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BioActivity Data for Compound Cytosine (CID 597)

BioActivity Outcomes:
Active(2)
 
 
Inactive(559)
 
 
Inconclusive(6)
 
 
Unspecified(4)
 
 
Top Targets:
7tm 4(35)
 
 
NR LBD PPAR(8)
 
 
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
Esterase lipa..(5)
 
 
BioAssay Types:
Screening(349)
 
 
 
Confirmatory(174)
 
 
 
 
Summary(24)
 
 
 
Literature(14)
 
 
 
BioActivity Types:
Potency(177)
 
 
 
 
IC50(11)
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 529    Data Row: 571   Total Pages: 29   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56322619]
Luminescence Microorganism Primary HTS to Identify Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID2716, Type: screening]
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2
[SID56322619]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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3
[SID103179050]
Aqueous solubility [AID19262, Type: Literature]
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4
[SID103179050]
The concentration required to inhibit the growth of L-1210 leukemic cells was evaluated [AID97843, Type: Literature]
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5
[SID103179050]
The concentration required (hypoxanthine+uridine) to inhibit the growth of L-1210 leukemic cells was evaluated [AID97848, Type: Literature]
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6
[SID56322619]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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7
[SID56322619]
Potency 1.7783A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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8
[SID56322619]
AC50_uM 420Luminescence Whole-Organism Secondary Assay to Identify Compounds Inducing Growth of Temperature Sensitive Mutant Burl-1 [AID463199, Type: confirmatory]
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9
[SID56322619]
AC50_uM 420Luminescence Whole-Organism Dose Retest to Confirm Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID463204, Type: confirmatory]
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10
[SID56322619]
Phenotypic HTS multiplex for antifungal efflux pump inhibitors [AID485275, Type: screening]
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11
[SID56322619]
Potency qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
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12
[SID56322619]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_SinglePoint_HTS_Activity [AID488862, Type: screening]
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13
[SID56322619]
IC50 Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
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14
[SID56322619]
IC50 Primary and Confirmatory Screening for Inhibitors of Bacterial Capsule Biogenesis [AID488966, Type: confirmatory]
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15
[SID88071]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Madison 109 Lung Carcinoma (intramuscular) in BALB/CM mice [AID302, Type: other]
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16
[SID88071]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID330, Type: other]
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17
[SID56322619]
MLPCN Ras selective lethality-BJeLR viability [AID1554, Type: screening]
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18
[SID56322619]
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493008, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
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19
[SID56322619]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493244, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
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20
[SID56322619]
uHTS identification of agonists of the CRF-binding protein and CRF-R2 receptor complex [AID588473, Type: screening]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
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