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Aspartic Acid (CID 5960) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inactive(281)
 
 
Inconclusive(26)
 
 
Unspecified(28)
 
 
Top Targets:
p450(9)
 
 
 
PLN02808(8)
 
 
PLDc mTdp1 2(7)
 
 
HELICc(7)
 
 
 
Tubulin-bindi..(7)
 
 
 
BioAssay Types:
Confirmatory(278)
 
 
 
 
Literature(41)
 
 
 
 
 
Screening(14)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(255)
 
 
 
 
Kd(3)
 
 
EC50(3)
 
 
IC50(2)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 248    Data Row: 343   Total Pages: 18   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103172284]
Kd 0.001Binding affinity to Pyrococcus horikoshii sodium-coupled aspartate transporter L130W mutant fluorescence-based assay in presence of NaCl [AID328865, Type: Literature]
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2
[SID103172284]
Kd 0.002Binding affinity to Pyrococcus horikoshii sodium-coupled aspartate transporter [AID328866, Type: Literature]
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3
[SID103172284]
Kd 0.094Binding affinity to Pyrococcus horikoshii sodium-coupled aspartate transporter by isothermal titration calorimetry in presence of NaCl [AID328869, Type: Literature]
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4
[SID103172284]
IC50 1.638Compound was evaluated for the inhibition of [3H]-CGS-19,755 binding at N-methyl-D-aspartate glutamate receptor [AID144612, Type: Literature]
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5
[SID103172284]
IC50 10Displacement of [3H]CPP from N-methyl-D-aspartate glutamate receptor in rat brain membrane [AID144456, Type: Literature]
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6
[SID103172284]
Tested in vitro for activation of Human cloned isozyme carbonic anhydrase I (hCA I) [AID50347, Type: Literature]
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7
[SID103172284]
Induction of nitrogen-starved wild type sigma1278b yeast Gap1-mediated trehalose activation at 10 mM [AID500825, Type: Literature]
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8
[SID48415581]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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9
[SID103172284]
EC50 1000Agonistic activity at mGlu6 receptor expressed in CHO cells [AID107251, Type: Literature]
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10
[SID103172284]
EC50 1000Agonistic activity at mGlu1-alpha receptor expressed in CHO cells [AID108645, Type: Literature]
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11
[SID103172284]
EC50 1000Agonistic activity at mGlu2 receptor expressed in CHO cells [AID109003, Type: Literature]
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12
[SID103172284]
Bitter threshold value; NB denotes 'Not bitter' [AID233320, Type: Literature]
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13
[SID103172284]
Permeability coefficient in human skin [AID311367, Type: Literature]
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14
[SID103172284]
Compound was tested for its uptake by the 7800C1 cells [AID166060, Type: Literature]
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15
[SID103172284]
Compound was tested for its uptake by the R5 cells [AID166061, Type: Literature]
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16
[SID11113409]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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17
[SID103172284]
pKa (acid-base dissociation constant) as determined by Avdeef ref: DOI: 10.1002/047145026X [AID781326, Type: Literature]
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18
[SID103172284]
Ischemic myocardial residue fraction of [13N]-labeled amino acid was observed with a single pass uptake technique in open-chest instrumented dogs (control - 14+/-4.2) [AID58928, Type: Literature]
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19
[SID103172284]
Compound was tested for its uptake by the GH4C1 cells [AID73049, Type: Literature]
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20
[SID103172284]
Compound was tested for its uptake by the H4 cells [AID80822, Type: Literature]
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