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CHEMBL1935495 (CID 57397009) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(4)
 
 
 
BioAssay Types:
Literature(6)
 
 
 
BioActivity Types:
EC50(2)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136933272]
EC50 0.16Transactivation of human full length PPARgamma expressed in COS1 cells co-transfected with RXRalpha after 24 hrs by luciferase reporter gene assay [AID637345, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
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2
[SID136933272]
EC50 0.24Transactivation of human full length PPARalpha expressed in COS1 cells co-transfected with RXRalpha after 24 hrs by luciferase reporter gene assay [AID637346, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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3
[SID136933272]
IC50 2Inhibition of PTB1B using pNPP as substrate after 30 mins [AID637349, Type: Literature]
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4
[SID136933272]
Hypoglycemic activity in diabetic KK-Ay mouse model assessed as decrease in glucose level at 10 mg/kg, po qd for 4 days relative to untreated control [AID637350, Type: Literature]
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5
[SID136933272]
Transactivation of human full length PPARalpha expressed in COS1 cells co-transfected with RXRalpha after 24 hrs by luciferase reporter gene assay relative to WY14643 [AID637348, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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6
[SID136933272]
Transactivation of human full length PPARgamma expressed in COS1 cells co-transfected with RXRalpha after 24 hrs by luciferase reporter gene assay relative to farglitazar [AID637347, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
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