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Isoproterenol (CID 5807) - Compound BioActivity Data
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BioActivity Outcomes:
Active(40)
 
 
Inactive(1079)
 
 
Inconclusive(101)
 
 
Unspecified(27)
 
 
Top Targets:
7TM GPCR Srsx(31)
 
 
 
NR LBD PPAR(26)
 
 
 
7TM GPCR Srx(24)
 
 
 
NR LBD TR(20)
 
 
NR LBD ER(19)
 
 
 
BioAssay Types:
Confirmatory(682)
 
 
 
 
 
Screening(392)
 
 
 
 
Summary(50)
 
 
 
 
Literature(39)
 
 
 
 
BioActivity Types:
Potency(638)
 
 
 
 
 
IC50(31)
 
 
 
EC50(9)
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 862    Data Row: 1247   Total Pages: 63   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID50085961]
Potency 0.0082qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation with GloSensor [AID588790, Type: confirmatory]beta-2 adrenergic receptor [Homo sapiens] [gi:4501969]
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2
[SID103676191]
EC50 0.12882Agonist activity at recombinant human beta2 adrenoceptor expressed in DU145 cells assessed as increase in cAMP accumulation [AID637886, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
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3
[SID50085961]
Potency 0.1836qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation [AID588463, Type: confirmatory]beta-2 adrenergic receptor [Homo sapiens] [gi:4501969]
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4
[SID103676191]
EC50 0.24Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]-cAMP after 30 mins by liquid scintillation counting [AID637823, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
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5
[SID17388957]
Potency 0.3981qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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6
[SID103676191]
Ki 0.501Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cells [AID637822, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
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7
[SID56320928]
EC50_MICROM 0.822Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]beta-2 adrenergic receptor [Homo sapiens] [gi:4501969]
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8
[SID56320927]
EC50_MICROM 0.828Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]beta-2 adrenergic receptor [Homo sapiens] [gi:4501969]
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9
[SID50085961]
Potency 7.0795qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]beta-2 adrenergic receptor [Homo sapiens] [gi:4501969]
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10
[SID103676191]
IC50 7.94328Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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11
[SID50085961]
Potency 11.2202qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia [AID2451, Type: confirmatory]Chain A, Structure Of Giardia Fructose-1,6-biphosphate Aldolase In Complex With Phosphoglycolohydroxamate [gi:122920737]
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12
[SID26747558]
Potency 14.1254qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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13
[SID50106483]
Potency 14.1254qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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14
[SID50106527]
Potency 15.8489qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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15
[SID144210628]
AhR Potency (uM) 61.1306qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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16
[SID144210628]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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17
[SID144210628]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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18
[SID50085961]
IC50 100High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media [AID449762, Type: confirmatory]
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19
[SID8149393]
Screen for compounds that suppress mutant SOD1-mediated cell death (mSODtox) [AID1601, Type: other]
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20
[SID8149393]
Cellular toxicity caused by inducible expressing of N-terminal huntingtin with expanded ployglutamine repeat (Htt-N63-148Q) in PC12 cells (ROSShtt) [AID1590, Type: other]
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