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NAD (CID 5892) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(72)
 
 
Inconclusive(28)
 
 
Unspecified(21)
 
 
Top Targets:
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
NR LBD GR(4)
 
 
NR LBD TR(3)
 
 
7TM GPCR Srsx(2)
 
 
BioAssay Types:
Confirmatory(52)
 
 
 
Summary(15)
 
 
 
Literature(10)
 
 
Screening(4)
 
 
BioActivity Types:
Potency(63)
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 120    Data Row: 121   Total Pages: 7   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID8149434]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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2
[SID8149434]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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3
[SID8149434]
Screen for compounds that induce the human heat shock transcriptional response (HSEluc) [AID1611, Type: other]
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4
[SID8149434]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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5
[SID8149434]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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6
[SID8149434]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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7
[SID8149434]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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8
[SID104250768]
Michaelis-Menten constant against mammalian liver alcohol dehydrogenase (ADH) [AID33708, Type: Literature]
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9
[SID104250768]
Compound was tested for inhibition of choline acetyltransferase isolated from squid head ganglia; No inhibition at 10e-4 M [AID52125, Type: Literature]
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10
[SID104250768]
Michaelis-Menten constant against mammalian glutamate dehydrogenase (GDH) [AID74666, Type: Literature]
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11
[SID104250768]
Inhibitory binding constant was determined against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II) from intercept of Michaelis-Menten plot [AID92753, Type: Literature]
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12
[SID104250768]
Inhibitory binding constant was determined against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II) from slope of Michaelis-Menten plot [AID92754, Type: Literature]
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13
[SID104250768]
Michaelis-Menten constant against mammalian lactate dehydrogenase (LDH) [AID99367, Type: Literature]
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14
[SID104250768]
Michaelis-Menten constant against mammalian malate dehydrogenase (MDH) [AID106795, Type: Literature]
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15
[SID104250768]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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16
[SID104250768]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature]
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17
[SID104250768]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature]
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18
[SID8149434]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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19
[SID8149434]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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20
[SID8149434]
Screening of compounds showing protective effect against cell death induced by familial amyotrophic lateral sclerosis (FALS)-linked mutantsuperoxide dismutase 1 (SOD1) (ALSOD1) [AID1605, Type: other]
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