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BioActivity Data for Compound Cytosine (CID 597)

BioActivity Outcomes:
Active(2)
 
 
Inactive(571)
 
 
Inconclusive(7)
 
 
Unspecified(6)
 
 
Top Targets:
7tm 4(35)
 
 
NR LBD PPAR(8)
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD VDR(5)
 
 
 
BioAssay Types:
Screening(349)
 
 
 
Confirmatory(183)
 
 
 
 
Summary(27)
 
 
 
Literature(16)
 
 
 
BioAssay Categories:
In vivo(6)
 
 
 
Biochemical(108)
 
 
 
Toxicity(11)
 
 
Cell-based(115)
 
 
 
Organism-base..(16)
 
 
 
BioActivity Types:
Potency(189)
 
 
 
 
IC50(12)
 
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 544    Data Row: 586   Total Pages: 30   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56322619]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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2
[SID56322619]
Luminescence Microorganism Primary HTS to Identify Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID2716, Type: screening]
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3
[SID103179050]
Aqueous solubility [AID19262, Type: Literature]
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4
[SID103179050]
The concentration required to inhibit the growth of L-1210 leukemic cells was evaluated [AID97843, Type: Literature]
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5
[SID103179050]
The concentration required (hypoxanthine+uridine) to inhibit the growth of L-1210 leukemic cells was evaluated [AID97848, Type: Literature]
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6
[SID103179050]
IC50 Irreversible inhibition of Walker 256 rat tumor deoxycytidine kinase by [3H]deoxycytidine binding assay [AID1145970, Type: Literature]Deoxycytidine kinase [gi:1352235]
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7
[SID103179050]
Irreversible inhibition of Walker 256 rat tumor deoxycytidine kinase assessed as ratio of V0/V1 by [3H]deoxycytidine binding assay [AID1145972, Type: Literature]Deoxycytidine kinase [gi:1352235]
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8
[SID56322619]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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9
[SID56322619]
Potency 1.7783A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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10
[SID56322619]
AC50_uM 420Luminescence Whole-Organism Secondary Assay to Identify Compounds Inducing Growth of Temperature Sensitive Mutant Burl-1 [AID463199, Type: confirmatory]
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11
[SID56322619]
AC50_uM 420Luminescence Whole-Organism Dose Retest to Confirm Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID463204, Type: confirmatory]
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12
[SID56322619]
uHTS identification of small molecule activators of the adaptive arm of the Unfolded Protein response via a luminescent-based reporter assay [AID463104, Type: screening]
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13
[SID56322619]
Fluorescence-based counterscreen for orexin 1 receptor (OX1R) antagonists: cell-based assay to identify antagonists of the parental CHO cell line [AID463079, Type: screening]
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14
[SID144212456]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743241, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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15
[SID56322619]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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16
[SID56322619]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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17
[SID56322619]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ LAP4_MLPCN. [AID2023, Type: screening]LAP4 [Saccharomyces cerevisiae] [gi:486173]
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18
[SID56322619]
Primary cell-based high-throughput screening assay for identification of compounds that protect hERG from block by proarrhythmic agents [AID1511, Type: screening]putative potassium channel subunit [Homo sapiens] [gi:487738]
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19
[SID56322619]
Potency qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease [AID2101, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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20
[SID56322619]
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL). [AID2129, Type: screening]bcl-xL [Homo sapiens] [gi:510901]
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