CHEMBL1908392 (CID 57397989) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(257)
 
 
Unspecified(185)
 
 
Top Targets:
PKc(55)
 
 
 
PKc like(34)
 
 
 
STKc AGC(24)
 
 
 
PTKc Abl(16)
 
 
PTKc EGFR(12)
 
 
BioAssay Types:
Literature(442)
 
 
 
BioActivity Types:
Kd(442)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 442    Data Row: 442   Total Pages: 9   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136935277]
Kd 0.00042Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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2
[SID136935277]
Kd 0.00042Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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3
[SID136935277]
Kd 0.00042Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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4
[SID136935277]
Kd 0.0007Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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5
[SID136935277]
Kd 0.0007Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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6
[SID136935277]
Kd 0.0007Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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7
[SID136935277]
Kd 0.00071Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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8
[SID136935277]
Kd 0.00071Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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9
[SID136935277]
Kd 0.00071Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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10
[SID136935277]
Kd 0.0018Binding constant for MEK5 kinase domain [AID624721, Type: Literature]Dual specificity mitogen-activated protein kinase kinase 5 [gi:118572669]
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11
[SID136935277]
Kd 0.0022Binding constant for BIKE kinase domain [AID625109, Type: Literature]BMP-2-inducible protein kinase [gi:34222653]
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12
[SID136935277]
Kd 0.0022Binding constant for BIKE kinase domain [AID625109, Type: Literature]BMP-2-inducible protein kinase [gi:34222653]
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13
[SID136935277]
Kd 0.0026Binding constant for FLT3(N841I) kinase domain [AID624939, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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14
[SID136935277]
Kd 0.0026Binding constant for FLT3(N841I) kinase domain [AID624939, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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15
[SID136935277]
Kd 0.0026Binding constant for FLT3(N841I) kinase domain [AID624939, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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16
[SID136935277]
Kd 0.0027Binding constant for KIT(L576P) kinase domain [AID624790, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
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17
[SID136935277]
Kd 0.0027Binding constant for KIT(L576P) kinase domain [AID624790, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
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18
[SID136935277]
Kd 0.0029Binding constant for KIT(V559D,T670I) kinase domain [AID624792, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
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19
[SID136935277]
Kd 0.0029Binding constant for KIT(V559D,T670I) kinase domain [AID624792, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
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20
[SID136935277]
Kd 0.0029Binding constant for VEGFR2 kinase domain [AID624860, Type: Literature]Vascular endothelial growth factor receptor 2 [gi:9087218]
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21
[SID136935277]
Kd 0.0029Binding constant for VEGFR2 kinase domain [AID624860, Type: Literature]Vascular endothelial growth factor receptor 2 [gi:9087218]
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22
[SID136935277]
Kd 0.0036Binding constant for PKNB(M.tuberculosis) kinase domain [AID624753, Type: Literature]Serine/threonine-protein kinase Pkn [gi:61229902]
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23
[SID136935277]
Kd 0.0038Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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24
[SID136935277]
Kd 0.0038Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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25
[SID136935277]
Kd 0.0038Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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26
[SID136935277]
Kd 0.0041Binding constant for TAK1 kinase domain [AID624724, Type: Literature]Mitogen-activated protein kinase kinase kinase 7 [gi:12643557]
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27
[SID136935277]
Kd 0.0041Binding constant for TAK1 kinase domain [AID624724, Type: Literature]Mitogen-activated protein kinase kinase kinase 7 [gi:12643557]
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28
[SID136935277]
Kd 0.0045Binding constant for TRKA kinase domain [AID624808, Type: Literature]High affinity nerve growth factor receptor [gi:94730402]
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29
[SID136935277]
Kd 0.0045Binding constant for TRKA kinase domain [AID624808, Type: Literature]High affinity nerve growth factor receptor [gi:94730402]
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30
[SID136935277]
Kd 0.0045Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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31
[SID136935277]
Kd 0.0045Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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32
[SID136935277]
Kd 0.0045Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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33
[SID136935277]
Kd 0.0048Binding constant for JAK1(JH2domain-pseudokinase) kinase domain [AID624858, Type: Literature]Tyrosine-protein kinase JAK1 [gi:215274013]
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34
[SID136935277]
Kd 0.0048Binding constant for JAK1(JH2domain-pseudokinase) kinase domain [AID624858, Type: Literature]Tyrosine-protein kinase JAK1 [gi:215274013]
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35
[SID136935277]
Kd 0.0049Binding constant for MELK kinase domain [AID625087, Type: Literature]Maternal embryonic leucine zipper kinase [gi:50400857]
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36
[SID136935277]
Kd 0.0049Binding constant for MELK kinase domain [AID625087, Type: Literature]Maternal embryonic leucine zipper kinase [gi:50400857]
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37
[SID136935277]
Kd 0.0052Binding constant for YSK4 kinase domain [AID625136, Type: Literature]Mitogen-activated protein kinase kinase kinase 19 [gi:74755104]
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38
[SID136935277]
Kd 0.0057Binding constant for KIT kinase domain [AID624786, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
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39
[SID136935277]
Kd 0.0057Binding constant for KIT kinase domain [AID624786, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
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40
[SID136935277]
Kd 0.0062Binding constant for LCK kinase domain [AID625013, Type: Literature]Tyrosine-protein kinase Lck [gi:125474]
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41
[SID136935277]
Kd 0.0062Binding constant for LCK kinase domain [AID625013, Type: Literature]Tyrosine-protein kinase Lck [gi:125474]
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42
[SID136935277]
Kd 0.0063Binding constant for KIT(V559D) kinase domain [AID624791, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
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43
[SID136935277]
Kd 0.0063Binding constant for KIT(V559D) kinase domain [AID624791, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
44
[SID136935277]
Kd 0.0082Binding constant for JAK3(JH1domain-catalytic) kinase domain [AID624785, Type: Literature]Tyrosine-protein kinase JAK3 [gi:50403745]
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45
[SID136935277]
Kd 0.0082Binding constant for JAK3(JH1domain-catalytic) kinase domain [AID624785, Type: Literature]Tyrosine-protein kinase JAK3 [gi:50403745]
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46
[SID136935277]
Kd 0.0084Binding constant for PRP4 kinase domain [AID624750, Type: Literature]Serine/threonine-protein kinase PRP4 homolog [gi:317373526]
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47
[SID136935277]
Kd 0.0085Binding constant for MERTK kinase domain [AID624767, Type: Literature]Tyrosine-protein kinase Mer [gi:160332297]
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48
[SID136935277]
Kd 0.0085Binding constant for MERTK kinase domain [AID624767, Type: Literature]Tyrosine-protein kinase Mer [gi:160332297]
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49
[SID136935277]
Kd 0.0088Binding constant for CLK1 kinase domain [AID624764, Type: Literature]Dual specificity protein kinase CLK1 [gi:206729857]
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50
[SID136935277]
Kd 0.0088Binding constant for CLK1 kinase domain [AID624764, Type: Literature]Dual specificity protein kinase CLK1 [gi:206729857]
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