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Carbon Tetrachloride (CID 5943) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(549)
 
 
Inconclusive(14)
 
 
Unspecified(2166)
 
 
Top Targets:
NR LBD ER(20)
 
 
 
NR LBD PPAR(20)
 
 
 
NR LBD AR(19)
 
 
 
 
7TM GPCR Srx(17)
 
 
7TM GPCR Srsx(17)
 
 
 
BioAssay Types:
Confirmatory(554)
 
 
 
 
 
Literature(76)
 
 
 
Summary(39)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(397)
 
 
 
IC50(117)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2440    Data Row: 2735   Total Pages: 137   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103226142]
IC50 11DRUGMATRIX: CYP450, 2E1 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625250, Type: confirmatory]Cytochrome P450 2E1 [gi:117250]
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2
[SID48413382]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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3
[SID48413382]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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4
[SID48413382]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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5
[SID85229934]
Ligands of peptide (Class A) GPCRs [AID2063, Type: other]
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6
[SID48413382]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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7
[SID103226142]
IC50 DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol) [AID625206, Type: confirmatory]Beta-3 adrenergic receptor [gi:461604]
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8
[SID103226142]
IC50 DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein) [AID625182, Type: confirmatory]Mitogen-activated protein kinase 14 [gi:2499600]
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9
[SID103226142]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) [AID625192, Type: confirmatory]5-hydroxytryptamine receptor 2A [gi:543727]
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10
[SID103226142]
IC50 DRUGMATRIX: Alpha-1B adrenergic receptor radioligand binding (ligand: prazosin) [AID625199, Type: confirmatory]Alpha-1B adrenergic receptor [gi:543734]
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11
[SID103226142]
IC50 DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA) [AID625195, Type: confirmatory]Adenosine receptor A2a [gi:543740]
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12
[SID103226142]
IC50 DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625155, Type: confirmatory]Muscarinic acetylcholine receptor M5 [gi:543761]
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13
[SID103226142]
IC50 DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) [AID625258, Type: confirmatory]Estrogen receptor [gi:544257]
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14
[SID103226142]
IC50 DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine) [AID625269, Type: confirmatory]Histamine H1 receptor [gi:547645]
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15
[SID103226142]
IC50 DRUGMATRIX: Vasopressin V1A radioligand binding (ligand: [125I] PhenylacetylTyr(Me)PheGlnAsnArgProArgTyr) [AID625233, Type: confirmatory]Vasopressin V1a receptor [gi:586197]
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16
[SID103226142]
IC50 DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH) [AID625149, Type: confirmatory]Melanocortin receptor 5 [gi:729996]
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17
[SID103226142]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide) [AID625217, Type: confirmatory]5-hydroxytryptamine receptor 2B [gi:1168220]
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18
[SID103226142]
IC50 DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) [AID625200, Type: confirmatory]Alpha-1D adrenergic receptor [gi:1168243]
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19
[SID103226142]
IC50 DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) [AID625198, Type: confirmatory]Alpha-1D adrenergic receptor [gi:1168244]
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20
[SID103226142]
IC50 DRUGMATRIX: Aldose Reductase enzyme inhibition (substrate: DL-Glyceraldehyde) [AID625208, Type: confirmatory]Aldose reductase [gi:1168407]
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