Bookmark and Share
Corticosterone (CID 5753) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(40)
 
 
Inactive(1394)
 
 
Inconclusive(147)
 
 
Unspecified(112)
 
 
Top Targets:
NR LBD PPAR(40)
 
 
 
7TM GPCR Srx(31)
 
 
NR LBD ER(29)
 
 
 
7TM GPCR Srsx(25)
 
 
NR LBD AR(25)
 
 
 
 
BioAssay Types:
Confirmatory(731)
 
 
 
 
 
Screening(629)
 
 
 
 
Literature(162)
 
 
 
 
 
Summary(72)
 
 
 
 
BioActivity Types:
Potency(673)
 
 
 
 
 
IC50(58)
 
 
 
 
Ki(11)
 
 
 
EC50(11)
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1226    Data Row: 1693   Total Pages: 34   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144208564]
Potency-Replicate_1 0.0693qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway [AID720691, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
2
[SID144208564]
Ratio Potency (uM) 0.0840024qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720719, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
3
[SID144213947]
Potency-Replicate_1 0.1087qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
4
[SID144208564]
Potency-Replicate_1 0.1222qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
5
[SID144213947]
Potency-Replicate_1 0.123qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway [AID720691, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
6
[SID144213947]
Ratio Potency (uM) 0.138022qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720719, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
7
[SID144204430]
Potency-Replicate_1 0.1693qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway [AID720691, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
8
[SID26751495]
Potency 0.2239qHTS assay for small molecule agonists of androgen receptor signaling [AID588515, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
9
[SID144213947]
Potency-Replicate_1 0.2454qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
10
[SID144204430]
Ratio Potency (uM) 0.262134qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720719, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
11
[SID144213947]
Ratio Potency (uM) 0.291709qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
12
[SID144208564]
Ratio Potency (uM) 0.311869qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
13
[SID17389502]
Potency 0.3162qHTS assay for small molecule agonists of androgen receptor signaling [AID588515, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
14
[SID144204430]
Potency-Replicate_1 0.3758qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
15
[SID56423132]
Potency 0.4109Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
16
[SID144208564]
Potency-Replicate_1 0.4375qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
17
[SID103333099]
Kd 0.45709Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin [AID318680, Type: Literature]Sex hormone-binding globulin [gi:134907]
View
18
[SID144204430]
Potency-Replicate_1 0.6007qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
19
[SID144204430]
Potency-Replicate_1 0.6007qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway [AID743036, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
20
[SID144204430]
Ratio Potency (uM) 0.881713qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
21
[SID56423132]
Potency 1.2995Nrf2 qHTS screen for inhibitors: Nrf2 A549 ARE-Fluc Confirmation Assay for Hit Validation [AID720524, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
22
[SID90341091]
Potency 6.5131Nrf2 qHTS screen for inhibitors: Validation [AID493153, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
23
[SID90341091]
Potency 6.5131Nrf2 qHTS screen for inhibitors: Validation [AID493153, Type: confirmatory] [geneid:4780]
View
24
[SID103333099]
IC50 10Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
View
25
[SID103333099]
IC50 10Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
View
26
[SID103333099]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
View
27
[SID144213947]
TR Potency (uM) 19.3312qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
28
[SID103333099]
IC50 23.4423Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881) [AID255211, Type: Literature]
View
29
[SID103333099]
Ki 35.6Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand [AID239347, Type: Literature]
View
30
[SID144213947]
Potency-Replicate_1 38.5708qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
31
[SID144213947]
Potency-Replicate_1 43.2771qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
32
[SID144208564]
Potency-Replicate_1 48.6565qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
33
[SID144208564]
Potency-Replicate_1 61.2549qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
34
[SID144208564]
Ratio Potency (uM) 68.7291qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
View
35
[SID56423132]
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity [AID504775, Type: screening]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
View
36
[SID855741]
GR-GFP Redistribution [AID450, Type: confirmatory]glucocorticoid receptor isoform gamma [Homo sapiens] [gi:66528677]
View
37
[SID855741]
IC50 uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) [AID2012, Type: confirmatory]Eukaryotic translation initiation factor 4H [Homo sapiens] [gi:45219878]
View
38
[SID144208564]
qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720725, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
39
[SID144213947]
qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720725, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
40
[SID144204430]
qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720725, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
41
[SID103333099]
IC50 0.29TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 0.25 uM) in OCT3-expressing HEK293 cells [AID682144, Type: other]Solute carrier family 22 member 3 [gi:24212063]
View
42
[SID103333099]
Ki 0.39TP_TRANSPORTER: inhibition of Dopamine uptake in OCT2-expressing HEK293 cells [AID679639, Type: other]Solute carrier family 22 member 2 [gi:81872789]
View
43
[SID103333099]
Ki 0.42TP_TRANSPORTER: inhibition of Adrenaline uptake in OCT2-expressing HEK293 cells [AID679641, Type: other]Solute carrier family 22 member 2 [gi:81872789]
View
44
[SID103333099]
Ki 0.46TP_TRANSPORTER: inhibition of Noradrenaline uptake in OCT2-expressing HEK293 cells [AID679637, Type: other]Solute carrier family 22 member 2 [gi:81872789]
View
45
[SID103333099]
Ki 0.605TP_TRANSPORTER: inhibition of Serotonin uptake in OCT2-expressing HEK293 cells [AID679636, Type: other]Solute carrier family 22 member 2 [gi:81872789]
View
46
[SID103333099]
IC50 4TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytes [AID681158, Type: other]Solute carrier family 22 member 2 [gi:81872789]
View
47
[SID103333099]
IC50 4.2TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM) in OCT2-expressing HRPE cells [AID681591, Type: other]Solute carrier family 22 member 2 [gi:81872789]
View
48
[SID103333099]
IC50 4.9TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM) in OCT3-expressing HRPE cells [AID678784, Type: other]Solute carrier family 22 member 3 [gi:24212062]
View
49
[SID103333099]
Ki 5.3TP_TRANSPORTER: inhibition of E217betaG uptake in Oatp1-expressing HeLa cells [AID681147, Type: other]Solute carrier organic anion transporter family member 1A1 [gi:1171883]
View
50
[SID103333099]
Ki 7.02TP_TRANSPORTER: inhibition of TEA uptake in OCT1-expressing HeLa cells [AID681146, Type: other]Solute carrier family 22 member 1 [gi:313104181]
View