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cetrimonium (CID 5974) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(135)
 
 
Inactive(149)
 
 
Inconclusive(172)
 
 
Unspecified(69)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD ER(16)
 
 
 
 
NR LBD AR(16)
 
 
 
 
NR LBD TR(12)
 
 
 
 
NR LBD VDR(12)
 
 
 
BioAssay Types:
Confirmatory(260)
 
 
 
 
 
Literature(155)
 
 
 
 
 
Summary(48)
 
 
 
 
Screening(6)
 
 
BioActivity Types:
Potency(290)
 
 
 
 
IC50(11)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 340    Data Row: 525   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26748720]
Potency 0.1458qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID144205649]
Potency-Replicate_1 0.4731qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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3
[SID144205649]
Potency-Replicate_1 0.5956qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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4
[SID103263607]
IC50 0.75Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay [AID438785, Type: Literature]
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5
[SID103263607]
IC50 0.76Cytotoxicity against human A549 cells after 72 hrs by MTT assay [AID438786, Type: Literature]
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6
[SID144211170]
Potency-Replicate_1 0.7696qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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7
[SID103263607]
IC50 0.8In vitro activity against Plasmodium falciparum [AID151197, Type: Literature]
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8
[SID103263607]
IC50 0.8Inhibitory activity against Plasmodium falciparum [AID158688, Type: Literature]
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9
[SID26748720]
Potency 0.8199qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID144205649]
Potency-Replicate_1 0.8413qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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11
[SID144205649]
Potency-Replicate_1 0.8413qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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12
[SID144211170]
Potency-Replicate_1 0.9689qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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13
[SID144211170]
Potency-Replicate_1 0.9689qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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14
[SID144205649]
Potency 1.0593qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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15
[SID144205649]
Potency 1.1886qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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16
[SID26757701]
Potency 1.2589qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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17
[SID103263607]
IC50 1.98Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay [AID438781, Type: Literature]
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18
[SID26757701]
Potency 2.6855Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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19
[SID103263607]
IC50 3.25Cytotoxicity against human CCRF-CEM cells after 72 hrs by MTT assay [AID438782, Type: Literature]
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20
[SID144211170]
Potency-Replicate_1 3.8895qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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21
[SID103263607]
MIC 4Antibacterial activity against 5 x 10'5 CFU/mL Enterococcus faecalis ATCC 29212 after 72 hrs by CLSI M07-A8 broth microdilution method [AID613553, Type: Literature]
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22
[SID103263607]
MIC 4Antibacterial activity against 5 x 10'5 CFU/mL Staphylococcus aureus subsp. aureus ATCC 29213 after 72 hrs by CLSI M07-A8 broth microdilution method [AID613554, Type: Literature]
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23
[SID103263607]
IC50 4.1Cytotoxicity against human HeLa cells after 72 hrs by MTT assay [AID438783, Type: Literature]
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24
[SID103263607]
IC50 4.37Concentration required against dynamin-1 GTPase activity of sheep brain. [AID63727, Type: Literature]
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25
[SID103263607]
IC50 4.5Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay [AID438784, Type: Literature]
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26
[SID26757701]
Potency 4.7755Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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27
[SID144205649]
Potency-Replicate_1 6.6824qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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28
[SID103263607]
IC50 7.69Inhibition of synthetic amyloid beta-42 oligomerization by ELISA [AID322955, Type: Literature]
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29
[SID144211170]
Potency-Replicate_1 7.6959qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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30
[SID26757701]
Potency 8.0875S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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31
[SID144205649]
Ratio Potency (uM) 8.15772qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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32
[SID26748720]
Potency 8.9125qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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33
[SID144205649]
Potency-Replicate_1 9.4392qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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34
[SID144205649]
Potency-Replicate_1 9.5205qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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35
[SID103263607]
MIC 10Antimicrobial activity against Staphylococcus epidermidis after 24 hrs [AID420458, Type: Literature]
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36
[SID144211170]
Ratio Potency (uM) 10.9622qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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37
[SID26748720]
Potency 11.2202qHTS Assay for Lipid Storage Modulators [AID1519, Type: confirmatory]
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38
[SID144205649]
Potency-Replicate_1 11.9856qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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39
[SID144205649]
Ratio Potency (uM) 12.8312qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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40
[SID170465714]
Potency-Replicate_1 13.3322qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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41
[SID144205649]
Potency-Replicate_1 13.3332qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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42
[SID144211170]
Potency-Replicate_1 13.6854qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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43
[SID170465714]
Potency-Replicate_1 16.7842qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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44
[SID144205649]
Potency-Replicate_1 16.7855qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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45
[SID170465714]
Potency-Replicate_1 18.8322qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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46
[SID103263607]
MIC 20Antimicrobial activity against Bordetella bronchiseptica after 24 hrs [AID420451, Type: Literature]
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47
[SID103263607]
IC50 21Antimicrobial activity against Plasmodium falciparum [AID496819, Type: Literature]
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48
[SID170465714]
Potency-Replicate_1 21.13qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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49
[SID170465714]
Potency-Replicate_1 21.13qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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50
[SID144205649]
Potency-Replicate_1 21.3138qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
View