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8-methoxy-3-propan-2-ylsulfanyl-5H-[1,2,4]triazino[5,6-b]indole (CID 5770870) - Compound BioActivity Data
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BioActivity Outcomes:
Active(30)
 
 
Inactive(776)
 
 
Inconclusive(21)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(48)
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(548)
 
 
 
 
 
Confirmatory(250)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(170)
 
 
 
 
 
IC50(47)
 
 
 
EC50(11)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 760    Data Row: 829   Total Pages: 42   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID852113]
Potency 0.3381qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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2
[SID852113]
Potency 0.7079qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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3
[SID852113]
Potency 0.7943qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
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4
[SID852113]
Potency 1.5849qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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5
[SID852113]
Potency 2.2387qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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6
[SID852113]
Potency 5.2213Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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7
[SID852113]
Potency 10qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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8
[SID852113]
Potency 15.8489qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature [AID924, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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9
[SID852113]
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]transcription factor p65 isoform 1 [Homo sapiens] [gi:223468676]
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10
[SID852113]
Allosteric Modulators of D1 Receptors: Primary Screen [AID641, Type: screening]
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11
[SID852113]
Counter Screen for Luciferase-based Primary Inhibition Assays [AID1006, Type: screening]
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12
[SID852113]
Identification of compounds which are cytotoxic to PPC-1 cells. [AID1447, Type: screening]
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13
[SID852113]
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells [AID1443, Type: screening]tumor necrosis factor ligand superfamily member 10 isoform 1 [Homo sapiens] [gi:4507593]
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14
[SID852113]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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15
[SID852113]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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16
[SID852113]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the DAF-12 from the parasite H. contortus (hcDAF-12) [AID652067, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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17
[SID852113]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) [AID652126, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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18
[SID852113]
Luminescence-based cell-based primary high throughput screening assay to identify agonists of the DAF-12 from the parasite H. glycines (hgDAF-12). [AID687014, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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19
[SID852113]
Luminescence-based cell-based high throughput confirmation assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12) [AID743032, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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20
[SID852113]
EC50 Luminescent HTS for small molecule inhibitors of MT1-MMP transcription [AID618, Type: confirmatory]matrix metalloproteinase 1, partial [Homo sapiens] [gi:6690534]
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