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BRD-A60337045-001-01-5 (CID 56851828) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(7)
 
 
Top Targets:
Ntn CA(12)
 
 
 
BioAssay Types:
Confirmatory(12)
 
 
 
BioActivity Types:
AC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 12    Data Row: 12   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID135383886]
AC50_uM 1.63Fluorescent Biochemical Primary HTS to Identify Inhibitors of P. aeruginosa PvdQ acylase Measured in Biochemical System Using Plate Reader - 2091-02_Inhibitor_Dose_DryPowder_Activity_Set4 [AID623993, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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2
[SID135383886]
AC50_uM 3.47Fluorescent Biochemical Primary HTS to Identify Inhibitors of P. aeruginosa PvdQ acylase Measured in Biochemical System Using Plate Reader - 2091-02_Inhibitor_Dose_DryPowder_Activity_Set3 [AID623991, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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3
[SID135383886]
AbsAC35_uM 42.26Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK pump mutant mexAB-OprM strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-10_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624104, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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4
[SID135383886]
AbsAC35_uM 116.72Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK pump mutant mexAB-OprM strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-10_Inhibitor_Dose_DryPowder_Activity [AID624105, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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5
[SID135383886]
AbsAC35_uM 387.3Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK strain (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-08_Inhibitor_Dose_DryPowder_Activity [AID624107, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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6
[SID135383886]
AbsAC40_uM Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 405 nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity_Set6 [AID624109, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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7
[SID135383886]
AbsAC35_uM Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK strain (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-08_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624106, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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8
[SID135383886]
AC50_uM Counterscreen measuring mammalian cell toxicity screen in HeLa cells of pyoverdine inhibitors Measured in Cell-Based System Using Plate Reader - 2091-03_Inhibitor_Dose_DryPowder_Activity_Set3 [AID623987, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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9
[SID135383886]
AC50_uM Counterscreen measuring mammalian cell toxicity screen in HeLa cells of pyoverdine inhibitors Measured in Cell-Based System Using Plate Reader - 2091-03_Inhibitor_Dose_DryPowder_Activity_Set2 [AID623990, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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10
[SID135383886]
AbsAC35_uM Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 600 nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity_Set7 [AID624064, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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11
[SID135383886]
AbsAC35_uM Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 405 nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity_Set5 [AID624070, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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12
[SID135383886]
AbsAC35_uM Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 405 nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity_Set8 [AID624102, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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