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BioActivity Data for Compound 4-Nitroquinoline-1-oxide (CID 5955)

BioActivity Outcomes:
Active(9)
 
 
Inactive(1)
 
 
Unspecified(19)
 
 
BioAssay Types:
Literature(20)
 
 
 
 
BioAssay Categories:
Biochemical(3)
 
 
 
Toxicity(8)
 
 
ADME(13)
 
 
Cell-based(3)
 
 
 
BioActivity Types:
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 29    Data Row: 29   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103355242]
IC50 0.00033Inhibitory activity of compound for AA8 cells to reduce cell density by 50% (exposed to compound for 4 hours) [AID45745, Type: Literature]
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2
[SID541575]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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3
[SID541575]
NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
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4
[SID541575]
NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
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5
[SID541575]
NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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6
[SID541575]
NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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7
[SID541575]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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8
[SID103355242]
Binding affinity to Candida albicans CaMdr1p expressed in yeast AD1-8u [AID537735, Type: Literature]
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9
[SID103355242]
Binding affinity to Candida albicans CaCdr1p expressed in yeast AD1-8u [AID537733, Type: Literature]
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10
[SID103355242]
Mutagenic activity in Salmonella Typhimurium TA98 at 2.16 uM after 60 hrs by Ames test in absence of human S9 fraction [AID450174, Type: Literature]
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11
[SID103355242]
Mutagenic activity in Salmonella Typhimurium at 2.16 uM after 60 hrs by Ames test in absence of human S9 fraction [AID450173, Type: Literature]
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12
[SID103355242]
Ratio of CR50 for wild type Bacillus subtilis H17 to CR50 for recombination-deficient Bacillus subtilis M45 [AID1093797, Type: other]
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13
[SID103355242]
Genotoxicity in wild type Bacillus subtilis H17 assessed as growth inhibition [AID1093799, Type: other]
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14
[SID103355242]
Genotoxicity in recombination-deficient Bacillus subtilis M45 assessed as growth inhibition [AID1093798, Type: other]
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15
[SID103355242]
Genotoxicity in human lymphocytes assessed as micronucleated binucleate cells level at 5 ug/mL incubated for 20 hrs measured post 28 hrs recovery in absence of rat liver S9 fraction (Rvb = 0.4%) [AID693071, Type: Literature]
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16
[SID103355242]
Genotoxicity in human lymphocytes assessed as micronucleated binucleate cells level at 2.5 ug/mL incubated for 20 hrs measured post 28 hrs recovery in absence of rat liver S9 fraction (Rvb = 0.3%) [AID693044, Type: Literature]
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17
[SID103355242]
Lipophilicy, log P of the compound [AID1134823, Type: Literature]
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18
[SID103355242]
Carcinogenicity in mouse assessed as tumor development administered sc in left groin 6 times at 10-day interval [AID1134822, Type: Literature]
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19
[SID103355242]
Mutagenic activity in Salmonella typhimurium TA 98 assessed as increase in revertants at 5 ug/plate after 48 hrs by Ames test relative to control [AID661623, Type: Literature]
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20
[SID103355242]
Genotoxicity against Salmonella Typhimurium NM2009 assessed as induction of umu operon expression in presence of rat liver S9 fraction [AID319215, Type: Literature]
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