Bookmark and Share

BioActivity Data for Compound Carbon Tetrachloride (CID 5943)

BioActivity Outcomes:
Active(6)
 
 
Inactive(550)
 
 
Inconclusive(13)
 
 
Unspecified(2166)
 
 
Top Targets:
7tm 4(33)
 
 
 
NR LBD ER(20)
 
 
 
NR LBD PPAR(20)
 
 
 
NR LBD AR(19)
 
 
 
 
p450(16)
 
 
 
 
BioAssay Types:
Confirmatory(554)
 
 
 
 
 
Literature(76)
 
 
 
Summary(39)
 
 
 
Screening(2)
 
 
BioAssay Categories:
In vitro(132)
 
 
 
In vivo(2024)
 
 
 
Biochemical(133)
 
 
 
 
Toxicity(2098)
 
 
 
ADME(8)
 
 
 
Cell-based(83)
 
 
 
BioActivity Types:
Potency(397)
 
 
 
IC50(117)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2440    Data Row: 2735   Total Pages: 137   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103226142]
IC50 11DRUGMATRIX: CYP450, 2E1 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625250, Type: confirmatory]Cytochrome P450 2E1 [gi:117250]
View
2
[SID48413382]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
View
3
[SID48413382]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
View
4
[SID48413382]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
View
5
[SID48413382]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
6
[SID85229934]
Ligands of peptide (Class A) GPCRs [AID2063, Type: other]
View
7
[SID17389121]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
View
8
[SID103226142]
Literature-mined public compounds from Lowe et al phospholipidosis modelling dataset [AID588208, Type: Literature]
View
9
[SID103226142]
Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset [AID588209, Type: Literature]
View
10
[SID103226142]
Human drug-induced liver injury (DILI) modelling dataset from Ekins et al [AID588210, Type: Literature]
View
11
[SID103226142]
IC50 Cytotoxicity against human HepG2 cells after 24 hrs assessed as inhibition of cell viability by MTT assay [AID592714, Type: Literature]
View
12
[SID103226142]
Octanol-water partition coefficient, log P of the compound [AID603957, Type: Literature]
View
13
[SID103226142]
IC50 DRUGMATRIX: Nicotinic Acetylcholine radioligand binding (ligand: [125I] Epibatidine) [AID625158, Type: confirmatory]
View
14
[SID103226142]
DRUGMATRIX: Phorbol Ester radioligand binding (ligand: [3H] PDBu) [AID625164, Type: other]
View
15
[SID103226142]
IC50 DRUGMATRIX: Phosphodiesterase PDE3 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625165, Type: confirmatory]
View
16
[SID103226142]
IC50 DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625166, Type: confirmatory]
View
17
[SID103226142]
DRUGMATRIX: Platelet-Derived Growth Factor (PDGF) radioligand binding (ligand: [125I] PDGF) [AID625169, Type: other]
View
18
[SID103226142]
IC50 DRUGMATRIX: Potassium Channel [KATP] radioligand binding (ligand: [3H] Glyburide) [AID625170, Type: confirmatory]
View
19
[SID103226142]
DRUGMATRIX: Purinergic P2X radioligand binding (ligand: [3H] alpha, beta-Methylene-ATP) [AID625189, Type: other]
View
20
[SID103226142]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT) [AID625190, Type: confirmatory]
View