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BioActivity Data for Compound Cytosine (CID 597)

BioActivity Outcomes:
Active(2)
 
 
Inactive(559)
 
 
Inconclusive(6)
 
 
Unspecified(6)
 
 
Top Targets:
7tm 4(35)
 
 
NR LBD PPAR(8)
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
bZIP NFE2-lik..(5)
 
 
BioAssay Types:
Screening(349)
 
 
 
Confirmatory(174)
 
 
 
 
Summary(24)
 
 
 
Literature(16)
 
 
 
BioActivity Types:
Potency(177)
 
 
 
 
IC50(12)
 
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 531    Data Row: 573   Total Pages: 29   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56322619]
Luminescence Microorganism Primary HTS to Identify Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID2716, Type: screening]
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2
[SID56322619]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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3
[SID103179050]
Aqueous solubility [AID19262, Type: Literature]
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4
[SID103179050]
The concentration required to inhibit the growth of L-1210 leukemic cells was evaluated [AID97843, Type: Literature]
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5
[SID103179050]
The concentration required (hypoxanthine+uridine) to inhibit the growth of L-1210 leukemic cells was evaluated [AID97848, Type: Literature]
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6
[SID56322619]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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7
[SID103179050]
IC50 Irreversible inhibition of Walker 256 rat tumor deoxycytidine kinase by [3H]deoxycytidine binding assay [AID1145970, Type: Literature]Deoxycytidine kinase [gi:1352235]
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8
[SID103179050]
Irreversible inhibition of Walker 256 rat tumor deoxycytidine kinase assessed as ratio of V0/V1 by [3H]deoxycytidine binding assay [AID1145972, Type: Literature]Deoxycytidine kinase [gi:1352235]
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9
[SID56322619]
Potency 1.7783A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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10
[SID56322619]
AC50_uM 420Luminescence Whole-Organism Dose Retest to Confirm Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID463204, Type: confirmatory]
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11
[SID56322619]
AC50_uM 420Luminescence Whole-Organism Secondary Assay to Identify Compounds Inducing Growth of Temperature Sensitive Mutant Burl-1 [AID463199, Type: confirmatory]
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12
[SID56322619]
uHTS luminescence assay for the identification of chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation [AID435003, Type: screening]
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13
[SID56322619]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Beta Cell Apoptosis. [AID435005, Type: screening]
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14
[SID56322619]
uHTS luminescence assay for the identification of chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation [AID435022, Type: screening]
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15
[SID56322619]
Counterscreen for inhibitors of AddAB: absorbance-based bacterial cell-based high throughput screening assay to identify inhibitors of bacterial viability [AID449728, Type: screening]
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16
[SID56322619]
IC50 High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media [AID449762, Type: confirmatory]
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17
[SID56322619]
uHTS identification of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay [AID449763, Type: screening]
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18
[SID56322619]
IC50 A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) [AID2391, Type: confirmatory]
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19
[SID56322619]
Potency qHTS Assay for Lipid Storage Modulators in Drosophila S3 Cells [AID2685, Type: confirmatory]
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20
[SID56322619]
A yeast HTS for caloric restriction mimetics that inhibit age-related superoxide [AID2690, Type: screening]
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