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Mitomycin (CID 5746) - Compound BioActivity Data
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BioActivity Outcomes:
Active(926)
 
 
Inactive(534)
 
 
Inconclusive(64)
 
 
Unspecified(600)
 
 
Top Targets:
7TM GPCR Srx(36)
 
 
 
7TM GPCR Srsx(32)
 
 
 
p450(16)
 
 
 
 
NR LBD ER(9)
 
 
 
 
 
NR LBD AR(8)
 
 
 
 
 
BioAssay Types:
Literature(598)
 
 
 
 
 
Screening(336)
 
 
 
 
Confirmatory(258)
 
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
IC50(891)
 
 
 
 
 
Potency(188)
 
 
 
 
 
EC50(16)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2078    Data Row: 2124   Total Pages: 43   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176321]
IC50 2.21e-05SANGER: Inhibition of human NTERA-S-cl-D1 cell growth in a cell viability assay. [AID741784, Type: other]
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2
[SID103176321]
IC50 3.25e-05SANGER: Inhibition of human MOLT-4 cell growth in a cell viability assay. [AID742374, Type: other]
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3
[SID103176321]
IC50 0.000119SANGER: Inhibition of human J82 cell growth in a cell viability assay. [AID742254, Type: other]
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4
[SID103176321]
IC50 0.000128SANGER: Inhibition of human 697 cell growth in a cell viability assay. [AID741935, Type: other]
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5
[SID103176321]
IC50 0.000149SANGER: Inhibition of human KYSE-510 cell growth in a cell viability assay. [AID742296, Type: other]
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6
[SID103176321]
IC50 0.000151SANGER: Inhibition of human NCI-H2170 cell growth in a cell viability assay. [AID741731, Type: other]
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7
[SID103176321]
IC50 0.000167SANGER: Inhibition of human BE-13 cell growth in a cell viability assay. [AID741975, Type: other]
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8
[SID103176321]
IC50 0.000249SANGER: Inhibition of human LC-2-ad cell growth in a cell viability assay. [AID742313, Type: other]
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9
[SID103176321]
IC50 0.000308SANGER: Inhibition of human IMR-5 cell growth in a cell viability assay. [AID742247, Type: other]
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10
[SID103176321]
IC50 0.00031SANGER: Inhibition of human EW-16 cell growth in a cell viability assay. [AID742160, Type: other]
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11
[SID103176321]
IC50 0.000638SANGER: Inhibition of human MC-IXC cell growth in a cell viability assay. [AID742338, Type: other]
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12
[SID103176321]
IC50 0.000676SANGER: Inhibition of human SW872 cell growth in a cell viability assay. [AID741914, Type: other]
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13
[SID103176321]
IC50 0.000796SANGER: Inhibition of human NCI-H2228 cell growth in a cell viability assay. [AID741735, Type: other]
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14
[SID103176321]
ED50 0.001Compound is measured for surviving fractions of EMT6 tumor cells treated in culture with (0.50 uM) concentration for 1 hr under hypoxic condition. [AID67635, Type: Literature]
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15
[SID103176321]
IC50 0.001In vitro inhibitory activity against K562 leukemia cells [AID94811, Type: Literature]
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16
[SID103176321]
IC50 0.00107SANGER: Inhibition of human NALM-6 cell growth in a cell viability assay. [AID742386, Type: other]
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17
[SID103176321]
IC50 0.00108Inhibitory activity of compound for AA8 cells to reduce cell density by 50% (exposed to compound for 4 hours) [AID45745, Type: Literature]
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18
[SID103176321]
IC50 0.00156SANGER: Inhibition of human ES4 cell growth in a cell viability assay. [AID742148, Type: other]
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19
[SID103176321]
IC50 0.00164SANGER: Inhibition of human KE-37 cell growth in a cell viability assay. [AID742268, Type: other]
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20
[SID103176321]
IC50 0.00168SANGER: Inhibition of human IST-MEL1 cell growth in a cell viability assay. [AID742249, Type: other]
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21
[SID103176321]
IC50 0.00171SANGER: Inhibition of human ES8 cell growth in a cell viability assay. [AID742152, Type: other]
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22
[SID103176321]
IC50 0.00173SANGER: Inhibition of human MV-4-11 cell growth in a cell viability assay. [AID742380, Type: other]
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23
[SID103176321]
IC50 0.00176SANGER: Inhibition of human 639-V cell growth in a cell viability assay. [AID741933, Type: other]
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24
[SID103176321]
IC50 0.00189SANGER: Inhibition of human OCI-AML2 cell growth in a cell viability assay. [AID741790, Type: other]
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25
[SID103176321]
IC50 0.00222SANGER: Inhibition of human SK-LU-1 cell growth in a cell viability assay. [AID741865, Type: other]
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26
[SID103176321]
IC50 0.00255SANGER: Inhibition of human PSN1 cell growth in a cell viability assay. [AID741814, Type: other]
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27
[SID103176321]
IC50 0.00255SANGER: Inhibition of human REH cell growth in a cell viability assay. [AID741819, Type: other]
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28
[SID103176321]
IC50 0.00259SANGER: Inhibition of human SBC-5 cell growth in a cell viability assay. [AID741844, Type: other]
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29
[SID103176321]
IC50 0.00293SANGER: Inhibition of human HT-3 cell growth in a cell viability assay. [AID742232, Type: other]
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30
[SID103176321]
IC50 0.00352SANGER: Inhibition of human SIG-M5 cell growth in a cell viability assay. [AID741858, Type: other]
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31
[SID103176321]
IC50 0.00365SANGER: Inhibition of human ES7 cell growth in a cell viability assay. [AID742151, Type: other]
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32
[SID103176321]
IC50 0.00437SANGER: Inhibition of human CHP-212 cell growth in a cell viability assay. [AID742065, Type: other]
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33
[SID103176321]
IC50 0.00479SANGER: Inhibition of human P12-ICHIKAWA cell growth in a cell viability assay. [AID741802, Type: other]
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34
[SID103176321]
IC50 0.00483SANGER: Inhibition of human HUTU-80 cell growth in a cell viability assay. [AID742235, Type: other]
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35
[SID103176321]
IC50 0.00484SANGER: Inhibition of human P30-OHK cell growth in a cell viability assay. [AID741803, Type: other]
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36
[SID103176321]
IC50 0.00499SANGER: Inhibition of human NCI-H1651 cell growth in a cell viability assay. [AID741704, Type: other]
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37
[SID103176321]
IC50 0.005Cytotoxicity against BRCA2-deficient Chinese hamster V-C8 mutant cells after 3 days by WST1 cell viability assay [AID405950, Type: Literature]
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38
[SID103176321]
IC50 0.00554SANGER: Inhibition of human COR-L279 cell growth in a cell viability assay. [AID742081, Type: other]
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39
[SID103176321]
IC50 0.00583SANGER: Inhibition of human CMK cell growth in a cell viability assay. [AID742066, Type: other]
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40
[SID103176321]
IC50 0.00606SANGER: Inhibition of human MHH-CALL-2 cell growth in a cell viability assay. [AID742359, Type: other]
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41
[SID103176321]
IC50 0.00607SANGER: Inhibition of human BV-173 cell growth in a cell viability assay. [AID741988, Type: other]
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42
[SID103176321]
IC50 0.00617SANGER: Inhibition of human NCI-H209 cell growth in a cell viability assay. [AID741726, Type: other]
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43
[SID103176321]
IC50 0.00645SANGER: Inhibition of human NCI-H460 cell growth in a cell viability assay. [AID741752, Type: other]
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44
[SID103176321]
IC50 0.00652SANGER: Inhibition of human DU-145 cell growth in a cell viability assay. [AID742124, Type: other]
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45
[SID103176321]
IC50 0.007In vitro inhibition of SW480 colon cancer cell line [AID202213, Type: Literature]
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46
[SID103176321]
IC50 0.00711SANGER: Inhibition of human 769-P cell growth in a cell viability assay. [AID741936, Type: other]
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47
[SID103176321]
IC50 0.00729SANGER: Inhibition of human ES1 cell growth in a cell viability assay. [AID742146, Type: other]
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48
[SID103176321]
IC50 0.00755SANGER: Inhibition of human COLO-668 cell growth in a cell viability assay. [AID742069, Type: other]
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49
[SID103176321]
IC50 0.00783SANGER: Inhibition of human NKM-1 cell growth in a cell viability assay. [AID741780, Type: other]
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50
[SID103176321]
IC50 0.00788SANGER: Inhibition of human ES3 cell growth in a cell viability assay. [AID742147, Type: other]
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