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CHEMBL66854 (CID 5897572) - Compound BioActivity Data
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BioActivity Outcomes:
Active(42)
 
 
Inactive(503)
 
 
Inconclusive(19)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(37)
 
 
Peptidase C48(8)
 
 
 
Esterase lipa..(6)
 
 
 
alkPPc(6)
 
 
 
CAP ED(5)
 
 
BioAssay Types:
Screening(386)
 
 
 
 
Confirmatory(159)
 
 
 
 
 
Literature(13)
 
 
 
BioActivity Types:
Potency(121)
 
 
 
 
 
IC50(30)
 
 
 
 
EC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 514    Data Row: 565   Total Pages: 29   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49646548]
Potency 0.3162qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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2
[SID49646548]
Potency 1.6944qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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3
[SID49646548]
Potency 2.8184qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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4
[SID49646548]
Potency 3.5481qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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5
[SID49646548]
Potency 11.2202qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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6
[SID49646548]
Potency 11.2202qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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7
[SID49646548]
Potency 13.1154Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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8
[SID103259533]
IC50 14Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transfer [AID91426, Type: Literature]Integrase [gi:82312013]
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9
[SID103259533]
IC50 23.9Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessing [AID91425, Type: Literature]Integrase [gi:82312013]
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10
[SID49646548]
EC50 24.614Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 [AID1960, Type: confirmatory]Zinc finger protein mex-5 [gi:55976631]
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11
[SID49646548]
Potency 31.6228qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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12
[SID49646548]
EC50 42.851Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA [AID1964, Type: confirmatory]Protein POS-1 [Caenorhabditis elegans] [gi:17562800]
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13
[SID49646548]
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 6 (SENP6) [AID2599, Type: screening]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
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14
[SID49646548]
Single concentration confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay [AID488915, Type: screening]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
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15
[SID49646548]
Counterscreen for activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM): Luminescence-based cell-based high throughput screening assay to identify non-selective compounds using the VP16 reporter assay [AID686939, Type: screening]
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16
[SID49646548]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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17
[SID49646548]
Confirmation assay for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID1053136, Type: screening]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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18
[SID49646548]
uHTS luminescence assay for the identification of chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation [AID435003, Type: screening]
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19
[SID49646548]
Luminescence-based counterscreen assay for HSP90 inhibitors: biochemical high throughput screening assay to identify inhibitors of native luciferase. [AID1847, Type: screening]
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20
[SID49646548]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
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