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Reserpine (CID 5770) - Compound BioActivity Data
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BioActivity Outcomes:
Active(263)
 
 
Inactive(886)
 
 
Inconclusive(392)
 
 
Unspecified(396)
 
 
Top Targets:
7TM GPCR Srx(43)
 
 
 
 
 
ABC MTABC3 MD..(35)
 
 
 
NR LBD PPAR(34)
 
 
 
MFS(33)
 
 
 
 
7TM GPCR Srsx(33)
 
 
 
BioAssay Types:
Confirmatory(839)
 
 
 
 
 
Literature(414)
 
 
 
 
 
Screening(337)
 
 
 
 
Summary(73)
 
 
 
 
BioActivity Types:
Potency(675)
 
 
 
 
 
IC50(173)
 
 
 
 
 
Ki(10)
 
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1351    Data Row: 1937   Total Pages: 97   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103204244]
Ki 0.001Inhibition of dopamine uptake at VMAT in bovine chromaffin granule ghosts [AID321546, Type: Literature]Synaptic vesicular amine transporter [gi:2499124]
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2
[SID103204244]
Ki 0.1Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affinity model [AID150616, Type: Literature]
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3
[SID50105550]
Potency 0.2818qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 7G8 [AID1815, Type: confirmatory]
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4
[SID103204244]
IC50 0.31623Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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5
[SID103204244]
IC50 0.774DRUGMATRIX: Sodium Channel, Site 2 radioligand binding (ligand: [3H] Batrachotoxin) [AID625225, Type: confirmatory]
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6
[SID50105550]
Potency 0.7943qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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7
[SID50105550]
Potency 0.7943qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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8
[SID103204244]
IC50 0.79433Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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9
[SID103204244]
IC50 0.821DRUGMATRIX: Calcium Channel Type L, Dihydropyridine radioligand binding (ligand: [3H] Nitrendipine) [AID625216, Type: confirmatory]
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10
[SID144204658]
Potency-Replicate_1 0.8477qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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11
[SID50105550]
Potency 0.8913qHTS for differential inhibitors of proliferation of Plasmodium falciparum line W2 [AID1883, Type: confirmatory]
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12
[SID50105550]
Potency 0.9285Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID488745, Type: confirmatory]
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13
[SID144204658]
Ratio Potency (uM) 1.19739qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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14
[SID50105550]
Potency 1.2589qHTS for differential inhibitors of proliferation of Plasmodium falciparum line HB3 [AID1886, Type: confirmatory]
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15
[SID103204244]
IC50 1.25893Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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16
[SID56463068]
Potency 1.4716Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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17
[SID50105550]
Potency 1.4716Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID488752, Type: confirmatory]
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18
[SID103204244]
IC50 1.6Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex [AID205267, Type: Literature]
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19
[SID56463068]
Potency 1.6511Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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20
[SID50105550]
Potency 1.7783qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 3D7 [AID1876, Type: confirmatory]
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