AC1NWZEM (CID 5716367) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Probe(1)
 
 
Active(45)
 
 
Inactive(124)
 
 
Inconclusive(4)
 
 
Top Targets:
7TM GPCR Srx(10)
 
 
 
7TM GPCR Srsx(4)
 
 
 
Nuc rec co-ac..(4)
 
 
Alpha TIF(4)
 
 
NR LBD Lrh-1(2)
 
 
BioAssay Types:
Screening(139)
 
 
 
 
Confirmatory(26)
 
 
 
 
Literature(3)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(24)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 174    Data Row: 174   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26543390]
 Summary of probe development efforts to identify inhibitors of Toll-Like Receptor 4 (TLR4). [AID1953, Type: summary]toll-like receptor 4 [Homo sapiens] [gi:55662034]
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2
[SID99495574]
Potency 0.0517qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID99495574]
Potency 0.0517qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID99495574]
Potency 0.0517qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID99495574]
Potency 0.058qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID99495574]
Potency 0.058qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID99495574]
Potency 0.058qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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8
[SID99495574]
Potency 1.1582qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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9
[SID99495574]
Potency 7.3078qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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10
[SID99495574]
Potency 7.3078qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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11
[SID99495574]
Potency 7.3078qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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12
[SID99495574]
Potency 7.9433qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ATXN2 gene product [Homo sapiens] [gi:171543895]
View
13
[SID99495574]
 Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2) [AID686940, Type: screening]NR2F2 gene product [Homo sapiens] [gi:14149746]
View
14
[SID99495574]
 Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2) [AID686940, Type: screening]NR2F2 gene product [Homo sapiens] [gi:14149746]
View
15
[SID99495574]
 qHTS for Agonists of the Human Mucolipin Transient Receptor Potential 1 (TRPML1) [AID624414, Type: screening]MCOLN1 gene product [Homo sapiens] [gi:10092597]
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16
[SID99495574]
 HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity [AID652154, Type: screening]PAX8 [Homo sapiens] [gi:998701]
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17
[SID99495574]
 Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) [AID588352, Type: screening]nuclear receptor coactivator 3 isoform a [Homo sapiens] [gi:32307126]
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18
[SID99495574]
 Luminescence-based cell-based high throughput confirmation assay for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) [AID588792, Type: screening]nuclear receptor coactivator 3 isoform a [Homo sapiens] [gi:32307126]
View
19
[SID99495574]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1) [AID624466, Type: screening]TAAR1 gene product [Homo sapiens] [gi:21264324]
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20
[SID99495574]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1) [AID624466, Type: screening]TAAR1 gene product [Homo sapiens] [gi:21264324]
View
21
[SID99495574]
 Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3): Luminescence-based cell-based high throughput screening assay to identify agonists of the Herpes Virus Virion Protein 16 (VP16) [AID624379, Type: screening]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
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22
[SID99495574]
 Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID651615, Type: screening]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
View
23
[SID99495574]
 Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID588794, Type: screening]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
View
24
[SID99495574]
 Counterscreen for inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1): Luminescence-based cell-based high throughput assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16). [AID588824, Type: screening]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
View
25
[SID99495574]
 Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2): Fluorescence-based cell-based high throughput assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) [AID624371, Type: screening]Beta lactamase [Pseudomonas aeruginosa] [gi:114881106]
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26
[SID99495574]
 S100A4: HTS Measured in Biochemical System Using Plate Reader - 7045-01_Inhibitor_SinglePoint_HTS_Activity [AID652163, Type: screening]S100A4 [Homo sapiens] [gi:47496637]
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27
[SID26543390]
 Fluorescence-based cell-based confirmation assay for antagonists of kappa opioid receptor 1 (OPRK1) [AID652082, Type: other]opioid receptor, kappa 1 [Homo sapiens] [gi:119607129]
View
28
[SID26543390]
 Fluorescence-based cell-based confirmation assay for antagonists of kappa opioid receptor 1 (OPRK1) [AID652082, Type: other]opioid receptor, kappa 1 [Homo sapiens] [gi:119607129]
View
29
[SID26543390]
 Fluorescence-based cell-based confirmation assay for antagonists of kappa opioid receptor 1 (OPRK1) [AID652082, Type: other]opioid receptor, kappa 1 [Homo sapiens] [gi:119607129]
View
30
[SID26543390]
 Fluorescence-based cell-based confirmation assay for antagonists of kappa opioid receptor 1 (OPRK1) [AID652082, Type: other]opioid receptor, kappa 1 [Homo sapiens] [gi:119607129]
View
31
[SID26543390]
 Maybridge screen to identify antagonists of kappa opioid receptor 1 (OPRK1): fluorescence-based cell-based assay [AID652031, Type: screening]opioid receptor, kappa 1 [Homo sapiens] [gi:119607129]
View
32
[SID26543390]
 Maybridge screen to identify antagonists of kappa opioid receptor 1 (OPRK1): fluorescence-based cell-based assay [AID652031, Type: screening]opioid receptor, kappa 1 [Homo sapiens] [gi:119607129]
View
33
[SID26543390]
 Maybridge screen to identify antagonists of kappa opioid receptor 1 (OPRK1): fluorescence-based cell-based assay [AID652031, Type: screening]opioid receptor, kappa 1 [Homo sapiens] [gi:119607129]
View
34
[SID26543390]
 Maybridge screen to identify antagonists of kappa opioid receptor 1 (OPRK1): fluorescence-based cell-based assay [AID652031, Type: screening]opioid receptor, kappa 1 [Homo sapiens] [gi:119607129]
View
35
[SID99495574]
 Counterscreen for antagonists of the galanin Receptor 3 (GalR3): Fluorescence-based cell-based high throughput screening assay to identify non specific agonists of the parental HEK-CNG cells [AID652268, Type: screening]
View
36
[SID26543390]
 Primary Cell Based High Throughput Screening Assay for Inhibitors of TLR4-MyD88 binding [AID811, Type: screening]toll-like receptor 4 [Homo sapiens] [gi:55662034]
View
37
[SID99495574]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID651719, Type: screening]GALR3 gene product [Homo sapiens] [gi:4503907]
View
38
[SID99495574]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID651719, Type: screening]GALR3 gene product [Homo sapiens] [gi:4503907]
View
39
[SID99495574]
 Fluorescence-based cell-based primary high throughput confirmation assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID652245, Type: screening]GALR3 gene product [Homo sapiens] [gi:4503907]
View
40
[SID99495574]
 Fluorescence-based cell-based primary high throughput confirmation assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID652245, Type: screening]GALR3 gene product [Homo sapiens] [gi:4503907]
View
41
[SID99495574]
 Luminescence-based cell-based high throughput confirmation assay for inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1). [AID588820, Type: screening]nuclear receptor coactivator 1 isoform 1 [Homo sapiens] [gi:22538455]
View
42
[SID99495574]
 Luminescence-based cell-based high throughput confirmation assay for inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1). [AID588820, Type: screening]nuclear receptor coactivator 1 isoform 1 [Homo sapiens] [gi:22538455]
View
43
[SID99495574]
 Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1) [AID588354, Type: screening]nuclear receptor coactivator 1 isoform 1 [Homo sapiens] [gi:22538455]
View
44
[SID99495574]
 Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1) [AID588354, Type: screening]nuclear receptor coactivator 1 isoform 1 [Homo sapiens] [gi:22538455]
View
45
[SID99495574]
 Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) [AID624267, Type: screening]RIPK2 gene product [Homo sapiens] [gi:4506537]
View
46
[SID99495574]
 Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) [AID624267, Type: screening]RIPK2 gene product [Homo sapiens] [gi:4506537]
View
47
[SID99495574]
 Fluorescence-based cell-based high throughput confirmation assay for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) [AID624370, Type: screening]RIPK2 gene product [Homo sapiens] [gi:4506537]
View
48
[SID99495574]
 Fluorescence-based cell-based high throughput confirmation assay for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) [AID624370, Type: screening]RIPK2 gene product [Homo sapiens] [gi:4506537]
View
49
[SID99495574]
 Luminescence-based cell-based high throughput confirmation assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624378, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
50
[SID99495574]
 Luminescence-based cell-based high throughput confirmation assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624378, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View