1b deficient mouse caudate putamen assessed as tritiated drug level at 150 uM perfusion after 30 mins by capillary depletion assay [AID369788, Type: Literature]
View