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Sisomicin (CID 5702115) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(15)
 
 
Inconclusive(23)
 
 
Unspecified(10)
 
 
Top Targets:
crotonase-lik..(1)
 
 
Chorismate bi..(1)
 
 
23DHB-AMP lg(1)
 
 
HTH MARR(1)
 
 
DNA pol B 3(1)
 
 
BioAssay Types:
Screening(3)
 
 
Literature(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 46    Data Row: 48   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID8149526]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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2
[SID8149526]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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3
[SID8149526]
Screen for compounds that correct neuronal dysfunction without cell death as induced by the expression of polyglutamine-expanded, N-terminal huntingtin in C. elegans mechanosensory neurons (HDELENEU) [AID1599, Type: other]
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4
[SID8149526]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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5
[SID8149526]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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6
[SID8149526]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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7
[SID8149526]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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8
[SID8149526]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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9
[SID8149526]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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10
[SID8149526]
Screening of compounds showing protective effect against cell death induced by familial amyotrophic lateral sclerosis (FALS)-linked mutantsuperoxide dismutase 1 (SOD1) (ALSOD1) [AID1605, Type: other]
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11
[SID92124244]
A screen for compounds that inhibit liver stage malaria [AID624349, Type: other]
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12
[SID92307651]
A screen for compounds that inhibit liver stage malaria [AID624349, Type: other]
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13
[SID99301615]
A screen for compounds that inhibit processive DNA synthesis of vaccinia virus [AID493162, Type: other]DNA polymerase [Vaccinia virus] [gi:335756]
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14
[SID92124244]
Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection [AID720717, Type: other]ORF 73 [Human herpesvirus 8 type M] [gi:1718329]
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15
[SID92307651]
Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection [AID720717, Type: other]ORF 73 [Human herpesvirus 8 type M] [gi:1718329]
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16
[SID92124244]
A screen for compounds that inhibit replication of Vibrio cholerae chromosome II [AID504770, Type: other]hypothetical protein VC_A0002 [Vibrio cholerae O1 biovar El Tor str. N16961] [gi:9657380]
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17
[SID92124244]
A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis [AID540299, Type: Literature]Naphthoate synthase MenB (dihydroxynaphthoic acid synthetase) (DHNA synthetase) [Mycobacterium tuberculosis H37Rv] [gi:15607688]
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18
[SID92307651]
A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus [AID720641, Type: other]anion-binding protein [Staphylococcus aureus subsp. aureus Mu50] [gi:15923709]
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19
[SID26611918]
Modulators of the EP2 prostaglandin E2 receptor - Primary Screening [AID940, Type: screening]prostaglandin E2 receptor EP2 subtype [Homo sapiens] [gi:31881630]
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20
[SID26611918]
Inhibitors of the EP2 Prostaglandin E2 Receptor - Primary Screen [AID1422, Type: screening]prostaglandin E2 receptor EP2 subtype [Homo sapiens] [gi:31881630]
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21
[SID99301615]
A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis [AID492967, Type: other]gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:47566732]
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22
[SID92124244]
A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities [AID588519, Type: Literature]Chain A, Poliovirus Polymerase With Gtp [gi:52695378]
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23
[SID92124244]
A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme MbtI [AID493033, Type: other]Isochorismate synthase/isochorismate lyase [gi:81706979]
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24
[SID92124244]
A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme BasE [AID485350, Type: screening]enterobactin synthase subunit E [Acinetobacter baumannii ATCC 17978] [gi:126642418]
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25
[SID92124244]
A screen for compounds that modulate the activity of the Staphylococcus aureus MgrA protein [AID602314, Type: other]MarR family regulatory protein [Staphylococcus aureus subsp. aureus str. Newman] [gi:151220867]
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26
[SID8149526]
Yeast Assay for Parkinson's Disease (YAPD) [AID1600, Type: other]
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27
[SID8149526]
Screen for compounds that suppress mutant SOD1-mediated cell death (mSODtox) [AID1601, Type: other]
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28
[SID8149526]
Screen for compounds that attenuate mutant SOD1 toxicity (mSOD1) [AID1602, Type: other]
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29
[SID8149526]
Screen for compounds that decrease glutamate induced motor neuron death measured by TUNEL staining for DNA degradation (MNGlu) [AID1594, Type: other]
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30
[SID8149526]
Suppression of Polyglutamine Toxicity in Whole Organism Drosophila Model of SCA1 (SCA1FLYe) [AID1595, Type: other]
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31
[SID8149526]
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells (LDH100) [AID1596, Type: other]
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32
[SID8149526]
Suppression of Polyglutamine Toxicity in Whole Organism Drosophila Model of SCA1 (SCA1FLYp) [AID1597, Type: other]
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33
[SID8149526]
Screen for compounds that selectively increase SMN2 splicing relative to SMN1 splicing (SMNLUC) [AID1598, Type: other]
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34
[SID8149526]
Screen for compounds that inhibit in vitro mutant huntingtin aggregation (QA1) [AID1584, Type: other]
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35
[SID8149526]
Screen for compounds that inhibit the ability of solid phase synthetic polyglutamine aggregates to elongate by incorporating solution-phase biotin-tagged, monomeric polyglutamine (QA3) [AID1585, Type: other]
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36
[SID8149526]
A 2-Hybrid Test for Interactions Between Polyglutamine-Containing Proteins in the Yeast Nucleus (Qn2Hy) [AID1586, Type: other]
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37
[SID8149526]
Screen for compounds that increase the expression of EAAT-2 in rat spinal cord organotypic slice cultures (X4_EAAT2) [AID1587, Type: other]
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38
[SID8149526]
Screen for compounds that reduce polyglutamine aggregation as measured by turbidity (QTHIO) [AID1588, Type: other]
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39
[SID8149526]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (SDS) [AID1589, Type: other]
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40
[SID8149526]
Cellular toxicity caused by inducible expressing of N-terminal huntingtin with expanded ployglutamine repeat (Htt-N63-148Q) in PC12 cells (ROSShtt) [AID1590, Type: other]
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41
[SID8149526]
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells (LDH20) [AID1606, Type: other]
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42
[SID8149526]
Screen for compounds that promote the turnover of an expanded polyglutamine androgen receptor (AR112GFP) [AID1607, Type: other]
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43
[SID8149526]
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells (LDH016) [AID1608, Type: other]
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44
[SID8149526]
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells (LDH08) [AID1609, Type: other]
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45
[SID8149526]
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells [AID1610, Type: other]
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46
[SID8149526]
Screen for compounds that inhibit mitochondrial permeability transition (MitoPT) [AID1580, Type: other]
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47
[SID8149526]
Screen of Compounds to Block PAR4 - aPKC Interaction for Treatment of Neurodegeneration (Par4_PKC) [AID1581, Type: other]
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48
[SID8149526]
Yeast cell-based screen for Novel HDAC inhibitors using a PHO84-LacZ reporter gene (PHO84) [AID1582, Type: other]
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