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DL-Cysteine (CID 594) - Compound BioActivity Data
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BioActivity Outcomes:
Active(22)
 
 
Inactive(152)
 
 
Inconclusive(49)
 
 
Unspecified(13)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD TR(5)
 
 
PLDc mTdp1 2(5)
 
 
 
BioAssay Types:
Confirmatory(121)
 
 
 
 
 
Literature(73)
 
 
 
 
 
Summary(24)
 
 
Screening(4)
 
 
 
BioActivity Types:
Potency(135)
 
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 161    Data Row: 236   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID29216046]
Potency 4.2562Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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2
[SID29216046]
Potency 15.8489qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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3
[SID29216046]
Potency 17.7828qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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4
[SID29216046]
Potency 44.6684Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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5
[SID14720397]
Compound Screen Assay, Human CENTG1 [AID511, Type: screening]arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform PIKE-A [Homo sapiens] [gi:7661962]
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6
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_52, Type: Literature]
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7
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_53, Type: Literature]
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8
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_54, Type: Literature]
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9
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_55, Type: Literature]
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10
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_57, Type: Literature]
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11
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_58, Type: Literature]
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12
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_3, Type: Literature]
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13
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_7, Type: Literature]
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14
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_8, Type: Literature]
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15
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_1, Type: Literature]
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16
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_13, Type: Literature]
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17
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_15, Type: Literature]
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18
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_19, Type: Literature]
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19
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_20, Type: Literature]
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20
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_21, Type: Literature]
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21
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_34, Type: Literature]
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22
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_39, Type: Literature]
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23
[SID29216046]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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24
[SID103241626]
Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assay [AID256510, Type: Literature]Disintegrin and metalloproteinase domain-containing protein 17 [gi:14423632]
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25
[SID124892250]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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26
[SID103241626]
Dissociation constant, pKa of the compound [AID637281, Type: Literature]
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27
[SID103241626]
Induction of increased cytosolic glutathione S-transferase activity in bladder of A/J mice treated with 3 doses of 0.04 mM compound (dissolved in 0.3 mL of cottonseed oil) for 2 days [AID75140, Type: Literature]
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28
[SID103241626]
Induction of increased cytosolic glutathione S-transferase activity in forestomach of A/J mice treated with 3 doses of 0.04 mM compound (dissolved in 0.3 mL of cottonseed oil) for 2 days [AID75142, Type: Literature]
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29
[SID103241626]
Induction of increased cytosolic glutathione S-transferase activity in large bowel mucosa of A/J mice treated with 3 doses of 0.04 mM compound (dissolved in 0.3 mL of cottonseed oil) for 2 days [AID75144, Type: Literature]
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30
[SID103241626]
Induction of increased cytosolic glutathione S-transferase activity in liver of A/J mice treated with 3 doses of 0.04 mM compound (dissolved in 0.3 mL of cottonseed oil) for 2 days [AID75146, Type: Literature]
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31
[SID103241626]
Induction of increased cytosolic glutathione S-transferase activity in lung of A/J mice treated with 3 doses of 0.04 mM compound (dissolved in 0.3 mL of cottonseed oil) for 2 days [AID75147, Type: Literature]
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32
[SID103241626]
Induction of increased cytosolic glutathione S-transferase activity in small bowel mucosa of A/J mice treated with 3 doses of 0.04 mM compound (dissolved in 0.3 mL of cottonseed oil) for 2 days [AID75149, Type: Literature]
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33
[SID103241626]
Ratio of glutathione S-transferase activity in tested (cottonseed oil alone + compound) to that of control (cottonseed oil alone) [AID232171, Type: Literature]
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34
[SID103241626]
Percentage of cleavage in single stranded peptide nucleic acid was measured after treating with compound for 10 min; selectivity factor=0.6; PNA:DNA=5a:6 [AID251091, Type: Literature]
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35
[SID103241626]
Percentage of cleavage in single stranded peptide nucleic acid (PNA) inverted question markDNA duplex was measured after treating with compound for 10 min; selectivity factor=0.6; PNA:DNA=5a:6 [AID251109, Type: Literature]
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36
[SID124892250]
Potency 3.1623qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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37
[SID124892250]
Potency 5.6234qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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38
[SID29216046]
Potency 40.5334Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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39
[SID124892250]
Potency 50.1187qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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40
[SID124892250]
Potency qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588456, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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41
[SID124892250]
qHTS for Agonists of the Human Mucolipin Transient Receptor Potential 1 (TRPML1) [AID624414, Type: screening]mucolipin-1 [Homo sapiens] [gi:10092597]
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42
[SID124892250]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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43
[SID29216046]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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44
[SID29216046]
Potency A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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45
[SID29216046]
Potency A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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46
[SID29216046]
Potency S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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47
[SID29216046]
Potency S16 Schwann cell PMP22 intronic element beta-lactamase assay [AID624044, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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48
[SID29216046]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
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49
[SID29216046]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide [AID1766, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
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50
[SID170464842]
Ratio Potency (uM) qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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