Isoproterenol (CID 5807) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(33)
 
 
Inactive(815)
 
 
Inconclusive(77)
 
 
Unspecified(18)
 
 
Top Targets:
7TM GPCR Srsx(20)
 
 
 
 
7TM GPCR Srx(17)
 
 
 
NR LBD TR(14)
 
 
HELICc(13)
 
 
 
NR LBD PPAR(10)
 
 
 
BioAssay Types:
Confirmatory(507)
 
 
 
 
 
Screening(335)
 
 
 
 
Literature(20)
 
 
 
 
Summary(2)
 
 
BioActivity Types:
Potency(431)
 
 
 
 
 
IC50(28)
 
 
 
EC50(8)
 
 
 
Ki(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 720    Data Row: 943   Total Pages: 19   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID50085961]
Potency 0.0082qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation with GloSensor [AID588790, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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2
[SID50085961]
Potency 0.0082qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation with GloSensor [AID588790, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
3
[SID50085961]
Potency 0.0082qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation with GloSensor [AID588790, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
4
[SID50085961]
Potency 0.0082qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation with GloSensor [AID588790, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
5
[SID50085961]
Potency 0.1836qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation [AID588463, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
6
[SID50085961]
Potency 0.1836qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation [AID588463, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
7
[SID50085961]
Potency 0.1836qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation [AID588463, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
8
[SID50085961]
Potency 0.1836qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation [AID588463, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
9
[SID103676191]
EC50 0.24Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]-cAMP after 30 mins by liquid scintillation counting [AID637823, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
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10
[SID103676191]
EC50 0.24Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]-cAMP after 30 mins by liquid scintillation counting [AID637823, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
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11
[SID103676191]
EC50 0.24Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]-cAMP after 30 mins by liquid scintillation counting [AID637823, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
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12
[SID103676191]
EC50 0.24Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]-cAMP after 30 mins by liquid scintillation counting [AID637823, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
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13
[SID17388957]
Potency 0.3981qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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14
[SID17388957]
Potency 0.3981qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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15
[SID17388957]
Potency 0.3981qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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16
[SID103676191]
Ki 0.501Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cells [AID637822, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
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17
[SID103676191]
Ki 0.501Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cells [AID637822, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
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18
[SID103676191]
Ki 0.501Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cells [AID637822, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
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19
[SID103676191]
Ki 0.501Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cells [AID637822, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
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20
[SID56320928]
EC50 0.822Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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21
[SID56320928]
EC50 0.822Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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22
[SID56320928]
EC50 0.822Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
23
[SID56320928]
EC50 0.822Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
24
[SID56320927]
EC50 0.828Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
25
[SID56320927]
EC50 0.828Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
26
[SID56320927]
EC50 0.828Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
27
[SID56320927]
EC50 0.828Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
28
[SID50085961]
Potency 7.0795qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
29
[SID50085961]
Potency 7.0795qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
30
[SID50085961]
Potency 7.0795qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
31
[SID50085961]
Potency 7.0795qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
32
[SID103676191]
IC50 7.94328Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
View
33
[SID50085961]
Potency 11.2202qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia [AID2451, Type: confirmatory]Chain A, Structure Of Giardia Fructose-1,6-Biphosphate Aldolase In Complex With Phosphoglycolohydrox [gi:122920737]
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34
[SID26747558]
Potency 14.1254qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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35
[SID50106483]
Potency 14.1254qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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36
[SID50106527]
Potency 15.8489qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
View
37
[SID50085961]
IC50 100High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media [AID449762, Type: confirmatory]
View
38
[SID8149393]
 Cellular toxicity caused by inducible expressing of N-terminal huntingtin with expanded ployglutamine repeat (Htt-N63-148Q) in PC12 cells (ROSShtt) [AID1590, Type: other]
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39
[SID8149393]
 Screen for compounds that suppress mutant SOD1-mediated cell death (mSODtox) [AID1601, Type: other]
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40
[SID50085961]
 Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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41
[SID56320927]
 Counterscreen for activators of kallikrein-7 (K7) zymogen: Fluorescence intensity-based biochemical high throughput counterscreen assay for activators that optically interfere with measurement of EDANS-DABCYL fluorescence [AID686952, Type: screening]
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42
[SID56320928]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
43
[SID56320928]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
44
[SID56320928]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
45
[SID56320928]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
46
[SID56463187]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
47
[SID56463187]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
48
[SID56463187]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
49
[SID56463187]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
50
[SID56320927]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View