CHEMBL1957878
(CID
5716998
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
1
)
Unspecified(2)
Top Targets:
prostaglandin..(
2
)
BioAssay Types:
Literature(
3
)
BioActivity Types:
IC50(
2
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 3 Data Row: 3 Total Pages: 1
Sort:
[Click the result table header to sort]
#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
136945557
]
Active
IC50
30.4
Inhibition of human recombinant COX-2 by enzyme immuno assay [AID
649270
, Type: Literature]
Prostaglandin G/H synthase 2 [gi:
3915797
]
View
X
Row No.
1
Structure
Substance
SID
136945557
CID
5716998
Outcome
Active
IC50
30.4 [uM]
BioAssay
Inhibition of human recombinant COX-2 by enzyme immuno assay
AID
649270
BioAssay type
Literature
Target
Prostaglandin G/H synthase 2 [gi:
3915797
]
PubMed
22361134
Data Table
2
[SID
136945557
]
Unspecified
IC50
62.3
Inhibition of ovine COX-1 by enzyme immuno assay [AID
649269
, Type: Literature]
Prostaglandin G/H synthase 1 [gi:
548481
]
View
X
Row No.
2
Structure
Substance
SID
136945557
CID
5716998
Outcome
Unspecified
IC50
62.3 [uM]
BioAssay
Inhibition of ovine COX-1 by enzyme immuno assay
AID
649269
BioAssay type
Literature
Target
Prostaglandin G/H synthase 1 [gi:
548481
]
PubMed
22361134
Data Table
3
[SID
136945557
]
Unspecified
Selectivity index, ratio of IC50 for ovine COX-1 to IC50 for human recombinant COX-2 [AID
649271
, Type: Literature]
View
X
Row No.
3
Structure
Substance
SID
136945557
CID
5716998
Outcome
Unspecified
BioAssay
Selectivity index, ratio of IC50 for ovine COX-1 to IC50 for human recombinant COX-2
AID
649271
BioAssay type
Literature
Target
PubMed
22361134
Data Table
Chemical Probe 
Active 
Inactive 
Inconclusive 
Unspecified 
