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AGN-PC-0BKY48 (CID 56951834) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(11)
 
 
Top Targets:
DUF3371(5)
 
 
BioAssay Types:
Confirmatory(11)
 
 
BioActivity Types:
AC50(11)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 11    Data Row: 11   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID135659560]
AC50_uM 0.0779MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624290, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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2
[SID135659560]
AC50_uM 0.0923MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set5 [AID624363, Type: confirmatory]
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3
[SID135659560]
AC50_uM 0.107MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624316, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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4
[SID135659560]
AC50_uM 0.274MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624289, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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5
[SID135659560]
AC50_uM 0.7MITF Orthogonal Assay: MALME3 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-04_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624299, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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6
[SID135659560]
AC50_uM 0.79MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set3 [AID624315, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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7
[SID135659560]
AC50_uM 0.843MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624366, Type: confirmatory]
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8
[SID135659560]
AC50_uM 2.59MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624489, Type: confirmatory]
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9
[SID135659560]
AC50_uM 8.92MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624364, Type: confirmatory]
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10
[SID135659560]
AC50_uM 9.29MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_DryPowder_Activity_Set3 [AID624324, Type: confirmatory]
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11
[SID135659560]
AC50_uM 23.04MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_DryPowder_Activity_Set5 [AID624368, Type: confirmatory]
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