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CHEMBL1957982 (CID 57398410) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Unspecified(1)
 
 
Top Targets:
Lipoxygenase(2)
 
 
 
BioAssay Types:
Literature(2)
 
 
 
BioActivity Types:
IC50(2)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2    Data Row: 2   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136936038]
IC50 0.5Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as reduction in A23187 and AA-stimulated 5-LO product formation preincubated for 15 mins prior stimulation measured after 10 mins by HPLC analysis [AID650762, Type: Literature]Arachidonate 5-lipoxygenase [gi:126407]
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2
[SID136936038]
IC50 10Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincubated for 15 mins measured after 10 mins by HPLC analysis [AID650763, Type: Literature]Arachidonate 5-lipoxygenase [gi:126407]
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