CHEMBL1951702 (CID 57391716) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(4)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(3)
 
 
BioAssay Types:
Literature(6)
 
 
 
BioActivity Types:
Ki(3)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136923502]
Ki 0.0046Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation counting [AID647794, Type: Literature]Mu-type opioid receptor [gi:2851402]
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2
[SID136923502]
Ki 0.0046Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation counting [AID647794, Type: Literature]Mu-type opioid receptor [gi:2851402]
View
3
[SID136923502]
Ki 0.0046Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation counting [AID647794, Type: Literature]Mu-type opioid receptor [gi:2851402]
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4
[SID136923502]
Ki 0.0046Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation counting [AID647794, Type: Literature]Mu-type opioid receptor [gi:2851402]
View
5
[SID136923502]
Ki 0.604Displacement of [3H]-U69593 from human kappa opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation counting [AID647796, Type: Literature]Kappa-type opioid receptor [gi:116242691]
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6
[SID136923502]
Ki 0.604Displacement of [3H]-U69593 from human kappa opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation counting [AID647796, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
7
[SID136923502]
Ki 0.604Displacement of [3H]-U69593 from human kappa opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation counting [AID647796, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
8
[SID136923502]
Ki 0.604Displacement of [3H]-U69593 from human kappa opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation counting [AID647796, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
9
[SID136923502]
Ki 1Displacement of [3H]-DADLE from human delta opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation counting [AID647795, Type: Literature]Delta-type opioid receptor [gi:311033488]
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10
[SID136923502]
Ki 1Displacement of [3H]-DADLE from human delta opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation counting [AID647795, Type: Literature]Delta-type opioid receptor [gi:311033488]
View
11
[SID136923502]
ED50 Antagonist activity at human mu receptor expressed in CHO cells membrane assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 3 hrs by liquid scintillation counting [AID647797, Type: Literature]Mu-type opioid receptor [gi:2851402]
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12
[SID136923502]
ED50 Antagonist activity at human mu receptor expressed in CHO cells membrane assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 3 hrs by liquid scintillation counting [AID647797, Type: Literature]Mu-type opioid receptor [gi:2851402]
View
13
[SID136923502]
ED50 Antagonist activity at human mu receptor expressed in CHO cells membrane assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 3 hrs by liquid scintillation counting [AID647797, Type: Literature]Mu-type opioid receptor [gi:2851402]
View
14
[SID136923502]
ED50 Antagonist activity at human mu receptor expressed in CHO cells membrane assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 3 hrs by liquid scintillation counting [AID647797, Type: Literature]Mu-type opioid receptor [gi:2851402]
View
15
[SID136923502]
 Selectivity ratio of Ki for human kappa opioid receptor to Ki for human mu opioid receptor [AID647798, Type: Literature]
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16
[SID136923502]
 Selectivity ratio of Ki for human delta opioid receptor to Ki for human mu opioid receptor [AID647799, Type: Literature]
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