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BioActivity Data for Compound DSSTox_CID_28699 (CID 57823090)

BioActivity Outcomes:
Active(4)
 
 
Inactive(103)
 
 
Inconclusive(11)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
 
NR LBD GR(4)
 
 
BioAssay Types:
Confirmatory(84)
 
 
 
 
 
Summary(29)
 
 
 
 
Screening(7)
 
 
BioAssay Categories:
Toxicity(6)
 
 
Cell-based(6)
 
 
BioActivity Types:
Potency(100)
 
 
 
 
AC50(6)
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 120    Data Row: 120   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144206799]
Ratio Potency (uM) 0.106822qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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2
[SID144206799]
Potency-Replicate_1 0.1199qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743094, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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3
[SID170466025]
Ratio Potency (uM) 11.0044qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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4
[SID170466025]
Potency-Replicate_1 11.8823qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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5
[SID170466025]
AC50 (uM) qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green channel [AID1117298, Type: confirmatory]
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6
[SID170466025]
AC50 (uM) qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio channel [AID1117305, Type: confirmatory]
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7
[SID144206799]
Potency-Replicate_1 7.5624qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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8
[SID144206799]
Potency-Replicate_1 30.1065qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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9
[SID170466025]
IC50 33.33insulin secretion from INS-1E cells in the presence of 5 mM glucose-IC50 [AID1117331, Type: confirmatory]
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10
[SID170466025]
AC50 (uM) 39.8107qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue channel [AID1117304, Type: confirmatory]
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11
[SID170466025]
Ac50 39.8107qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, blue channel [AID1117314, Type: confirmatory]
View
12
[SID170466025]
nuclear beta catenin stimulation in WNT3A conditioned C2C12 cells-screen [AID1117326, Type: screening]
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13
[SID170466025]
Antagonist Potency (uM) qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway: Summary [AID1159523, Type: summary]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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14
[SID170466025]
Ac50 qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
View
15
[SID170466025]
Ac50 qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
View
16
[SID170466025]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743226, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
17
[SID170466025]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743241, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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18
[SID170466025]
qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743242, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
19
[SID170466025]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway [AID743222, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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20
[SID144206799]
AhR Potency (uM) qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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