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BioActivity Data for Compound 10B-060 (CID 5706877)

BioActivity Outcomes:
Active(8)
 
 
Inactive(655)
 
 
Inconclusive(15)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(41)
 
 
Bcl-2 like(11)
 
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
Tryp SPc(7)
 
 
BioAssay Types:
Screening(456)
 
 
 
 
Confirmatory(198)
 
 
 
 
 
Literature(11)
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(109)
 
 
Toxicity(5)
 
 
 
Cell-based(131)
 
 
 
 
Organism-base..(11)
 
 
BioActivity Types:
Potency(145)
 
 
 
 
 
IC50(39)
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 615    Data Row: 679   Total Pages: 34   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24824551]
Potency 2.5119qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
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2
[SID24824551]
Potency 3.9811qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
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3
[SID24824551]
Primary screen for compounds that activate Alzheimer's amyloid precursor [AID1276, Type: screening]amyloid precursor protein, partial [Homo sapiens] [gi:257380]
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4
[SID24824551]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
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5
[SID24824551]
Primary cell-based high throughput screening assay to measure STAT1 activation [AID932, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
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6
[SID24824551]
uHTS of Mcl-1/Noxa interaction inhibitors [AID1022, Type: screening]Mcl-1 [Homo sapiens] [gi:7582271]
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7
[SID24824551]
Luminescent GLuc Reporter Gene Assay Primary HTS to Identify Small Molecule Activator of Glucose Dependent Insulin Secretion Measured in Cell-Based System Using Plate Reader - 7055-01_Activator_SinglePoint_HTS_Activity [AID743287, Type: screening]
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8
[SID24824551]
Heat Shock Factor-1 (HSF-1) Measured in Cell-Based System Using Plate Reader - 2038-01_Activator_SinglePoint_HTS_Activity [AID504408, Type: screening]
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9
[SID24824551]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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10
[SID24824551]
Potency 1.0399qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 [AID2288, Type: confirmatory]
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11
[SID24824551]
Potency 1.7783qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624287, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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12
[SID24824551]
Potency 2.9362Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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13
[SID24824551]
Potency 12.5893High Throughput Screening for Foot and Mouth Disease Virus Antivirals [AID1159524, Type: confirmatory]
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14
[SID24824551]
NIH Compound Library Profiling: Compound and DTT Dependent Redox Cycling H2O2 Generation. [AID878, Type: screening]
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15
[SID24824551]
Screen for Chemicals that Inhibit the RAM Network [AID868, Type: screening]
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16
[SID24824551]
Counter Screen for Luciferase-based Primary Inhibition Assays [AID1006, Type: screening]
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17
[SID24824551]
Counter Screen for Luciferase-based Primary Stimulation Assays [AID1027, Type: screening]
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18
[SID24824551]
Leishmania major promastigote HTS [AID1063, Type: screening]
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19
[SID24824551]
EC50 High Throughput Screen for Inhibitors of ER Stress-induced Cell Death in a 384 well format. [AID1222, Type: confirmatory]
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20
[SID24824551]
Anti-Viral Drugs Against Arbovirus Infections, a Primary Screen [AID1251, Type: screening]
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