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CHEMBL1689604 (CID 57397140) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(2)
 
 
Unspecified(1)
 
 
BioAssay Types:
Literature(3)
 
 
 
BioActivity Types:
IC50(3)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 3    Data Row: 3   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124968425]
IC50 18.72Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 infected in human red blood cells assessed as inhibition of ring-stage parasite growth after 48 hrs by flow cytometry [AID587703, Type: Literature]
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2
[SID124968425]
IC50 44.1Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence spectrophotometry [AID587701, Type: Literature]Falcipain 2 [gi:74944448]
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3
[SID124968425]
IC50 50Inhibition of Plasmodium falciparum falcipain 3 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence spectrophotometry [AID587702, Type: Literature]Cysteine protease falcipain-3 [gi:74944450]
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