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Alanine (CID 5950) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(93)
 
 
Inconclusive(3)
 
 
Unspecified(8)
 
 
Top Targets:
p450(9)
 
 
HSD10-like SD..(4)
 
 
PLDc mTdp1 2(3)
 
 
 
Tubulin-bindi..(3)
 
 
IMPase(2)
 
 
BioAssay Types:
Confirmatory(89)
 
 
 
Literature(9)
 
 
 
 
Screening(1)
 
 
BioActivity Types:
Potency(69)
 
 
 
Ki(2)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 95    Data Row: 105   Total Pages: 6   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103182286]
Drug uptake in Escherichia coli ATCC 10536 assessed as membrane localization at 3 uM after 30 mins by confocal microscopic analysis [AID722314, Type: Literature]
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2
[SID103182286]
IC50 198Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 [AID143614, Type: Literature]
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3
[SID103182286]
Ki 2800Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting [AID630741, Type: Literature]Proton-coupled amino acid transporter 1 [gi:51316800]
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4
[SID103182286]
Km 14200Km value for Alanine racemase from Pseudomonas aeruginosa [AID33397, Type: Literature]
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5
[SID103182286]
Tested in vitro for activation of Human cloned isozyme carbonic anhydrase II (hCA II) [AID47753, Type: Literature]
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6
[SID103182286]
Tested in vitro for activation of carbonic anhydrase IV (bCA IV), purified from bovine lung microsomes [AID48116, Type: Literature]
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7
[SID103182286]
Tested in vitro for activation of Human cloned isozyme carbonic anhydrase I (hCA I) [AID50347, Type: Literature]
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8
[SID11113404]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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9
[SID103182286]
Ki TP_TRANSPORTER: inhibition of L-tryptophan uptake in Xenopus laevis oocytes [AID681113, Type: Literature]Monocarboxylate transporter 10 [gi:81871541]
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10
[SID11113404]
qHTS Assay for Inhibitors of PDE-IV [AID607, Type: confirmatory]cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Homo sapiens] [gi:82799486]
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11
[SID11113404]
qHTS Assay for Inhibitors of YjeE [AID605, Type: confirmatory]tRNA threonylcarbamoyladenosine biosynthesis protein TsaE [gi:84028058]
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12
[SID11113404]
Potency Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS [AID504845, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301163]
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13
[SID11113404]
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP) [AID1471, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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14
[SID11113404]
qHTS Assay for Tau Filament Binding [AID596, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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15
[SID11113404]
Potency qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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16
[SID11113404]
Potency qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1468, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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17
[SID11113404]
Potency Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein, partial [Homo sapiens] [gi:118600387]
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18
[SID11113404]
Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) [AID584, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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19
[SID11113404]
Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID585, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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20
[SID11113404]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate [AID2112, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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