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AC1NWWDF (CID 5714141) - Compound BioActivity Data
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BioActivity Outcomes:
Active(48)
 
 
Inactive(707)
 
 
Inconclusive(32)
 
 
Unspecified(17)
 
 
Top Targets:
7TM GPCR Srx(24)
 
 
7TM GPCR Srsx(21)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
SRC-1(8)
 
 
 
BioAssay Types:
Screening(518)
 
 
 
 
Confirmatory(222)
 
 
 
 
 
Literature(41)
 
 
 
 
 
BioActivity Types:
Potency(155)
 
 
 
 
 
IC50(54)
 
 
 
 
 
EC50(9)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 727    Data Row: 804   Total Pages: 41   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17510019]
AbsAC35_uM 0.155Counterscreen for inhibitors of NLG for Luciferase Activators Measured in Cell-Based System Using Plate Reader - 2146-03_Inhibitor_Dose_CherryPick_Activity [AID624404, Type: confirmatory]
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2
[SID17510019]
Potency 1.1995qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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3
[SID17510019]
Potency 2.2387qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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4
[SID17510019]
AbsAC26_uM 3.79Luciferase Reporter Cell Based HTS to identify inhibitors of N-linked Glycosylation Measured in Cell-Based System Using Plate Reader - 2146-01_Inhibitor_Dose_CherryPick_Activity [AID624491, Type: confirmatory]
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5
[SID17510019]
IC50 5.24Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) (2K validation set) [AID504319, Type: confirmatory]perilipin-5 [Homo sapiens] [gi:116292172]
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6
[SID17510019]
IC50 5.24Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) (2K validation set) [AID504319, Type: confirmatory]1-acylglycerol-3-phosphate O-acyltransferase ABHD5 [Homo sapiens] [gi:31542303]
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7
[SID17510019]
IC50 5.39Counterscreen for inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID602236, Type: confirmatory]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
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8
[SID17510019]
IC50 5.597Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1) (2K validation set) [AID504317, Type: confirmatory]perilipin-1 [Homo sapiens] [gi:223718203]
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9
[SID17510019]
IC50 5.597Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1) (2K validation set) [AID504317, Type: confirmatory]1-acylglycerol-3-phosphate O-acyltransferase ABHD5 [Homo sapiens] [gi:31542303]
View
10
[SID17510019]
IC50 5.957Counterscreen for inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) [AID602234, Type: confirmatory]nuclear receptor coactivator 3 isoform a [Homo sapiens] [gi:32307126]
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11
[SID17510019]
IC50 6.335Luminescence-based cell-based high throughput dose response assay for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) [AID602166, Type: confirmatory]nuclear receptor coactivator 3 isoform a [Homo sapiens] [gi:32307126]
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12
[SID103655170]
IC50 9.3Cytotoxicity against human PC3 cells after 72 hrs by MTT assay [AID664955, Type: Literature]
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13
[SID103655170]
IC50 13.49Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay [AID664957, Type: Literature]
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14
[SID103655170]
IC50 13.69Cytotoxicity against human PANC1 cells after 72 hrs by MTT assay [AID664956, Type: Literature]
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15
[SID17510019]
Potency 14.1254Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504848, Type: confirmatory]
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16
[SID17510019]
Potency 15.8489Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504850, Type: confirmatory]
View
17
[SID17510019]
Potency 15.8489VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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18
[SID17510019]
Potency 16.3601qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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19
[SID103655170]
EC50 17.1Inhibition of Wnt3A/beta-catenin signaling in HEK293 cells after 24 hrs by firefly/renilla dual luciferase reporter gene assay [AID1062641, Type: Literature]
View
20
[SID17510019]
Potency 19.0115qHTS for antagonists of the Thyroid Stimulation Hormone Receptor: Hit Validation in Primary Screen [AID602292, Type: confirmatory]TSHR protein [Homo sapiens] [gi:118341367]
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